Alpha has capsulized the ingredients that have combined potential to increase testosterone production. These include well-known substances including D-aspartic acid, tribulus, magnesium, long jack root, and ashwagandha root.
Ingredients per 2 Capsules:
Magnesium (as Magnesium Aspertate)
Long Jack Root
Please note that the packaging of the product you receive may differ from the product image on our website. We sometimes change labeling as we consistently improve and occasionally ship directly from our supplier to fulfill your order faster. Rest assured that the product is the same and of the same quality as advertised.
What is Testosterone
Principal male sex hormone or androgen known as testosterone controls spermatogenesis, male sex characteristics, sex differentiation, and fertility. [R] Testosterone mainly came from cholesterol wherein cholesterol is converted into testosterone by Leydig cells in the testes. [R]
Testosterone regulates the physical traits of men. [R] It is in charge of the growth of male sexual traits like a deeper voice, face and body hair, and more developed muscles. Sperm production and sex drive are two more important functions of testosterone. [R]
Production of Testosterone
The pituitary gland and hypothalamus in the brain control the generation of testosterone. Gonadotropin-releasing hormone (GnRH), which is produced by the brain, stimulates the pituitary gland to release the hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH) into the bloodstream. [R]
As LH reaches the testicles, it stimulates the production of testosterone by specific cells known as Leydig cells. The hormone FSH supports the testicles’ ability to produce sperm. [R]
The hypothalamus and pituitary gland are both part of a feedback loop that controls how much testosterone is produced by the testicles. Low testosterone levels cause the hypothalamus to create more GnRH, which then prompts the pituitary to release more LH and FSH, increasing the synthesis of testosterone. [R]
To convert cholesterol into testosterone, Leydig cells in the testes perform their activity. The earliest stage of this process is regulated by LH. Dehydroepiandrosterone (DHEA) and androstenedione are two crucial intermediates in this procedure. The 17-beta-hydroxysteroid dehydrogenase enzyme converts androstenedione to testosterone. The majority of testosterone is incorporated into plasma proteins such as albumin and sex hormone-binding globulin.
The body receives an excess of testosterone hormone from this majority source of protein-bound testosterone. The prostate gland, seminal vesicles, bone, and muscle are the main tissues that are affected by the trace levels of free testosterone in the blood. The biological enzyme 5-alpha-reductase transforms testosterone into dihydrotestosterone. In order to control the expression of proteins, testosterone, and dihydrotestosterone can attach to cell receptors. [R]
Overproduction, underproduction, receptor insensitivity, or poor testosterone metabolism are all examples of pathology connected to testosterone. [R]
Age, some drugs, chemotherapy, diseases of the hypothalamus-pituitary axis, intrinsic hypogonadism, cryptorchidism, orchitis, and hereditary conditions including Klinefelter and Kallmann syndrome can all cause decreased testosterone production. [R]
The effect of the amount of androgen including testosterone varies widely. [R] In this study [R], it aimed to determine the physiological consequences of various levels of testosterone and estradiol in healthy male test models aged 20 to 50 years. The researchers provided goserelin acetate to suppress endogenous testosterone and estradiol and then randomly assigned the male test models to receive a placebo gel or different doses of testosterone gel, with or without anastrozole to suppress the conversion of testosterone to estradiol.
The primary outcomes assessed were changes in the percentage of body fat and in lean mass, while secondary outcomes included subcutaneous and intra-abdominal fat areas, thigh-muscle area and strength, and sexual function.
The study found that the amount of testosterone required to maintain lean mass, fat mass, strength, and sexual function varied widely among male test subjects. Lean mass, muscle size, and strength declines were predominantly caused by androgen deficit, whereas body fat percentage increases were primarily caused by estrogen shortage. Both flaws were a factor in the loss of sexual function.
Overall, the findings suggest that the current approaches to diagnosing testosterone deficiency do not consider the physiological consequences of various testosterone and estradiol levels, and the evaluation and management of hypogonadism in male test subjects need to be reconsidered.
