Sterile Water

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Sterile Water for Injection is a sterile, nonpyrogenic, preservative-free water preparation used as a diluent or solvent for compatible injectable medications. Unlike Bacteriostatic Water, it contains no antimicrobial preservative.

Product Information

Current DailyMed labeling describes Sterile Water for Injection as sterile, nonpyrogenic water containing no bacteriostat, antimicrobial agent, or added buffer. It is supplied in single-dose containers and is intended to dilute or dissolve drugs that require an aqueous vehicle.

How It Works

Sterile Water provides a clean aqueous vehicle for compatible medications requiring dissolution or dilution. It has no active pharmacological effect itself.

POTENTIAL BENEFITS

1. Provides a Preservative-Free Diluent

Sterile Water contains no benzyl alcohol or other antimicrobial preservative. This makes it useful when a medication specifically requires a preservative-free diluent.

2. Supports Injectable Medication Preparation

Sterile Water is used as a pharmaceutical solvent or diluent for compatible medications. The exact amount and suitability depend on the medication's official preparation instructions.

3. Provides a Sterile, Nonpyrogenic Vehicle

The product is manufactured as sterile and nonpyrogenic Water for Injection. This makes it suitable for controlled pharmaceutical preparation when used according to labeling.

4. Useful When Preservatives Are Inappropriate

Because Sterile Water does not contain benzyl alcohol, it can be selected when a preservative-free diluent is specifically required.

Dosage

Sterile Water has no independent therapeutic dosage. The volume used is determined by the medication being prepared and its official instructions. Importantly, the current DailyMed label states that Sterile Water for Injection should only be used after addition of drugs requiring dilution or dissolution and must be made approximately isotonic when intended for IV injection.

Side Effects

Sterile Water must not be administered intravenously by itself because its hypotonic nature can cause hemolysis. Other risks depend on the medication being prepared and the resulting solution.

References

1. U.S. National Library of Medicine. Sterile Water for Injection, USP - Official DailyMed Label. PubMed

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