SLU-PP-332 is a synthetic estrogen-related receptor (ERR) agonist developed as a research tool for investigating exercise-responsive metabolic pathways. It has attracted attention for its ability to activate molecular programs associated with aerobic exercise in preclinical models.

Product Information

SLU-PP-332 acts primarily through ERR alpha, ERR beta, and ERR gamma, with particularly strong activity at ERR alpha. Animal research has linked the compound to increased mitochondrial function, oxidative muscle fibers, fatty-acid oxidation, and exercise endurance.

How It Works

SLU-PP-332 activates ERR nuclear receptors that regulate genes involved in mitochondrial metabolism, oxidative phosphorylation, and fatty-acid utilization. This can trigger a molecular response resembling aspects of aerobic exercise.

POTENTIAL BENEFITS

1. Exercise-Mimetic Activity

SLU-PP-332 can activate an acute aerobic-exercise gene program in experimental models. This makes it one of the most prominent small molecules currently studied as a pharmacological exercise mimetic.

2. Supports Mitochondrial Function

Cellular and animal research indicates that SLU-PP-332 increases mitochondrial function and cellular respiration, providing a mechanistic basis for its metabolic effects.

3. Enhanced Exercise Endurance

In mice, SLU-PP-332 increased oxidative skeletal-muscle fibers and improved exercise endurance. These findings have driven interest in ERR activation as a strategy for improving muscle metabolic capacity.

4. Metabolic Health Research

Animal models of obesity and metabolic syndrome have shown increased energy expenditure, greater fatty-acid oxidation, reduced fat accumulation, and improved insulin sensitivity following SLU-PP-332 exposure.

Dosage

There is no established human dosage for SLU-PP-332. The compound remains primarily a preclinical research tool, and animal doses should not be interpreted as human dosing recommendations. Recent literature continues to describe it as an emerging exercise mimetic requiring further research.

Side Effects

Human safety data are not established. Potential long-term effects of sustained ERR activation, cardiovascular effects, metabolic disturbances, and interactions with other metabolic agents remain important unanswered questions.

References

1. PubMed - SLU-PP-332 exercise-mimetic research PubMed
2. PubMed - SLU-PP-332 metabolic syndrome research PubMed
3. PubMed - SLU-PP-332 doping-control research PubMed

Note: BehemothLabz does not sell this product. Purchase links on this page may direct you to third-party suppliers through affiliate links.

CAS number:

• Silymarin: 65666-07-1
• Tudca: 14605-22-2

Molar mass: 

• Silymarin: 482.44 g/mol
• Tudca: 499.7036 g/mol

Chemical formula: 

• Silymarin: C25H22O10
• Tudca: C26H45NO6S

IUPAC name:

• Silymarin: (2R,3R)-3,5,7-trihydroxy-2-[(2R,3R)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl) -2,3-dihydrobenzo[b][1,4]dioxin-6-yl]chroman-4-one
• Tudca: 2-[[(4R)-4-[(3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]ethanesulfonic acid

Synonyms:

• Silymarin: Milk Thistle 
• Tudca: Tauroursodeoxycholic acid

Packaged in an air-sealed mylar bag. Keep contents sealed and stored in a cool, dry place.  Items are shipped in plain envelopes or bubble mailers within 24-48 hours (or the next business day).

It is important to note that, like all other research compounds, Sylimarin 98% TUDCA capsules are only intended for research purposes and are not intended for human consumption. Behemoth Labz sells this product solely for research purposes, and any other use is not endorsed or recommended. Please follow all safety precautions and handling instructions when using this product for research purposes.

What is Silymarin 98%?

Silymarin 98% is a natural dietary research compound derived from the milk thistle plant. (R)(R)

What is TUDCA

TUDCA is known as Tauroursodeoxycholic acid, a naturally occurring bile salt in the body.

Note: To expand your research on liver support, we recommend exploring our SARM Support products, which can complement the benefits of Silymarin 98% + TUDCA. For those researching anti-estrogenic compounds, our Raloxifene offers promising potential. Additionally, check out Annihilate Capsules and Yohimbine Capsules to support your studies further.

BEHEMOTH LABZ DISCLAIMER

Please make sure you go through the Terms and Conditions, and please familiarize yourself with it as it is important. Please research the scientific uses of this product before making any purchases. Make note that the packaging and labels of the product may differ from those shown on the website.
You are welcome to review our Terms and Conditions. If you have questions about a listed product, reach us at support@behemothlabz.com.

