Identification of evodiamine as the bioactive compound in evodia (Evodia rutaecarpa Benth.) fruit extract that activates human peroxisome proliferator-activated receptor gamma (PPARγ)
Chem compound extracted from the genus Tetradium plant, and has been shown to reduce fat uptake in rodent studies. Suspected that its acion mechanism action is similar to that of capsaicin. As such, it has been included in some dietary supplements. Neither its fat-burning effects in humans nor any potential side effects have been empirically established.
It acts primarily as a thermogenic and stimulant. Evodiamine may also act in a manner comparable to tianeptine by increasing the number of serotonin transporters available in the brain, enhancing the reuptake of serotonin.
Selective Androgen Receptor Modulators (SARMs) – therapeutic compounds with similar properties to anabolic agents, but with reduced androgenic properties. They have advantage of androgen-receptor specificity, tissue selectivity, and lack of steroid-related side effects.
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