Protirelin (TRH Thyrotropin)

Protirelin (TRH Thyrotropin) (Peptide) – Product Details

Protirelin (TRH Thyrotropin), is a synthetic tripeptide hormone. It is mostly found in the hypothalamus of different research subjects. Various studies have shown that it has the potential to influence the endocrine system, particularly the thyroid gland and the pituitary gland. TRH thyrotropin may influence the production of thyroid hormones (T3 and T4) from the thyroid gland of test subjects. 

Additionally, it may also be used to treat a variety of neurological disorders, including intractable epilepsy in research participants.

How Does Protirelin Work?

According to preclinical studies, Protirelin works by influencing the two most important glands: the thyroid gland and the pituitary gland. Stimulating these glands may enhance the secretion of the Thyroid Stimulating Hormone (TSH). TSH, in return, signals the thyroid gland of subjects to increase the production of thyroid hormones. The released thyroid hormones then perform various roles in the subject’s body. 

Properties of Protirelin 

• Molecular Formula: C16H22N6O4
• Synonyms: Thyroliberin, TRH, Thyrotropin-releasing Hormone
• IUPAC Name: (2S)-N-[(2S)-1-[(2S)-2-carbamoylpyrrolidin-1-yl]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxo pyrrolidine-2-carboxamide
• Molecular Weight: 362.38 g/mol
• CAS Number: 24305-27-9
• PubChem CID: 638678

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