Osthole, also known as 7-methoxy-8-(3-methyl-2-butenyl) coumarin, is a naturally occurring compound classified as a coumarin derivative. It can be found in certain plants and fruit, with Cnidium monnieri (commonly known as Cnidium or She Chuang Zi) and Angelica archangelica (commonly known as Angelica or Dong Quai) being the primary sources. The compound has been studied in traditional Chinese medicine for centuries due to its reputed health benefits.

Osthole 98% represents a fascinating natural compound with multifaceted potential across various therapeutic areas. As research advances, its applications in inflammation management, neuroprotection, cardiovascular health, cancer treatment, and bone health are becoming more evident. 

The production of Osthole involves multiple steps, and chemical intermediates play a crucial role in these processes. The different intermediates are typically transient compounds that undergo further reactions and transformations to ultimately yield the final product, which is Osthole in its pure and concentrated form. 

How Does Osthole Work?

Osthole 98% exhibits a diverse range of biological effects. Its mechanism of action involves intricate interactions with various molecular pathways and cellular processes. Although not all mechanisms have been fully elucidated, research has provided insights into some key ways in which Osthole 98% exerts its effects.

Osthole has the potential to interact with specific receptors on the cell surface, initiating intracellular signaling pathways. 

Additionally, Osthole can modulate enzyme activity, impacting essential cellular processes. This versatile compound also regulates gene expression, influencing protein synthesis and other molecular functions. 

Osthole’s anti-inflammatory properties are attributed to its inhibition of pro-inflammatory molecules, while its antioxidant activity neutralizes harmful free radicals, guarding against oxidative stress. 

Furthermore, it exhibits neuroprotective properties, shielding nerve cells from damage and supporting their survival. Osthole’s ability to stimulate osteoblasts and inhibit osteoclasts fosters healthy bone metabolism.

Although scientific research has provided insights into these mechanisms, further investigation is required to fully comprehend Osthole’s potential therapeutic applications. 

Chemical Properties of Osthole 98% Capsules

• CAS Number: 484-12-8
• Molar Mass: 244.28 g/mol
• Chemical Formula: C15H16O3
• IUPAC Name: 7-Methoxy-8-(3-methylbut-2-en-1-yl)chromen-2-one
• Synonyms: Osthol, Ostholin, Ostholine, Ostrodin, Ostrosin, Ostroside, Cnidilin, Khellol Glucoside 

The designation “Osthole 98%” refers to a highly concentrated form of the compound, where the extract has been refined to contain 98% pure Osthole. This purification process ensures the potency and efficacy of the compound, making it suitable and potential for various therapeutic applications.

Research Applications of Osthole 98%

Anti-Inflammatory Activity in Experimental Models

In preclinical studies, Osthole has demonstrated measurable anti-inflammatory effects. Experimental findings indicate that it may reduce the expression of pro-inflammatory mediators and signaling molecules in cell-based and animal models, making it relevant for studying inflammatory pathways.

Antioxidant Activity in Cellular Systems

Osthole has been investigated for its antioxidant properties in laboratory settings. Studies suggest it can help neutralize reactive oxygen species (ROS) and reduce oxidative stress markers in cells, supporting its use in oxidative stress–related research models.

Neuroprotective Effects in Preclinical Studies

Initial research shows that Osthole may influence neuronal cell function in experimental systems. It has been studied for its potential to support neuronal cell integrity and modulate pathways associated with neurodegeneration in in vitro and in vivo models.

Cardiovascular-Related Effects in Research Models

In experimental studies, Osthole has shown vasorelaxant effects and interactions with pathways involved in vascular function. It has also been examined for its influence on lipid metabolism and blood flow dynamics in laboratory models.

Antiproliferative Effects in Cell-Based Studies

Osthole has been explored in cancer-related research for its effects on cell proliferation. Findings from in vitro studies suggest it may induce apoptosis and influence cell cycle regulation in certain cancer cell lines, supporting further investigation in oncology research.

Effects on Bone Metabolism in Experimental Systems

Research suggests that Osthole may modulate bone-related cellular activity. Studies indicate it can influence osteoblast differentiation and inhibit osteoclast activity in laboratory models, making it of interest in bone metabolism research.

Note: Osthole (especially in purified forms such as 98%) is not an FDA-approved dietary ingredient and is generally not classified as a standard dietary supplement. While plant extracts containing osthole (e.g., from Cnidium monnieri) may be marketed as supplements, they are not approved for the treatment of any medical conditions.

DISCLAIMER

Please make sure you go through the Terms and Conditions, and please familiarize yourself with them as they are important. Please research the scientific uses of this product before making any purchases. Make note that the packaging and labels of the product may differ from those shown on the website.

