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Product Details: Adamax

What is Adamax?

Adamax is a synthetic peptide marketed as a structurally modified derivative of Semax (an adrenocorticotropic hormone fragment analogue), with a claimed adamantane modification intended to increase lipophilicity and blood-brain-barrier penetration relative to Semax. It is supplied as a 5mg lyophilized powder.

Identity Caveat (Important): Unlike other compounds in this catalog, Adamax does not have a single, independently verifiable chemical identity. No PubChem CID or registered CAS number is publicly documented for it. Vendor listings disagree on the exact amino acid sequence  reported variously as Ac-MEHFPGPAG-NH2, Ac-MEHFPGP-AG-NH2, and Ac-MEHFPGP-Ad-NH2 ("provisional, pending full disclosure" per one source)  and molecular weight estimates vary by vendor (commonly cited as approximately 1,100–1,300 g/mol, "depending on adamantyl configuration"). This means "Adamax" as sold may not refer to one single, consistent molecule across suppliers. Treat any specific structural or purity claim as unverified until confirmed against this lot's own Certificate of Analysis and independent mass spectrometry.

In laboratory settings, vendor literature proposes that Adamax, like Semax, may influence neurotrophin-related gene expression, though no independently published, peer-reviewed study on Adamax itself was identified during preparation of this page.

Disclaimer: Adamax is an unregulated research chemical with an unverified, vendor-inconsistent chemical identity  not an FDA-approved drug or dietary supplement. It is not intended to diagnose, treat, cure, or prevent any disease. This product is strictly for laboratory research purposes only.

ATTENTION: This product is strictly for LABORATORY AND RESEARCH PURPOSES ONLY. Not for human or veterinary use.

Mechanism of Action of Adamax

Adamax's Proposed Mechanism in Preclinical Models

Adamax is proposed by vendor literature to work similarly to Semax, a peptide studied for effects on BDNF and NGF gene expression and neurotrophin signaling. The added adamantane group is proposed to improve blood-brain-barrier penetration and metabolic stability relative to Semax.

Key limitations in the current evidence base:

• No independent verification: No independently published, peer-reviewed study on Adamax itself was identified. All mechanism claims trace back to inference from Semax's known pharmacology combined with vendor-authored technical material.
• Structural uncertainty undermines mechanistic claims: Because the exact structure of "Adamax" is disputed across vendors, any specific mechanistic claim about "the adamantane group" cannot be verified as applying to a single, consistent molecule.
• No detection or analytical method published: Unlike most compounds in this catalog, no validated analytical chemistry method (e.g., LC-MS/MS) for Adamax identity or purity confirmation was identified in the independent literature.

Chemical Properties of Adamax

Adamax

Property	Detail
PubChem CID	Not available
Molecular Formula	C50H69N11O11S  Not consistently reported across sources
Molecular Weight	Reported ~1,100–1,300 g/mol (vendor estimate; ~1,032.23 g/mol varies by source)
CAS Number	Not publicly documented; not independently verified Parent compound — Semax (H-Met-Glu-His-Phe-Pro-Gly-Pro-OH): MW 813.93 g/mol | Formula C37H51N9O10S | CAS 80714-61-0 (PubChem CID 122178). Adamax at ~1,032.23 g/mol is approximately 218 Da larger than Semax — reflecting N-terminal acetylation (+42 Da) and the C-terminal Ala-Gly-adamantylate extension (+~176 Da).
Sequence	Disputed reported variously as Ac-MEHFPGPAG-NH2 or with an adamantyl (Ad) substitution; not confirmed
Purity	Verify per Certificate of Analysis (batch-specific; no independent reference standard exists)
Physical Form	Lyophilized powder
Storage	-20°C, protected from light and moisture
Classification	Unregulated research chemical; not FDA-approved; not evaluated for safety or identity by any recognized authority

Research Applications of Adamax

1. Comparative Semax-Analogue Research Adamax is marketed for research comparing modified Semax derivatives against the parent compound, though this comparison has not been independently validated.
2. Blood-Brain-Barrier Penetration Modeling Vendor literature proposes Adamax as a tool for studying adamantane-mediated lipophilicity effects on peptide blood-brain-barrier penetration, though this claim has not been independently confirmed.
3. Identity and Purity Verification Method Development Because no validated public analytical method exists for Adamax, it may be relevant to researchers developing novel identity-confirmation and purity-testing methods for structurally ambiguous vendor peptides.

