Exemestane is a medication used to treat breast cancer. It is a member of the class of antiestrogens known as aromatase inhibitors (AIs). Some breast cancers require estrogen to grow. Those cancers have estrogen receptors (ERs) and are called ER-positive. They may also be called estrogen-responsive, hormonally responsive, or hormone-receptor-positive. Aromatase is an enzyme that synthesizes estrogen. Aromatase inhibitors block the synthesis of estrogen. This lowers the estrogen level and slows the growth of cancers. Exemestane may also be used to lower estrogen levels in people without cancer.
Selective Androgen Receptor Modulators (SARMs) – therapeutic compounds with similar properties to anabolic agents, but with reduced androgenic properties. They have advantage of androgen-receptor specificity, tissue selectivity, and lack of steroid-related side effects.
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