Guide to S23 SARM: Uses, Benefits, and Side Effects

Time to revolutionize your research! Enter the world of SARMs, specifically the potent S23 SARM, which is gaining attention for its powerful effects. It is designed to improve muscle growth, enhance performance, and aid fat loss while minimizing unwanted side effects during clinical research.

Besides its potential benefits, S23 has shown fewer androgenic effects on subjects. From gym enthusiasts to bodybuilders aiming for peak performance, S23 offers a cutting-edge approach to achieving fitness research goals.

Whether you want to uncover its benefits, dosages, uses, or potential risks, this guide explores everything you need to know about S23 SARM.

What is S23 SARM?

S23 is one of the potent and strongest selective androgen receptor modulators (SARMs). It is made by altering and modifying the chemical structure of less efficacious SARM C-6. In this modification, the para-nitro group of C-6 is replaced by the cyano group.

With strong binding affinity, S23 has 96% bioavailability, the highest among all SARMs. Due to this, its absorption rate is also high when administered orally to subjects. Being a full agonist, it may be very suppressive which is why it is often followed by robust post-cycle therapy (PCT) in research contexts.

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Historical Background of S23

As a potent SARM, S23 was initially developed by pharmaceutical companies while searching for the treatment of muscle-wasting diseases and certain types of cancers.  In today’s world, it has become well-known due to its potential benefits in muscle-gaining and strength improvements on subjects. 

How Does S23 SARM Work?

S23 works by selectively targeting androgen receptors in muscle and bone tissues of test subjects. This selective binding may increase protein synthesis to bulk up muscles and improve bone health. These benefits in research subjects are caused without negatively impacting other parts. Other than that, S23 has a very high binding affinity with a Ki of ∼1.7 nM which is two times higher than C-6.  

Uses of S23 SARM

Having potential benefits, S23 is highly used in investigational research studies. Some of its uses are given below.

• Treatment studies: S23 is generally used to study the treatment of certain medical conditions such as muscle wasting diseases and cancer.
• Contraceptive research: Being researched for potential use as a male contraceptive due to its suppressive effects on testosterone and sperm production.
• Studying potential benefits: With high anabolic effects, it is often used to study its potential benefits like muscle building, loss of fats, and improving bone health. 

Benefits of S23 SARM

Current research has shown various lucrative benefits of S23 for test subjects. Some of the potential benefits of S23 are given below. 

1. Muscle Mass

Being orally active SARM, it has strong anabolic effects on muscle gain as shown in preclinical profiling. When paired with proper nutrition and exercise, it may significantly improve muscle mass. This makes it a popular choice for muscle bulking when research studies require it. [1]

2. Fat Loss

In addition to muscle-gaining benefits, S23 may help with reducing extra body fats in a dose-dependent manner. With fat-burning effects, it has been shown to have fat-reduction properties for gaining a leaner physique during research studies. In general, S23 may help with fat loss indirectly. With increasing basal metabolic rate, S23 may increase energy expenditure which leads to fat loss for energy consumption. [2]

3. Strength and Performance 

Subjects have also reported a significant increase in strength and performance with S23 during clinical investigations. Being anabolic SARM, it may increase 50 lbs of strength over the cycle of its use in research subjects. [3]

4. Bone Health 

S23 can be a good choice for enhancing bone mineral density in subjects. Some of the research studies suggest that it may be beneficial for treating diseases like osteoporosis by strengthening bone density. However, further research is needed to justify this benefit. [3]

Results of S23 SARM

S23 has proven effective for muscle gain, fat reduction, and enhancing strength in test subjects. Research shows that it may lead to an increase of 15–20 pounds over the 8-week cycle. Similarly, some other clinical investigations have shown a 5% decrease in the subject’s body fats when S23 is used for 2 months. These results suggest that S23 is the best choice for research studies. 

S23 SARM Side Effects

Although S23 is generally considered safe for research studies, there are still some side effects associated with its use on test subjects. Some of the unwanted effects include testosterone suppression, night sweats, liver stress, increased aggression, headache, nausea, and irritability. However, these effects may differ and depend on the dosage, the subject’s health condition, and frequency. 

S23 SARM PCT Guidelines 

Due to the high potency of S23, hormone suppression may occur during research studies. This deficiency was also seen in a research conducted on rats. However, it can be counteracted with the help of post-cycle therapy. To mitigate the side effects, researchers often follow a 4 weeks PCT with Clomid. While using the same method and duration of PCT, researchers successfully restored the natural hormonal levels of test subjects. 

Conclusion 

S23 is a powerful SARM that may help improve muscle mass and enhance strength in test subjects. It is potentially used in investigational studies of muscle gain, fat loss, and strength enhancement. Being potent, S23 may be associated with some side effects that may be mitigated with PCT. Unlike steroids, S23 has high anabolic effects and fewer androgenic effects. This makes it a popular choice for clinical studies where anabolic effects on muscles and bone are needed. Consider S23 for optimal and effective results in your research studies.

FAQs

What is the best place to buy S23 SARM online?

Are you interested in studying S23? Consider buying S23 online from BehemothLabz, as it not only ensures the best quality but also provides pure products. Being a reliable vendor, it provides high-quality products for research investigations. Behemoth Labz offers products that can deliver effective and optimal results during research studies. For 100% customer satisfaction, it also ensures trusted and reliable services.

Is S-23 good for strength in research subjects?

Yes, S23 is good for enhancing strength in subjects. Being a potent SARM, S23 may help improve the strength of the test participants.

What is the half-life of S23 in research subjects?

The half-life of S23 is 12 hours in research subjects. This suggests that half of S23 will be eliminated from the system within 12 hours.

What are the other names of S23 SARM?

Other names of S23 SARM are (+)-S-23 and CCTH-methylpropionamide.

Is S23 safe to use in research settings?

Yes, S23 is generally safe to be used in research studies for improving muscle mass and increasing strength.

Does S23 work in research subjects?

Yes, S23 works by selectively targeting androgen receptors in muscles and bones. With this, it may promote muscle-building and improve bone health.

References 

1. Thevis, Mario, et al. “Characterization of in vitro generated metabolites of the selective androgen receptor modulators S‐22 and S‐23 and in vivo comparison to post‐administration canine urine specimens.” Drug testing and analysis 2.11‐12 (2010): 589-598.
2. Cutler, Charlotte, et al. “Detection of the selective androgen receptor modulator S‐23 and its metabolites in equine urine and plasma following oral administration.” Drug Testing and Analysis (2024).
3. Machek, Steven B., et al. “Considerations, possible contraindications, and potential mechanisms for deleterious effect in recreational and athletic use of selective androgen receptor modulators (SARMs) in lieu of anabolic androgenic steroids: A narrative review.” Steroids 164 (2020): 108753.