MIF-1

Product Details: MIF-1 (Peptide)

MIF-1 (Melanocyte-Inhibiting Factor-1) is also known as Melanostatin. MIF-1 is a synthetic tripeptide. It is composed of the amino acid sequence Pro-Leu-Gly-NH₂. It belongs to a group of endogenous neuropeptides. It is investigated in biochemical and neurochemical research models.

MIF-1 is structurally related to peptides involved in neuropeptide signaling. It has been examined in laboratory studies focused on:

• peptide transport

• receptor interaction, and

• intracellular signaling mechanisms

Research on MIF-1 frequently examines its interactions with multiple molecular pathways in experimental systems.

The compound is supplied strictly as a research material intended for controlled laboratory investigation.

Properties of MIF-1 (Peptide):

• Molecular Formula: C₁₅H₂₅F₃N₄O₅
  
• Molecular Weight: 284.35 g/mol
  
• CAS Number: 478336-92-4
  
• PubChem CID: Not Available
  
• Synonyms: MIF-1; Melanostatin; Pro-Leu-Gly-NH₂; Melanocyte-Inhibiting Factor-1
  
• Peptide Class: Synthetic tripeptide
  
• IUPAC Name: Pro-Leu-Gly-NH₂

Mechanism of Action

Neuropeptide Signaling Interaction

MIF-1 has been investigated in laboratory experiments for its interaction with multiple intracellular signaling pathways. These are the ones associated with peptide-mediated molecular communication. Experimental data indicate that the peptide may influence cellular signaling markers such as pERK and STAT3 phosphorylation pathways in neuronal cell models.

Receptor Binding Investigations

Studies examining MIF-1 and related peptides have reported that these compounds may exhibit distinct receptor-binding characteristics compared with structurally similar peptides found in neural tissues. Analytical work on related peptides in the MIF-1 family has identified unique receptor interaction profiles in brain tissue preparations.

Peptide Transport and Molecular Stability

Due to its small peptide structure, MIF-1 is commonly examined in research investigating peptide transport mechanisms and molecular stability within biological systems. Its simple tripeptide composition allows researchers to analyze structure–function relationships in short peptide signaling molecules.

Research Applications

In controlled laboratory environments, MIF-1 may be utilized for investigations involving:

• peptide signaling pathway analysis
  
• receptor-binding characterization studies
  
• neuropeptide transport and distribution research
  
• structure–activity relationship studies involving short peptides
  
• analytical characterization of tripeptide signaling molecules

All applications are restricted strictly to analytical and experimental research environments.

Why Choose BehemothLabz to Buy MIF-1 (Peptide)

BehemothLabz is committed to providing high-purity research peptides manufactured under strict quality control standards. Each batch of MIF-1 undergoes independent third-party testing to verify identity, purity, and consistency. With a focus on scientific reliability and transparency, BehemothLabz supports researchers with dependable compounds suitable for advanced laboratory and preclinical investigations.

Disclaimer: This information is for educational purposes. We do not allow the human consumption of our products. All our products are sold for laboratory and research experiments.

ATTENTION: All BehemothLabz products are strictly for LABORATORY AND RESEARCH PURPOSES ONLY. They are not to be used for any human or veterinary purposes.

References:

1. Khan, R. S., Yu, C., Kastin, A. J., et al. Brain activation by peptide Pro-Leu-Gly-NH₂ (MIF-1). International Journal of Peptides. PubMed: https://pubmed.ncbi.nlm.nih.gov/20721355/
2. Hackler, L., Kastin, A. J., & Zadina, J. E. Isolation of a novel peptide with a unique binding profile from human brain cortex: Tyr-K-MIF-1. Peptides. PubMed: https://pubmed.ncbi.nlm.nih.gov/7991457/

 

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