Humanin

Buy Humanin Peptide Online

Humanin is a naturally occurring mitochondrial-derived peptide that has attracted attention for research into cellular protection, mitochondrial function, neuroprotection, and healthy aging.

Product Information

Humanin is a 24-amino-acid peptide encoded by mitochondrial DNA. It was initially identified through research into neuronal survival and has since been investigated in models involving mitochondrial dysfunction, metabolic disease and cellular stress.

How It Works

Humanin interacts with several cellular signaling pathways involved in survival and apoptosis. Research has linked it with pathways involving BAX, JNK, STAT3 and IGF-related signaling, providing a potential explanation for its cytoprotective effects.

Potential Benefits

1. Cellular Protection

Humanin has demonstrated cytoprotective effects in a variety of experimental models. Researchers have studied its ability to help cells withstand oxidative and other forms of cellular stress.

2. Mitochondrial Research

Because Humanin originates from mitochondrial DNA, it is directly relevant to mitochondrial biology. Studies have investigated its role in maintaining cellular function during metabolic and oxidative stress.

3. Neuroprotection

Humanin has attracted substantial attention in neuroscience research. Experimental studies have examined its ability to protect neurons from apoptosis and other forms of cellular injury.

4. Healthy-Aging Research

Humanin levels and activity have been associated with aging biology. Animal studies have also investigated Humanin analogues in relation to metabolic healthspan and age-related changes.

Dosage

There is no established clinical dosage for Humanin. Experimental studies use different concentrations, administration methods, and research models.

Side Effects

A comprehensive human safety profile has not been established. Potential effects remain formulation- and route-dependent.

References

1. Xiao J, Kim SJ, Cohen P, Yen K. Humanin: Functional Interfaces with IGF-I. Growth Hormone & IGF Research. 2016. PMID: 27082450. PubMed
2. Nowak B, et al. Humanin and its derivatives as peptides with potential antiapoptotic and confirmed neuroprotective activities. Acta Biochimica Polonica. 2011. PMID: 22010475. PubMed
3. Hazafa A, et al. Humanin: A mitochondrial-derived peptide in the treatment of apoptosis-related diseases. Life Sciences. 2021;264:118679. PMID: 33130077. PubMed

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