VIP (Vasoactive Intestinal Peptide)

Buy VIP (Vasoactive Intestinal Peptide) Online

Vasoactive intestinal peptide (VIP) is a naturally occurring neuropeptide with broad activity throughout the nervous, gastrointestinal, vascular, and immune systems. It has been studied extensively because of its ability to influence smooth muscle, blood vessels, secretion, and inflammatory signaling.

Product Information

VIP peptide is a 28-amino-acid peptide produced in the central and peripheral nervous systems and several other tissues. It acts through G-protein-coupled VPAC receptors and plays an important role in regulating vascular tone, intestinal function, neurotransmission, and immune responses.

How It Works

VIP activates VPAC1 and VPAC2 receptors, increasing intracellular cyclic AMP. This signaling can relax smooth muscle, influence secretion, alter blood flow, and regulate immune-cell activity.

POTENTIAL BENEFITS

1. Vascular Research

VIP is a potent vasodilatory neuropeptide, making it useful for studying vascular tone, blood-flow regulation, and smooth-muscle relaxation.

2. Gastrointestinal Research

VIP plays a major role in gastrointestinal neural signaling and can influence intestinal smooth muscle and secretory activity.

3. Respiratory Research

VIP has been investigated for effects on pulmonary signaling, surfactant biology, inflammation, and airway-related pathways.

4. Immune-Modulation Research

VIP can influence cytokine production and immune-cell activity, making it an important target for research into neuroimmune communication.

Dosage

VIP has been administered in controlled human clinical studies under specific medical protocols. For example, clinical investigations of synthetic VIP (aviptadil) have used intravenous administration under hospital research conditions. These protocols are indication-specific and should not be treated as a general dosing recommendation for research-grade VIP.

Side Effects

VIP can produce vasodilation and gastrointestinal effects, including changes in blood pressure, flushing, abdominal effects, and heart-rate changes. The risk profile depends on dose, route, and underlying cardiovascular status.

References

1. PubMed — VIP / Aviptadil randomized clinical trial
2. PubMed — Vasoactive intestinal peptide physiology

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