Alpha is composed of a few essential components as mentioned above. Here is a list of some of the main research findings about the various ingredients:
Long Jack Root
Scientifically known as Eurycoma longifoli, Long Jack or also known as Tongkat Ali is a herbal supplement made from the roots of a Southeast Asian tree. It has historically been used to cure a number of ailments, such as decreased libido, stress, and weariness. Although there is scant and inconsistent scientific support for these claims, long jack may have the potential to raise testosterone levels and improve male sexual function. [R]
Eurycomanone, eurycomanol, eurycomalactone, canthine-6-one alkaloid, 9-hydroxycanthine-6-one, β-hydroxyklaineanone, phenolic components, tannins, quanissoids, and triterpenes are some of the chemical substances that have been identified specifically from the roots of Long Jack. Several substances have shown to offer therapeutic benefits, including anticoagulant properties for problems after childbirth, aphrodisiac, antimalarial, antibacterial, anticancer, anxiolytic, and antiulcer properties. Moreover, ElJ’s high superoxide dismutase concentrations have been linked to its antioxidative capabilities. Because of its capacity to potentially enhance the production or activity of androgen hormones, particularly testosterone, Long Jack root is well known for its aphrodisiac effects. [R]
Moreover, studies on test subjects have shown that supplementing with Long Jack root potentially raised testosterone levels. [R,R]
In addition, supplementation was also safe because it did negatively impact the liver and renal functions at this dosage and for 6 weeks, increased serum testosterone and enhanced test subject muscle strength. [R]
Tribulus or scientifically known as Tribulus terrestris (TT) is a caltrop-family annual plant with little woody fruits that have long, sharp spines. Due to their phytochemical and pharmacological properties, the plant’s root and fruit have both been utilized medicinally in traditional Chinese and Ayurveda medicine. [R]
Its many portions include a range of chemical components that are crucial for medicine, including alkaloids, steroidal saponins, flavonoids, and flavonol glycosides. It has diuretic, aphrodisiac, antiurolithic, immunomodulatory, antidiabetic, absorption enhancing, hypolipidemic, cardiotonic, central nervous system, hepatoprotective, anti-inflammatory, analgesic, antispasmodic, anticancer, antibacterial, anthelmintic, larvicidal, and anticariogenic activities. [R]
Terrestris is said to be an aphrodisiac and was tested on various test subjects. Bolus intravenous injection of the TT extract at doses of 7.5, 15, and 30 mg/kg body weight, found that protodioscin (PTN) induced a moderate increase in testosterone, dihydrotestosterone, and dehydroepiandrosterone sulfate levels in primates. Additionally, after TT extract administration orally for 8 weeks at doses of 2.5, 5, and 10 mg/kg body weight, it improved libido, sexual activity, and intracavernous pressure in rats. It also had a pro-erectile effect on the corpus cavernosum smooth muscle of rabbits after TT extract administration orally for 8 weeks at doses of 2.5, 5, and 10 mg/kg body weight. The biological aphrodisiac activity is attributed to protodioscin and protogracillin, the two major constituents of the saponin fraction from TT. [R]
Only animal studies on the toxicity of TT have been done. For mice, it was determined that the dose corresponding to the LD 50 is 813 mg/kg [R]. Native goats and sheep showed signs of significant cardiac muscle, liver, and kidney damage when their daily diets consisted of 80% fresh plants [R;R]. A young man who drank a large dose of TT over the course of two days to avoid kidney stone formation was the only person to have acute TT poisoning as recorded. After seven days in the hospital, his biochemical signs of kidney necrosis and hepatitis subsided [R].
The botanical name for ashwagandha is Withania somnifera Dunal, and it belongs to the Solanaceae family of plants. It is also referred to as winter cherry or Indian ginseng. The word “Ashwagandha” means “horse smell” in its literal sense. The herb’s name derives from two factors. One explanation is that the herb’s fresh roots give forth a horsey odor. The second reason is that it is widely believed that a person who consumes the herb’s extracts could acquire strength and energy like those of a horse. This herb occupies a key position in Ayurvedic treatment. A “royal herb,” ashwagandha is known for its numerous rejuvenating potential properties on the human body. [R]
A variety of pharmacologically and medicinally significant alkaloids, including withanolides, sitoindosides, and other components, are present in ashwagandha. [R]
Adaptogenic, antioxidant, anticancer, anxiolytic, antidepressant, cardioprotective, thyroid- and immune-modulating, antibacterial, antifungal, anti-inflammatory, neuroprotective, cognitive-improving, and hematopoietic agents have all been explored for this herb. [R]
The possible impact of ashwagandha on male testosterone levels has been studied in many studies.
