SR-9009 Stenabolic is a synthetic REV-ERB agonist investigated primarily in laboratory and animal research. It is studied for its effects on circadian signaling, metabolic regulation, inflammation, and exercise-related biology.

Product Information

SR-9009 interacts with REV-ERB nuclear receptors that regulate genes involved in the body's molecular clock. The liquid format represents the formulation of the compound; available research concerns SR-9009 itself rather than a clinically established liquid formulation. SR-9009, also known as Stenabolic, is studied primarily as a REV-ERB agonist in preclinical research.

How It Works

SR-9009 activates REV-ERB receptors and changes transcription of genes involved in circadian and metabolic regulation. These effects can influence energy metabolism and inflammatory signaling in experimental models.

POTENTIAL BENEFITS

1. Circadian Biology Research

REV-ERB activation provides researchers with a way to examine the molecular clock and its relationship with sleep-wake and metabolic processes.

2. Metabolic Pathway Research

SR-9009 has been investigated for effects on lipid and glucose metabolism in animal models, making it relevant to metabolic-signaling research.

3. Exercise & Muscle Research

Preclinical work has examined SR-9009 in relation to exercise tolerance and skeletal-muscle metabolic pathways.

4. Inflammation Research

Research has demonstrated effects on inflammatory signaling, including NLRP3 and cytokine-related pathways in experimental models.

Dosage

There is no established human dosage for SR-9009. Published research uses animal doses under controlled experimental conditions and does not establish an appropriate dose for humans. Formulation into a liquid does not create a validated clinical dosage.

Side Effects

Because human safety data are limited, the full adverse-effect profile is unknown. Altering REV-ERB signaling could potentially affect circadian, metabolic, cardiovascular, and inflammatory systems.

References

1. PubMed — Pharmacological targeting of REV-ERBs
2. PubMed — SR9009 and exercise/metabolic research
3. PubMed — SR9009 and inflammation
4. PubMed — SR9009 and NASH/metabolism

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DMAA, or 1,3-dimethylamylamine, is a synthetic compound that has been used in various applications. Originally introduced as a nasal decongestant, DMAA later found use in different industries. It gained popularity in certain products due to its stimulating properties. While preclinical studies suggest potential benefits for sports performance, it’s crucial to emphasize that these effects must be substantiated through clinical trials.

How 1,4 DMAA Works?

DMAA, or 1,3-dimethylamylamine, is thought to potentially enhance physical performance through its sympathomimetic effects on the sympathetic nervous system. By mimicking neurotransmitters like epinephrine, norepinephrine, and dopamine, DMAA has the potential to trigger a heightened stimulation response that can lead to various athletic performance-related benefits.

One primary mechanism involves the potential increased release of adrenaline and noradrenaline, hormones crucial for the body’s “fight or flight” response. This heightened hormonal release can translate into a faster heart rate, improved oxygen supply to muscles, and increased energy availability. Consequently, test subjects may observe enhanced endurance, heightened alertness, and elevated energy levels. 

Furthermore, DMAA’s sympathomimetic properties may induce vasoconstriction, causing blood vessels to narrow. This effect can enhance blood flow and oxygen transport to muscles, potentially contributing to improved exercise performance and endurance. Additionally, some report a subjective sense of euphoria, which could positively impact motivation and the perceived effort during physical activities. 

Note: It’s essential to acknowledge that the use of DMAA for performance enhancement is a subject of debate, with concerns raised about its safety and efficacy. Due to limited research and potential health risks. BehemothLabz provide DMAA for research; it is not meant for human consumption.

Chemical Properties of 1,4 DMAA

• CAS Number: 105-41-9
• Molar Mass: 115.22 g/mol
• Chemical Structure Formula: C7H17N
• IUPAC Name: 4-methylhexan-2-amine
• Also known by Synonyms as: 1,3-Dimethylpentylamine, 4-methylhexan-2-amine, Methylhexaneamine, Forthane, 1,3 dmaa

Potential Research Applications for 1,4 DMAA Liquid

DMAA and Physical Performance Potential 

There was a recent study in Mainz, Germany, that looked at how common and why people use nutritional supplements (NS) when they go to fitness classes. The study focused on new multi-ingredient supplements like pre-workout boosters (PWBs). Some PWBs, like enhancers like DMAA( geranium plants), N,α-DEPEA, DMAE, and DMBA, may have risks, harms, and benefits that we don’t fully understand yet. Out of the 492 people polled in 13 fitness studios, 57.0% said they had used NS in the last four weeks.