You are welcome to review our Terms and Conditions. If you have questions about a listed product, reach us at support@behemothlabz.com.

ATTENTION: All BehemothLabz products are strictly for LABORATORY AND RESEARCH PURPOSES ONLY. They are not to be used for any human or veterinary purposes.

Reference Links

Jasemi, S. V., Khazaei, H., Morovati, M. R., Joshi, T., Aneva, I. Y., Farzaei, M. H., & Echeverría, J. (2024). Phytochemicals as treatment for allergic asthma: Therapeutic effects and mechanisms of action. Phytomedicine, 122, 155149. https://doi.org/10.1016/j.phymed.2023.155149

Michał Zimecki, Jolanta Artym, Cisowski, W., Mażol, I., Maciej Włodarczyk, & Michał Glenśk. (2009). Immunomodulatory and Anti-Inflammatory Activity of Selected Osthole Derivatives. Zeitschrift Für Naturforschung C, 64(5-6), 361–368. https://doi.org/10.1515/znc-2009-5-610

Sun, M., Sun, M., & Zhang, J. (2021). Osthole: an overview of its sources, biological activities, and modification development. Medicinal Chemistry Research, 30(10), 1767–1794. https://doi.org/10.1007/s00044-021-02775-w

García-Arroyo, F. E., Gonzaga-Sánchez, G., Silva-Palacios, A., Roldán, F. J., Loredo-Mendoza, M. L., Yamnia Quetzal Alvarez-Alvarez, Jesus, Vélez, K. A., Tapia, E., Osorio-Alonso, H., Arellano-Buendía, A. S., Sánchez-Gloria, J. L., Lanaspa, M. A., Johnson, R. J., & Sánchez-Lozada, L. G. (2023). Osthole Prevents Heart Damage Induced by Diet-Induced Metabolic Syndrome: Role of Fructokinase (KHK). Antioxidants, 12(5), 1023–1023. https://doi.org/10.3390/antiox12051023

Zhang, Z., Wing Nang Leung, Li, G., Siu Cheung Kong, Tang, Y., Yin Ping Wong, & Chun Man Chan. (2017). Osthole Enhances Osteogenesis in Osteoblasts by Elevating Transcription Factor Osterix via cAMP/CREB Signaling In Vitro and In Vivo. 9(6), 588–588. https://doi.org/10.3390/nu9060588

Bemethyl, also known as Bemetil or Metaprot, is a synthetic compound developed and studied primarily in Eastern European research. It has been investigated for effects on physical performance, fatigue resistance, adaptation to stress, and cognitive or psychostimulant activity.

Product Information

Bemethyl belongs to the benzimidazole class and has been studied as a synthetic adaptogenic and psychostimulant compound. Clinical literature has examined its effects under conditions of physical and environmental stress. Bemethyl is also known as Bemetil, Bemitil, Bemitil/Metaprot, and is sometimes referred to as Metaprot in the literature.

How It Works

Bemethyl appears to influence cellular adaptation to stress and may affect energy metabolism and central nervous system activity. Its precise mechanism is broader and less clearly defined than that of conventional stimulants.

POTENTIAL BENEFITS

1. Physical-Endurance Research

Human studies have investigated Bemethyl during strenuous physical exertion, including research into work capacity and resistance to environmental stress.

2. Fatigue Research

Clinical research has evaluated Bemethyl in asthenic and fatigue-related conditions, with reported effects on subjective and functional measures.

3. Stress-Adaptation Research

Bemethyl has been investigated for its ability to influence physiological adaptation under challenging environmental conditions, including heat and physical workload.

4. Cognitive & Psychostimulant Research

Published clinical literature describes mild psychostimulant effects and changes in neuropsychological symptoms, making Bemethyl relevant to research into fatigue and alertness.

Dosage

Published human research has used different protocols. One controlled study examined a single 0.5 g dose during intensive physical exertion, while older clinical research used repeated treatment schedules. These historical study protocols should not be treated as a universal modern dosing recommendation.

Side Effects

Reported effects vary with dose and treatment schedule. Because Bemethyl has psychostimulant activity, potential concerns include overstimulation, sleep disturbance, cardiovascular effects, and other CNS-related reactions.

References

1. PubMed — Bemethyl in asthenic disorders. PMID: 3381606
2. Makarov et al. — Bemethyl and thermal resistance during physical exertion. PMID: 9162292
3. PubMed — Bemethyl pharmacology

Note: BehemothLabz does not sell this product. Purchase links on this page may direct you to third-party suppliers through affiliate links.

