LGD 4033 Ligandrol (Liquid Form) – Product Details

Ligandrol is a selective androgen receptor modulator (SARM) that binds to androgen receptors. In a clinical study involving 76 healthy men, Ligandrol was able to suppress triglyceride levels and increase lean body mass in a dose-dependent manner. [R]

In animal models, LGD-4033 has demonstrated anabolic activity in the muscle. This SARM has also showcased anti-resorptive and anabolic activity in bone. Animal models have established that Ligandrol has robust selectivity for muscle vis-à-vis prostate. [R]

Behemoth Labz sells Ligandrol for laboratory research use only.

We also carry Ligandrol capsules and injectable Ligandrol if you’re looking for those instead.

• CAS Number is stated as 1165910-22-4
• Molar Mass is 338.253 g·mol−1
• It has a Chemical Formula of C14H12F6N2O
• IUPAC Name is 4-[(2R)-2-[(1R)-2,2,2-trifluoro-1-hydroxyethyl]pyrrolidin-1-yl]-2-(trifluoromethyl)benzonitrile
• Also known by Synonyms as VK5211; LGD-4033

The Ligandrol for sale from Behemoth Labz is 3rd party tested for the utmost purity.

What is Ligandrol?

Ligandrol, or LGD-4033, is a non-steroidal SARM. SARMs are small molecule drugs that selectively bind to androgen receptors in the body. Their selective action enables SARMs to stimulate cellular anabolic activity while avoiding the side effects of anabolic steroids. [R]

Ligandrol was initially developed as a potential treatment for muscle wasting. In its first clinical trial, Ligandrol increased muscle mass without raising fat mass and suppressed total testosterone, triglyceride, and high-density lipoprotein cholesterol levels in adults. [R]

A subsequent phase 2 clinical study showed Ligandrol dose-dependently increasing walking distance in patients recuperating from a hip fracture. Aside from that, LGD-4033 stimulated significant dose-dependent increases in lean body mass compared to placebo. [R]

Finally, in an ovariectomized rat model, Ligandrol treatment was associated with improved muscle tissue, higher muscle weight and, intramuscular fat content.

 

How does Ligandrol Work?

Research has shown that Ligandrol mimics the activity of testosterone in the body. It does that by binding to androgen receptors (ARs) in the skeletal muscle. In animal models, LGD-4033 has demonstrated robust selectivity for ARs in the muscle versus the prostate. [R]

Its working mechanism distinguishes LGD-4033, as well as other SARMs, from steroids. While SARMs mainly bind receptor sites on the skeletal muscle, steroids target ARs in the entire body. This makes steroids less tissue-selective in their action than SARMs.

 

Ligandrol Research

Multiple human trials and animal studies have been conducted on Ligandrol. These have shown that Ligandrol could increase muscle mass, boost energy levels, and enhance performance. In addition, this SARM has been shown to potentially suppress triglycerides in humans.

 

Ligandrol and Lean Body Mass

In a clinical trial involving 76 healthy men (ages 21-50), Ligandrol administrated was associated with a dose-dependent increase in lean body mass. Unfortunately, the mechanisms by which Ligandrol increased lean body mass remained incompletely understood. [R]

A subsequent phase 2 clinical study demonstrated similar results. The study involved older adults and found that Ligandrol treatment increased lean body mass but not fat mass. Placebo-adjusted increases in lean body mass were 4.8% at 0.5mg and 9.1% at 2mg dose. [R]

Furthermore, in an ovariectomized female rat model, Ligandrol and Ostarine were shown to increase muscle growth and physical function. Both these SARMs were found to have beneficial effects on muscle structure, metabolism, and vascularization. [R]

 

Ligandrol and Fat

In the above phase 1 clinical trial, Ligandrol was found to stimulate a dose-dependent decrease in triglyceride levels in the LGD-4033 group. Furthermore, only one dose was able to increase lean body mass, the decrease in triglyceride levels was across all doses.

Similar results were obtained in the phase 2 clinical study. Patients receiving LGD-4033 experienced a dose-dependent decrease in mean fat mass following 12 weeks of treatment. This shows that Ligandrol stimulated beneficial changes in overall body composition.

 

Ligandrol and Bone Density

LGD-4033 has been shown to increase bone mineral density, bone formation, and bone strength in preclinical models. Data from these models show that Ligandrol also increased bending strength (an indicator of resistance to fracture) in osteopenic female rats. [R]

Statistically significant improvements in bone mineral density were observed after 12 weeks of administering LGD-4033. These improvements were observed at doses as low as 0.03 mg/kg/day in cortical bone and 0.3mg/kg/day in cancellous bone. [R]

 

Ligandrol and Leg Press Strength

An enhanced leg press strength is an indicator of above-average endurance, strength, and lower body stability. An increased leg press strength can also give knees the ability to manage heavier free weights.

A 21-day randomized, placebo-controlled, ascending dose trial was conducted to investigate the potential effects of LGD-4033 in healthy young men. Results from the trial show that Ligandrol was well-tolerated and produced dose-dependent gains in leg press strength. [R]

 

 

Ligandrol Side Effects

A three-week study involving healthy young men demonstrated that Ligandrol administrated was associated with a dose-dependent suppression in HDL cholesterol levels. Furthermore, the LGD-4033 group experienced greater HDL cholesterol reduction than the placebo group.

Recently, there have been reports of two cases of liver injury in young men who used Ligandrol and/or Ostarine for a few weeks. Acute liver injury occurred in both cases after stopping SARMs while on PCT. The patients recovered from the condition after three months. [R]

 

Frequently Asked Questions

What is the half-life of LGD 4033?

LGD-4033 demonstrated a prolonged elimination half-life of 24-36 hours in phase 1 clinical study. Researchers conducting the study claimed that its prolonged elimination half-life renders LGD-4033 amenable to once daily or even a less frequent regime.

 

Is LGD-4033 legal?

Ligandrol is on the Prohibited List annually released by the World Anti-Doping Agency (WADA). The US Food and Drug Administration (FDA) hasn’t approved LGD-4033 for human clinical use. Behemoth Labz sells Ligandrol for lab research use and not for human consumption.

 

Does LGD-4033 suppress endogenous testosterone?

In the above placebo-controlled clinical trial, LGD-4033 administration stimulated a dose-dependent suppression of total testosterone and sex-hormone binding globulin. However, both these hormones returned to baseline values by day 56 of the study.

 

Where to Buy Ligandrol for Sale?

Behemoth Labz is the best place to buy Ligandrol LGD-4033 online.

We have been around since 2014, supplying the highest-quality research compounds money can buy. All of our products come with a 100% satisfaction guarantee, free shipping, and a money-back guarantee. We carry Ligandrol liquid, injectable Ligandrol, and Ligandrol capsules.

 

Ligandrol Summary

Ligandrol has been shown to increase lean muscle mass, leg press strength, and fat content in multiple human trials. This non-steroidal SARM has also been found to increase muscle tissue, bone mineral density, and bone strength in preclinical animal models

 

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