PQQ Disodium Powder

Buy PQQ Disodium Powder Online

PQQ Disodium, or pyrroloquinoline quinone disodium salt, is a water-soluble form of PQQ widely studied for its antioxidant, mitochondrial, and cognitive properties. Human trials have investigated daily supplementation for cognitive function and metabolic markers.

Product Information

PQQ Disodium has been evaluated in randomized controlled trials using approximately 20-21.5 mg/day for 12 weeks. Studies have reported improvements in selected cognitive measures, while mechanistic research continues to investigate PQQ's redox and mitochondrial effects.

How It Works

PQQ is a redox-active quinone that can participate in cellular electron-transfer processes. Research has associated it with antioxidant effects and signaling pathways involved in mitochondrial function and cellular adaptation.

POTENTIAL BENEFITS

1. Supports Cognitive Function

Human randomized trials have reported improvements in selected measures of memory, attention, reaction time, and cognitive flexibility following PQQ supplementation.

2. Mitochondrial Research

PQQ has attracted significant attention because of its relationship with mitochondrial signaling and biogenesis pathways. This makes it particularly relevant to research into cellular energy production and healthy aging.

3. Antioxidant Activity

PQQ's redox chemistry allows it to participate in antioxidant-related cellular processes. Human research has also reported reductions in selected oxidative-stress markers following supplementation.

4. Healthy Aging Research

Because mitochondrial function, oxidative stress, and cognitive performance all change with age, PQQ has become an increasingly studied compound in healthy-aging research.

Dosage

Human clinical trials have commonly used 20 mg/day of PQQ disodium, while another 12-week randomized trial used 21.5 mg/day. These doses were administered under controlled study conditions and should not be interpreted as a universal requirement.

Side Effects

PQQ has generally been well tolerated in short-term human supplementation studies. Possible adverse effects may include gastrointestinal discomfort, headache, or other mild symptoms. Long-term high-dose safety remains less established than short-term supplementation.

References

1. Tamakoshi M, et al. Pyrroloquinoline quinone disodium salt improves brain function in both younger and older adults. Food Funct. 2023;14(5):2496-2501. PMID: 36807425. PubMed
2. Shiojima Y, et al. Effect of Dietary Pyrroloquinoline Quinone Disodium Salt on Cognitive Function in Healthy Volunteers. J Am Coll Nutr. 2022;41(8):796-809. PMID: 34415830. PubMed
3. Ikemoto K, Ishak NSM, Akagawa M. The effects of pyrroloquinoline quinone disodium salt on brain function and physiological processes. J Med Invest. 2024;71(1.2):23-28. PMID: 38735721. PubMed
4. Shiojima Y, et al. Safety assessment of a novel, dietary pyrroloquinoline quinone disodium salt. J Toxicol Environ Health A. 2022;85(17-18):662-677. PMID: 35546737. PubMed

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