Annihilate Capsules (Arimistane + N-Acetyl Cysteine + 5a Hydroxy Laxogenin) is a unique product by BehemothLabz that contains different research compounds being studied for their capability of building skeletal contractile tissue in different research subjects. BehemothLabz sells Annihilate Capsules (Arimistane + N-Acetyl Cysteine + 5a Hydroxy Laxogenin) solely for research purposes.

Annihilate Capsules (Arimistane + N-Acetyl Cysteine + 5a Hydroxy Laxogenin) Product Details

Arimistane

• CAS number is stated as 1420-49-1.
• Molar Mass is 284.4 g.mol-1.
• It has a chemical Formula as C19H2202.
• IUPAC Name is (8R,9S,10R,13S,14S)-10,13-dimethyl-2,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthrene-7,17-diSynonyms know antonyms as Androsta-3,5-diene-7,17-dione, NSC 134910

Five alpha Hydroxy Laxogenin

• CAS Number is stated as 56786-63-1
• Molar Mass is 446.6 g/mol
• It has a Chemical Formula of C27H42O5
• IUPAC Name is (1S,2S,4S,5’R,6R,7S,8R,9S,12S,13R,16S,18R)-16,18-dihydroxy-5′,7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icosane-6,2′-oxane]-19-one
• Also known by Synonyms as 56786-63-1; 5alpha-Hydroxy laxogenin; Spirostan-6-one, 3,5-dihydroxy-, (3b,5a,25R)

NAC

• CAS Number is stated as 616-91-1
• Molar Mass is 163.19 g/mol
• It has a Chemical Formula of C5H9NO3S
• IUPAC Name is 2-acetamido-3-sulfanylpropanoic acid
• Also known by Synonyms as N-Acetyl-Cysteine

What is Annihilate Capsules (Arimistane + N-Acetyl Cysteine + 5a Hydroxy Laxogenin)? 

Annihilate Capsules (Arimistane + N-Acetyl Cysteine + 5a Hydroxy Laxogenin) is a holistic experimental compound of BehemothLabz. It consists of 3 potentially beneficial ingredients: Arimistane, 5 Alpha Hydroxy Laxogenin, and N-Acetyl Cysteine (NAC). 

Annihilate Capsules may also (Arimistane + N-Acetyl Cysteine + 5a Hydroxy Laxogenin) demonstrate potential anabolic effects in controlled experimental models. 

Ingredients: Per Capsule
Arimistane – 60mg
N-Acetyl-Cysteine (NAC) – 150mg
5a Hydroxy Laxogenin –  50mg

Annihilate Capsules (Arimistane + N-Acetyl Cysteine + 5a Hydroxy Laxogenin) contains 60 mg Arimistane, 150 mg NAC, 50mg 5a Hydroxy Laxogenin, totaling 260 mg per capsule.

What is Arimistane? 

Arimistane (Androsta-3,5-diene-7,17-dione) (3-deoxy-7-oxo-DHEA) is a 7-Keto DHEA metabolite that does not convert to testosterone or estrogen. In different research settings, Arimistane has been shown to inhibit aromatase. It binds with the aromatase and serve as an estrogen blocker.

What is 5 Alpha Hydroxy Laxogenin?

Laxogenin compounds belong to a group of 40 plant-based steroids known as brassinosteroids. They are only found in trace amounts in various plants and foods.

Laxogenin promotes plant growth and vitality and has a similar anabolic/androgenic ratio to Anavar, a popular oral anabolic steroid (also known as Oxandrolone).

N-Acetyl-Cysteine (NAC)

Cysteine is a semi-essential amino acid available synthetically as N-acetyl cysteine (NAC). After consumption, NAC breaks down into cysteine, which is then transformed into glutathione.

Glutathione is a critical intracellular antioxidant. In various research and experimental settings, Glutathione has been seen to play a key role in immune function, detoxification processes, and cellular repair mechanism.

Note: For comprehensive research support, explore our SARM Support section, where you’ll find compounds designed to aid research efforts. If you’re interested in additional estrogen blockers, check out 5a-Hydroxy Laxogenin Capsules, which is often studied for its potential aromatase-inhibiting properties. Additionally, you can find more details about Silymarin 98% + TUDCA Capsules for research applications.

Why Buy Annihilate Capsules (Arimistane + N-Acetyl Cysteine + 5a Hydroxy Laxogenin) from BehemothLabz?

BehemothLabz is the best place to purchase Arimistane + N-Acetyl Cysteine + 5a Hydroxy Laxogenin.