One study investigated the effects of ashwagandha on fatigue, vigor, and steroid hormones in overweight test subjects aged 40-70 with mild fatigue. The 16-week, randomized, double-blind, placebo-controlled, crossover study found that ashwagandha intake was associated with an 18% greater increase in dehydroepiandrosterone sulfate (DHEA-S) and 14.7% greater increase in testosterone compared to the placebo. Nevertheless, cortisol, estradiol, weariness, vitality, or sexual well-being did not differ significantly between groups. Further studies with larger sample sizes are needed to confirm these findings. [R]
Another pilot study evaluated the effect of Ashwagandha root extract on spermatogenic activity in oligospermic test subjects. 46 male test subjects with oligospermia were randomized to receive either Ashwagandha extract or placebo for 90 days. The study found that Ashwagandha treatment resulted in a significant increase in sperm count, semen volume, and sperm motility compared to placebo. Additionally, the treatment group showed significantly greater improvement and regulation in serum hormone levels. These findings suggest that Ashwagandha extract may have therapeutic value in the treatment of oligospermia leading to infertility. [R]
Androgen effects were exhibited for a period of three months, rats in the Ashwagandha-treated group had significantly higher body weights than those in the control group. [R] Furthermore, another study investigated the effects of ashwagandha root extract on muscle mass and strength in healthy young test subjects engaged in resistance training. The 8-week randomized, double-blind, placebo-controlled clinical study involved 57 male subjects who were randomized into treatment and placebo groups. The control group took a placebo, whereas the treatment group took 300 mg of ashwagandha root extract twice daily. The results of the study showed that when compared to the placebo group, the ashwagandha-treated group dramatically improved muscle strength and size, decreased exercise-induced muscle damage, increased testosterone levels, and reduced body fat percentage. According to the study, using ashwagandha supplements along with resistance exercise may be beneficial. [R]
In an acute toxicity study, LD50 in an investigation on acute toxicity was discovered to be 1,750 mg (p.o.) in albino mice. [R]
Stinging Nettle (SN)
Urtica dioica L., also referred to as stinging nettle, is a perennial herbaceous wild flowering plant. Stinging nettle can be found in North America, Europe, Asia, and North Africa. It is a plant with edible, medicinal, and nutritional qualities. Stinging nettle leaves are used to treat arthritis, rheumatism, and allergic rhinitis, while the root is utilized to treat fictional issues related to benign prostatic hyperplasia. Its leaves are rich in antioxidants like polyphenols and carotenoids as well as fiber, vitamins, minerals, and antioxidant components like polyphenols and carotenoids. [R]
Among the primary chemical components of SN are flavonoids, tannins, volatile chemicals, fatty acids, polysaccharides, isolectins, sterols, terpenes, proteins, vitamins, and minerals [R]. Provitamin A and vitamin C are both abundant in it [R]. About 30% of dry mass is made up of protein, which contains several amino acids essential to humans. Almost 20% of the dry bulk is made up of minerals. There is a lot of zinc, iron, cobalt, potassium, nickel, and molybdenum [R].
In one study, it was discovered that stinging nettle root extract might bind to SHBG, a protein that binds to testosterone and lowers its availability in the body. Stinging nettle root extract increased the body’s supply of free, accessible testosterone via binding to SHBG. [R]
However, a contradictory study was published. One randomized, double-blind, placebo-controlled, partial-crossover study was carried out to investigate the effects of a stinging nettle root extract on testosterone levels. The extract was produced from the roots using a fractional percolation procedure and standardization (60). Among 620 test subjects with lower urinary tract symptoms and a mean age of 63 years (intervention group: 64.0 y; control group: 62.0 y), daily treatment with 360 mg of stinging nettle root extract for six months did not substantially raise testosterone concentrations in comparison to the placebo group. [R]
Invertebrate and vertebrate neuroendocrine tissues contain D-aspartic acid (D-Asp), which performs crucial physiological roles. D-Asp is thought to be a testosterone booster for infertile men as well as for athletes to increase muscle development and strength according to recent reports suggesting it is involved in the synthesis and release of testosterone. [R]
A study suggested testosterone production effects to test subjects.
One study investigated the effect of D-aspartic acid (D-Asp) on the release of luteinizing hormone (LH) and testosterone in test subjects and rats, as well as its role in their synthesis in the pituitary and testes of rats. A group of test subjects and rats were given a daily dose of D-Asp for 12 days, and LH and testosterone accumulation was determined in their serum. The results showed that D-Asp induces an enhancement of LH and testosterone release in test subjects and rats. The study also found that D-Asp increases the synthesis and release of LH in the pituitary gland through cGMP as a second messenger, and testosterone in the Leydig cells of the testes through cAMP as a second messenger. Overall, the study suggests that D-Asp has a role in the regulation of the release and synthesis of LH and testosterone in test subjects and rats. [R]
The body requires magnesium as a vitamin to remain healthy. Many biological processes, including the synthesis of protein, bone, and DNA as well as the regulation of blood pressure, blood sugar levels, muscle, and neuron function, depend on magnesium. [R]
A person needs different amounts of magnesium depending on their age and gender. A typical daily suggested dosage in milligrams (mg) for adult men is around 400-420. [R]
Recent studies have investigated the biomolecular interactions between testosterone (T), sex hormone-binding globulin (SHBG), and magnesium using high-performance liquid chromatography (HPLC). These studies provide evidence that changes in magnesium levels within the biological serum concentration range could enhance the availability of bioavailable testosterone (Bio-T) by altering the T-SHBG affinity. Magnesium binds to SHBG in a nonspecific mode, leading to uncompetitive inhibition with T in binding SHBG and enhancing Bio-T availability. SHBG is a homodimer that contains metal-binding sites, including magnesium, supporting the role of magnesium in modulating T bioactivity at a molecular level. In vitro studies have also shown that adequate magnesium concentrations can displace T from its test subject’s serum albumin (HSA) binding site, suggesting an opportunity for testing in vivo the effects of magnesium supplementation during DHEA treatment on the Bio-T rate. [R]
Another study investigated the effects of magnesium supplementation and exercise on free and total plasma testosterone levels in sedentary individuals and tae kwon do athletes. The study found that supplementation with 10 mg of magnesium per kilogram body weight for four weeks increased free and total testosterone levels in both sedentary individuals and athletes. The increase was higher in athletes than in sedentary individuals. Exercise also increased testosterone levels compared to resting levels and to sedentary subjects. The study suggests that magnesium supplementation may have potential benefits for testosterone levels in both sedentary and athletic populations. [R]
Frequently Asked Questions (FAQs)
What is a dietary supplement?