Risk and Handling Precautions

Risk Tier: HIGH (Identity Uncertainty)

This rating reflects the absence of a verified chemical identity, CAS number, or PubChem reference for this compound, meaning purity and identity claims rely entirely on the individual vendor's own testing without an independent reference standard. This is a materially higher-uncertainty risk profile than any other compound in this catalog, independent of the compound's biological activity. Researchers must observe the following precautions at all times. International regulatory note: Adamax has been identified in border seizures in New Zealand (2025) and is under review by NZ Medsafe for potential reclassification as a prescription medicine. Researchers outside the USA should confirm local regulatory status before ordering. 

Handling Precautions: Adamax should be handled by trained laboratory personnel only. Use appropriate personal protective equipment (PPE) at all times, including gloves and eye protection. Avoid direct skin contact, inhalation, or accidental exposure during laboratory handling.

Exposure Risks: No human or animal toxicity data exists for this compound under any of its disputed structural definitions. The absence of a reference standard means exposure risk cannot be meaningfully compared against known compounds.

Storage: Store at -20°C in a dry, dark environment protected from light, heat, and moisture. Check the batch Certificate of Analysis for lot-specific guidance. Do not use it if the seal has been compromised.

Toxicity and Data Limitations: No independently published toxicity, pharmacokinetic, or identity-confirmation data exist for Adamax under any of its reported structural definitions. Independent mass spectrometry verification of identity and purity is strongly recommended before any experimental use.

Why Choose BehemothLabz for Adamax?

BehemothLabz supplies Adamax for laboratory research purposes, with a Certificate of Analysis reflecting this specific batch's own third-party testing. Given the lack of a public reference standard for this compound, BehemothLabz recommends researchers independently verify identity and purity via their own analytical methods before relying on any vendor's specifications, including this one.

The compound is USA-made. It is available strictly to qualified researchers for use in controlled laboratory environments.

BehemothLabz Disclaimer

ATTENTION: All BehemothLabz products are strictly for LABORATORY AND RESEARCH PURPOSES ONLY. They are not to be used for any human or veterinary purposes.

Please make sure you go through the Terms and Conditions and familiarize yourself with them, as it is important. Kindly research the scientific uses of this product before making any purchases. Make note that the packaging and labels of the product may differ from those shown on the website.

Buying the product means you agree to our Terms and Conditions. You can contact our customer service team at support@behemothlabz.com if you are not fully satisfied with the product.

Adamax Research FAQs

Is Adamax a real, independently verified compound? 

Not in the way most research peptides are. There's no public PubChem entry or registered CAS number for it, and different vendors describe its structure differently. It's best understood as a marketed Semax-derivative concept rather than a single, well-characterized molecule. Acetyl Semax Amidate (MW ~856 Da) carries N-terminal acetylation and C-terminal amidation of the 7-residue Semax backbone. Adamax adds a C-terminal Ala-Gly-adamantylate extension (9 residues total, MW ~1,032 Da), further increasing lipophilicity and proposed CNS penetration beyond the amidate form. 

Is Adamax banned by WADA? 

It does not appear by name on the World Anti-Doping Agency's Prohibited List, checkable at wada-ama.org/en/prohibited-list. However, because its exact identity is unverified, this absence cannot be treated as a definitive clearance the way it can for a well-characterized compound.

Is Adamax FDA-approved? 

No. It has no FDA approval, and because its chemical identity isn't standardized across vendors, it also isn't the kind of compound that could currently be evaluated by the FDA in any consistent way.

Can I verify the chemical identity of Adamax independently? 

Not easily. Unlike other compounds in this catalog, there is no PubChem CID or CAS number to check it against. Independent mass spectrometry on the specific batch is the only reliable way to confirm what you've actually received.

Should I be concerned about buying something without a confirmed chemical identity? 

Yes, that's a legitimate concern. Without a public reference standard, you're relying entirely on the seller's own testing. Independent verification is strongly recommended before any research use.

How should Adamax be stored? 

Store at -20°C in a dry, dark environment protected from light, heat, and moisture. Check the batch Certificate of Analysis for lot-specific guidance. Do not use it if the seal has been compromised.

References

1. National Center for Biotechnology Information (NCBI). PubChem Compound Database. National Institutes of Health. Available at: https://pubchem.ncbi.nlm.nih.gov (searched; no verified Adamax entry found)
2. World Anti-Doping Agency. The 2026 Prohibited List International Standard (Adamax does not appear by name). Available at: https://www.wada-ama.org/en/prohibited-list

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