We have been around since 2014, supplying the highest-quality research compounds money can buy. Our products come with a 100% satisfaction guarantee, free and fast shipping, and a money-back guarantee on Arimistane + N-Acetyl Cysteine + 5a Hydroxy Laxogenin.

BEHEMOTHLABZ DISCLAIMER

Please make sure you go through the Terms and Conditions, and please familiarize yourself with them as they are important. Please research the scientific uses of this product before making any purchases. Make note that the packaging and labels of the product may differ from those shown on the website.
You are welcome to review our Terms and Conditions. If you have questions about a listed product, reach us at support@behemothlabz.com.

All BehemothLabz products are strictly for LABORATORY AND RESEARCH PURPOSES ONLY. They are not to be used for any human or veterinary purposes.

5α-Hydroxy Laxogenin is a plant-derived steroidal sapogenin classified within the broader group of brassinosteroids. It is structurally related to naturally occurring compounds identified in certain plant species, including those within the Smilax genus.

In controlled research environments, this compound is examined for its structural characteristics and its interaction with intracellular signaling components. Its classification as a brassinosteroid-like molecule allows for investigation into pathways associated with plant-derived steroid analogs and their molecular behavior.

This compound is supplied strictly for laboratory research purposes and is not intended for consumption, medical, or diagnostic use.

Mechanism of Action

At the molecular level, 5α-Hydroxy Laxogenin is studied for its interaction with intracellular signaling pathways associated with protein turnover and cellular regulatory mechanisms. Research focuses on how this compound may influence signaling cascades involved in transcriptional activity and protein synthesis regulation.

Additionally, investigations explore its interaction with pathways related to proteolytic processes and regulatory signaling molecules. These studies are conducted in vitro to evaluate how structural features of brassinosteroid-like compounds contribute to pathway modulation and intracellular signaling dynamics.

The compound is also examined for its potential role in influencing receptor-independent signaling mechanisms, allowing researchers to better understand how plant-derived steroid analogs interact with cellular systems at the biochemical level.

Chemical Properties of 5α-Hydroxy Laxogenin

Research Applications

Intracellular Signaling Pathway Studies

5α-Hydroxy Laxogenin is utilized in experimental systems to examine signaling cascades associated with transcriptional regulation and intracellular communication. Researchers analyze how structural variations influence pathway activity at the molecular level.

Protein Turnover and Regulatory Mechanism Analysis

This compound is applied in studies investigating protein synthesis and degradation pathways. Its interaction with intracellular systems supports evaluation of how regulatory mechanisms maintain protein balance within controlled environments.

Brassinosteroid Analog Research

As a member of the brassinosteroid class, 5α-Hydroxy Laxogenin is used to explore structure-activity relationships among plant-derived steroidal compounds. These studies focus on molecular configuration, binding interactions, and pathway modulation.

Why Choose BehemothLabz to Buy 5α-Hydroxy Laxogenin for Research

BehemothLabz provides research-grade 5α-Hydroxy Laxogenin manufactured under controlled laboratory conditions with strict quality assurance protocols. Each batch undergoes analytical verification to ensure consistency in molecular composition and purity.

Comprehensive documentation, including laboratory testing reports and sourcing transparency, supports reproducibility in experimental settings. BehemothLabz maintains a compliance-focused approach, supplying compounds intended strictly for laboratory-based investigation and analytical research

Disclaimer

5α-Hydroxy Laxogenin is intended strictly for laboratory research and analytical purposes only. It is not intended for use in diagnostic procedures, therapeutic applications, or in vivo studies of any kind.

Any references to biochemical pathways, receptor interactions, or enzymatic processes are provided solely for informational and research-context purposes. This compound must be handled exclusively by qualified professionals in controlled laboratory environments in accordance with applicable regulations and safety guidelines.

Improper handling or use outside of controlled research settings is strictly prohibited.

References

• Beer, C., & Keiler, A. M. (2022). Androgenic properties of the dietary supplement 5α-hydroxy-laxogenin. Archives of toxicology, 96(7), 2139–2142. https://doi.org/10.1007/s00204-022-03283-5
• Avula, B., Chittiboyina, A. G., Bae, J. Y., Haider, S., Wang, Y. H., Wang, M., Zhao, J., Deuster, P. A., & Khan, I. A. (2019). The power of hyphenated chromatography-Time of flight mass spectrometry for unequivocal identification of spirostanes in bodybuilding dietary supplements. Journal of pharmaceutical and biomedical analysis, 167, 74–82. https://doi.org/10.1016/j.jpba.2018.12.045