Finasteride

Product Details - Finasteride

Finasteride is a synthetic compound classified as a selective inhibitor of the enzyme 5-alpha reductase. Structurally, it belongs to a group of steroidal compounds designed to interact with enzymes involved in androgen metabolism. Within controlled research environments, it is commonly examined for its ability to modulate biochemical pathways associated with the conversion of testosterone into downstream metabolites.

In addition, the compound is often referenced in studies focusing on enzyme kinetics and competitive inhibition, as its structure allows it to bind with high affinity to specific isoforms of 5-alpha reductase.

Mechanism of Action

Finasteride functions through the selective inhibition of the enzyme 5-alpha reductase, which catalyzes the conversion of testosterone into dihydrotestosterone (DHT). By associating with the enzyme’s active site, the compound forms a stable enzyme-inhibitor complex that reduces catalytic efficiency.

More specifically, finasteride exhibits a higher binding affinity for type II 5-alpha reductase isoenzymes, leading to a measurable decrease in DHT synthesis at the molecular level. This reduction influences androgen-dependent signaling pathways by altering ligand availability for androgen receptors.

As a consequence, downstream processes such as receptor activation, nuclear translocation, and gene transcription may be modulated. These molecular interactions make finasteride a useful reference compound in studies examining steroid-regulated gene expression and enzymatic control mechanisms.

Chemical Properties of Finasteride

Property	Value
Product Name	Finasteride
CAS Number	98319-26-7
Molar Mass	372.55 g/mol
Chemical Formula	C23H36N2O2
IUPAC Name	(1S,3aS,3bS,5aR,9aR,9bS,11aS)-N-tert-butyl-9a,11a-dimethyl-7-oxo-2,3,3a,3b,4,5,5a,6,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-1-carboxamide

Research Applications

Enzyme Inhibition Studies

Finasteride is frequently utilized in experimental models investigating enzyme-substrate dynamics involving 5-alpha reductase. Its ability to form a stable inhibitory complex allows researchers to analyze catalytic suppression, binding affinity, and inhibition constants under controlled conditions.

Androgen Pathway Analysis

This compound is also applied in studies exploring androgen metabolism and regulatory signaling networks. By altering the enzymatic conversion of testosterone to DHT, it enables observation of changes in ligand-receptor interactions, including androgen receptor binding behavior and downstream transcriptional activity.

Steroid Metabolism Research

Finasteride supports investigations into steroidogenic pathways by serving as a tool to modulate dihydrotestosterone synthesis. This allows for closer examination of feedback regulation, enzyme expression patterns, and metabolic flux within androgen-related biochemical systems.

Isoenzyme Selectivity Research

Due to its preferential interaction with specific isoforms of 5-alpha reductase, finasteride is often used to differentiate isoenzyme activity. This makes it valuable in comparative studies analyzing structural variations, binding specificity, and functional differences between enzyme subtypes.

Why Choose BehemothLabz to Buy Finasteride for Research

BehemothLabz supplies research-grade Finasteride produced under controlled laboratory conditions with strict quality assurance protocols in place. Each batch undergoes detailed analytical verification to ensure consistency in molecular composition and purity.

In addition, comprehensive documentation, including laboratory testing reports and sourcing transparency, supports reproducibility across experimental applications. BehemothLabz maintains a compliance-focused approach, ensuring that all compounds are supplied exclusively for laboratory-based investigation and analytical research.

Disclaimer

Finasteride is intended strictly for laboratory research and analytical purposes only. It is not designed for diagnostic procedures, therapeutic applications, or any form of in vivo study.

All references to biochemical pathways, receptor interactions, and enzymatic processes are provided solely within a research context. This compound must be handled only by qualified professionals within controlled laboratory environments, in accordance with applicable regulations and safety standards.

Any use outside of these defined research conditions is strictly prohibited.

References

• Gupta, A. K., Talukder, M., & Williams, G. (2022). Comparison of oral minoxidil, finasteride, and dutasteride for treating androgenetic alopecia. The Journal of dermatological treatment, 33(7), 2946–2962. https://doi.org/10.1080/09546634.2022.2109567 
• Piraccini, B. M., Blume-Peytavi, U., Scarci, F., Jansat, J. M., Falqués, M., Otero, R., Tamarit, M. L., Galván, J., Tebbs, V., Massana, E., & Topical Finasteride Study Group (2022). Efficacy and safety of topical finasteride spray solution for male androgenetic alopecia: a phase III, randomized, controlled clinical trial. Journal of the European Academy of Dermatology and Venereology : JEADV, 36(2), 286–294. https://doi.org/10.1111/jdv.17738 

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