Amentoflavone (20% Extract) Powder

Buy Amentoflavone (20% Extract) Powder Online

Amentoflavone is a naturally occurring biflavonoid found in several medicinal plants, including Selaginella species. A standardized 20% extract provides a concentrated source of Amentoflavone for nutritional and research applications.

Product Information

Amentoflavone has been extensively investigated for antioxidant, anti-inflammatory, metabolic, neurological, and cellular effects. Despite its broad preclinical profile, poor water solubility and limited bioavailability have restricted its development as a conventional therapeutic drug.

How It Works

Amentoflavone influences multiple molecular pathways, including inflammatory signaling, oxidative-stress pathways, and cellular kinase systems. It is therefore considered a multi-target flavonoid rather than a compound acting through a single receptor.

POTENTIAL BENEFITS

1. Antioxidant Activity

Amentoflavone has demonstrated significant antioxidant activity in laboratory research, making it relevant to studies involving oxidative stress and cellular protection.

2. Anti-Inflammatory Research

Research has identified effects on inflammatory pathways, including NF-kB and related signaling networks. This broad activity has contributed to substantial interest in Amentoflavone research.

3. Neuroprotective Research

Amentoflavone has been investigated in neurological models involving oxidative stress, inflammation, neuronal signaling, and cellular survival, creating a broad neuroprotective research profile.

4. Metabolic Research

Experimental research has examined Amentoflavone in relation to glucose and lipid metabolism, including pathways relevant to metabolic dysfunction and healthy aging.

Dosage

There is no established human therapeutic dosage for Amentoflavone. A 20% extract is formulation-specific, so the actual Amentoflavone content depends on the total extract quantity. Human dosing should not be inferred from animal studies.

Side Effects

Human safety data are limited. Amentoflavone also has demonstrated the ability to inhibit several drug-metabolizing enzymes in laboratory studies, creating potential drug-interaction concerns.

References

1. Yu S, Yan H, Zhang L, et al. A Review on the Phytochemistry, Pharmacology, and Pharmacokinetics of Amentoflavone, a Naturally-Occurring Biflavonoid. Molecules. 2017;22(2):299. PMID: 28212342. PubMed
2. Zhang X, et al. Insights Into Amentoflavone: A Natural Multifunctional Biflavonoid. Front Pharmacol. 2022. PMID: 35002708. PubMed
3. Wang Y, et al. Amentoflavone for treating cardiocerebrovascular diseases and neurological disorders. Front Pharmacol. 2024. PMID: 39624841. PubMed

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