According to FDA, the Dietary Supplement Health and Education Act (DSHEA) of 1994 defines a dietary supplement as a product intended for ingestion that contains a dietary ingredient intended to supplement the diet, including vitamins, minerals, herbs or botanicals, amino acids, probiotics, and other dietary substances. These supplements can come in various forms such as pills, tablets, capsules, liquids, and powders, and must be labeled as such. They are considered a special category under the umbrella of “foods” unless they are labeled as drugs. [R]
What is a dietary ingredient?
A product meant for consumption that contains a “dietary ingredient” meant to augment the diet is referred to as a dietary supplement. “Dietary components” that are naturally found in food, such as amino acids, enzymes and live microbes (commonly referred to as “probiotics”), vitamins and minerals, herbs and other botanicals, as well as concentrates, metabolites, constituents, extracts, or combinations of any dietary ingredient are all included under the term “dietary ingredient.” [R]
Does FDA authorized to approve dietary supplements before marketed?
The Federal Food, Drug, and Cosmetic Act was revised in 1994 by the Dietary Supplement Health and Education Act (DSHEA), which changed the FDA’s ability to regulate dietary supplements. The DSHEA prohibits the FDA from approving dietary supplements for efficacy and safety prior to their marketing. In many instances, businesses can legally launch dietary supplements on the market without even informing the FDA. [R]
How age affects testosterone production?
Typically, a man’s testosterone production peaks in adolescence and the early years of maturity, then slowly drops with age. [R]
What are other factors to affect testosterone production?
Certain medical condition, such as hypogonadism or testicular cancer, as well as aspects of daily living, such as stress, food, and exercise, can also have an impact on testosterone production. [R]
Do women have testosterone too?
Women have testosterone too but in much smaller amounts than in men. [R]
Where to Buy Alpha Capsule for Sale?
Behemoth Labz is the best place to buy Alpha online offering the best prices
If you’re looking to purchase Alpha capsules, It is recommended to search online for reputable sellers. Equipped with the knowledge of what to look for in a reliable supplier, you can find great deals on Alpha capsules without breaking the bank.
For example, the highly recommended Behemoth Labz has been in business since 2014 and offers a range of high-quality research chemicals, including Alpha capsules. They offer the best product and have a great reputation for customer service.
While purchasing research chemicals can be hard and expensive, it’s important to read up on the product and supplier before making a purchase to ensure that you’re getting the best purity product. With the right research, you can find great price on Alpha capsules with Behemoth Labz
Handling and Storage
Keep out of the reach of children and keep at room temperature in a dry, cool environment.
Alpha Capsule is a supplement that aims to increase testosterone production. It contains active ingredients such as D-aspartic acid, tribulus, magnesium, long jack root, stinging nettle, and ashwagandha root. Testosterone is the principal male sex hormone that regulates male physical traits, sperm production, and sex drive.
Long Jack root has been shown to raise testosterone levels, and supplementation is safe. Tribulus has diuretic, aphrodisiac, and other properties, and it is said to be an aphrodisiac. The biological aphrodisiac activity of Tribulus is attributed to protodioscin and protogracillin. Ashwagandha Root is also included, which is a plant with potential benefits for anxiety, stress, and inflammation. Stinging Nettle, on the other hand, is a perennial herbaceous wild flowering plant that has edible, medicinal, and nutritional qualities. Its leaves are rich in antioxidants, fiber, vitamins, minerals, and protein. Stinging nettle root extract might bind to SHBG, a protein that binds to testosterone and lowers its availability in the body. However, a contradictory study has been published. D-Aspartic acid has been reported to be involved in the synthesis and release of testosterone. Recent studies have shown that magnesium can enhance the availability of bioavailable testosterone by altering the T-SHBG affinity. Magnesium supplementation may have potential benefits for testosterone levels in both sedentary and athletic populations.
All mentioned above are key ingredients that have shown effects on testosterone levels in test subjects.
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