The study shows that using pre-workout boosters (PWBs) is linked to several things, such as gender, training regularity, and the reason for wanting to improve sports performance. This powder, which might contain stimulants like DMAA, is connected to predictor variables like wanting to improve mental focus ability and competing. It is important to remember that these substances are not meant to be eaten. This adds to the ongoing debates in the exercise community about what these supplements might mean for people, as this may lead to adverse events. 

DMAA and Memory Studies

In another study, a dietary supplement containing caffeine and DMAA showed some interesting effects on the central nervous system, particularly in memory and mental speed when taken 30 minutes before testing. Subjects experienced a slight improvement in memory, visual processing speed, and reaction time. However, the changes were not very big, and it’s still unclear if they are important for real-life situations. The study couldn’t figure out if it was the caffeine or the DMAA that was mainly responsible for these effects. Also, researchers haven’t looked specifically at the effects of DMAA by itself on these mental abilities. So, while the results are intriguing, more research is needed to fully understand how DMAA and other ingredients in the supplement might affect mental performance. 

DMAA and Metabolic Research

Recent data suggest that a dietary supplement containing DMAA may play a role in promoting fat loss among 32 healthy test subjects. The study focused on exercise-trained models, revealing that the supplement potentially aids in fat loss without causing adverse effects on resting blood pressure or key safety markers in the blood. It’s noteworthy that while the supplement demonstrated overall safety, a slight increase in resting heart rate was observed. These findings shed light on the potential of DMAA to contribute to weight management without compromising cardiovascular safety. 

Please note that DMAA is intended for research purposes only; it is not meant for human consumption. Further research is still needed to establish statistically significant studies on free fatty acids. 

DMAA and Cholesterol

Previous studies on 1,3-dimethylamylamine have shown that it causes a short-term rise in blood pressure, mostly at the systolic level.  A study with 25 people over 10 weeks found that a supplement with 1,3-dimethylamylamine did not significantly raise their steady heart rate or blood pressure. The supplement only slightly raised systolic blood pressure by about 6 mmHg. Notably, health factors in the blood, such as creatinine and alkaline phosphatase, changed over time, but there were no big differences between the supplement group and the placebo group. A big change in low-density lipoprotein cholesterol (LDL-C) levels showed that the supplement group had a drop of about 7 mg · dL(-1). Please keep in mind that this compound should not be consumed. More research is needed with a longer intervention period, a bigger sample size, and more health and safety measures. 

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Please make sure you go through the Terms and Conditions, and please familiarize yourself with them as they are important. Please research the scientific uses of this product before making any purchases. Make note that the packaging and labels of the product may differ from those shown on the website.

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ATTENTION: All Behemoth Labz products are strictly for LABORATORY AND RESEARCH PURPOSES ONLY. They are not to be used for any human or veterinary purposes.

Reference Links

J Bloomer, R. (2018). 1,3-Dimethylamylamine (DMAA): A Brief History and Review of Anecdotal and Laboratory Findings. Journal of Alternative, Complementary & Integrative Medicine, 4(3), 1–11. https://doi.org/10.24966/acim-7562/100057

Dreher, M., Ehlert, T., Simon, P., & Neuberger, E. W. I. (2018). Boost Me: Prevalence and Reasons for the Use of Stimulant-Containing Pre-Workout Supplements Among Fitness Studio Visitors in Mainz (Germany). Frontiers in Psychology, 9. https://doi.org/10.3389/fpsyg.2018.01134

Powers, M. E. (2015). Acute Stimulant Ingestion and Neurocognitive Performance in Healthy Participants. Journal of Athletic Training, 50(5), 453–459. https://doi.org/10.4085/1062-6050-50.1.07

McCarthy, C. G., Canale, R. E., Alleman, R. J., Reed, J. P., & Bloomer, R. J. (2011). Biochemical and anthropometric effects of a weight loss dietary supplement in healthy men and women. Nutrition and Metabolic Insights, 5, 13–22. https://doi.org/10.4137/NMI.S8566

Ryzhenkov, V. E., Ogurtsov, R. P., Trubacheva, V. V., Popov, V. G., & Puzyreva, V. P. (1988). Effect of thymalin on the development of experimental hyperlipidemia and atherosclerosis. Voprosy Meditsinskoi Khimii, 34(1), 51–56. https://pubmed.ncbi.nlm.nih.gov/2967015/