ACE 031 (Peptide) – Product Details

ACE-031 is a cutting-edge research compound designed for scientific investigation into its potential applications in the field of muscle-related research.

• CAS Number: 616204-22-9
• Molar Mass: 1311.45 g/mol
• Chemical Formula: C33H57N11O9
• IUPAC Name: UNII-U8DGS69FVC, U8DGS69FVC, 1621169-52-5, CHEMBL3410227, Myostatin inhibitory peptide 7, BDBM50071379, ACE-031, Myostatin inhibitory peptide 7 Ala-Trp-Arg-Gln-Asn-Thr-Arg-Tyr-Ser-Arg-Ile-Glu-Ala-Ile-Lys-Ile-Gln-Ile-Leu-Ser-Kys-Leu-Arg-Leu-NH2
• Also known by various synonyms including Myostatin inhibitory peptide 7 and UNII-U8DGS69FVC.

What is ACE 031?

ACE-031, a potent myostatin inhibitor, demonstrates a robust affinity for binding to myostatin (GDF-8). By doing so, it effectively prevents myostatin from engaging with its natural ACVR2B receptor, which typically suppresses muscle growth by transmitting growth-limiting signals.

This unique mechanism of action positions ACE-031 as a promising candidate for fostering the development and preservation of muscles, leading to substantial skeletal muscle hypertrophy. This distinctive attribute suggests that ACE-031 holds significant potential in the realm of neuromuscular disease research, showcasing a capacity to address symptoms associated with such conditions.

Research Potential of ACE 031

ACE 031 and Muscle Protection

Research investigating ACE 031’s impact on muscle protection during menopause was conducted in a limited clinical setting. The focus was on assessing its potential to aid in the preservation of muscle mass in postmenopausal, healthy women, recognizing the crucial role of muscle maintenance in ensuring long-term bone health. In a brief placebo-controlled trial, a single dose of ACE 031 demonstrated a significant increase in lean body mass and thigh muscle volume.

Remarkably, the study unveiled an unexpected secondary outcome. Participants receiving ACE 031 exhibited improvements in serum indicators related to both fat and bone metabolism. This suggests that ACE 031 may not only restrict fat storage but also promote bone development, expanding its potential benefits beyond muscle growth. [R]

ACE 031 and Facilitating Muscle Repair

Duchenne muscular dystrophy, an x-linked recessive disease, leads to severe muscle atrophy, often resulting in elevated fat content and diminished protein content in a child’s muscles by the age of 12. The fragility of muscle cells in this condition, attributed to dysfunctional dystrophin protein, makes them prone to injury. While myostatin exacerbates the disease’s impact by impeding the growth of other cells, ACE 031 shows promise in mitigating muscle deterioration by addressing this secondary effect, especially when conventional gene therapy for dystrophin dysfunction has faced challenges.

In a recent clinical trial, ACE 031 was administered subcutaneously at intervals of two to four weeks. This intervention exhibited a tendency to maintain the 6-minute walk test, indicating the peptide’s potential in preserving muscular function. Moreover, there was an observed trend toward increased bone mineral density, reduced fat mass, and enhanced lean body mass. [R]

ACE 031 and Enhanced Bone Density

In a seven-week study, ACE 031 was administered weekly to mice modeling Duchenne muscular dystrophy. At the study’s conclusion, the mice treated with ACE 031 exhibited significantly elevated muscle and bone mineral density compared to their initial levels.

This increase in bone density was attributed to a reduction in osteoclasts, the cells responsible for breaking down bone. Strength tests revealed improved biomechanics in the bones, evident in both increased maximum force endurance and bone stiffness, indicating purposeful additional mass. This study presents empirical evidence, showcasing a remarkable up to 30% enhancement in bone mass in treated mice, suggesting ACE 031’s potential exploration for osteoporosis treatment. [R]

ACE 031 and Promotion of Muscle Cell Growth

Research in mice suggests that optimal skeletal muscle development can be achieved only through myostatin inhibition, with ACE 031 emerging as a potent candidate. Moreover, it seems that employing various pathways for myostatin blockage may prove to be the most effective approach.

While these findings are in the early stages, they suggest that a comprehensive strategy may be essential for the most robust muscle protection in situations leading to muscle wasting. This approach involves treatments that not only stimulate muscle growth (such as growth hormone and IGF-1) but also mitigate muscle wasting, where ACE 031 could play a crucial role. [R]

How Does ACE 031 Work?

ACE 031 functions as a myostatin inhibitor, exerting its effects by binding with high affinity to myostatin (GDF-8). This binding prevents myostatin from activating its natural ACVR2B receptor, responsible for suppressing muscle growth by delivering a growth-limiting signal. By inhibiting myostatin’s action, ACE 031 has the potential to support the development and maintenance of muscles, contributing to maximal skeletal muscle hypertrophy. This unique property positions ACE 031 as a promising avenue for research, particularly in the context of neuromuscular diseases, where it could potentially assist in mitigating symptoms related to muscle atrophy.

Frequently Asked Questions

What is ACE 031 used for in research?

ACE 031 is primarily used in research as a myostatin inhibitor, aiming to investigate its potential to promote muscle growth and prevent muscle atrophy.

How does ACE 031 differ from other myostatin inhibitors?

ACE 031 works by binding to myostatin, preventing its natural receptor activation. This unique mechanism sets it apart from other myostatin inhibitors, offering researchers a specific avenue for studying muscle-related effects.

Summary

In research studies, ACE 031, a potent myostatin inhibitor, has exhibited promising outcomes related to muscle health and skeletal muscle growth. Clinical trials exploring ACE 031’s effects on conditions such as Duchenne muscular dystrophy have shown statistically significant increases in skeletal muscle mass, thigh muscle volume, and muscle volume. These outcomes suggest a potential avenue for improving muscle mass and skeletal muscle growth in situations involving muscle wasting. Moreover, ACE 031 has demonstrated statistically significant changes in total body lean mass, highlighting its impact on overall muscle composition. Researchers have also noted its potential influence on fat metabolism and muscle nerve health. While findings indicate positive trends, careful consideration of adverse events and adherence to ethical guidelines in clinical trials remains crucial for a comprehensive understanding of ACE 031’s effects on muscle-related parameters and myostatin signaling pathways.

Why Buy ACE 031 From BehemothLabz

BehemothLabz has established itself as a reliable and reputable source for research compounds since 2014. We take pride in offering the highest-quality products that are backed by independent, third-party-issued Certificates of Analysis for identification, purity, and concentration.

Our commitment to quality extends to every aspect of our business, from same-day processing to free shipping on all orders over $100 and our satisfaction guarantee.

At BehemothLabz, we understand the importance of having access to the best compounds for research purposes. Our team is dedicated to providing exceptional customer service and ensuring that our customers have access to the compounds they need to conduct groundbreaking research.

We also offer international shipping to our customers around the world. Our team is committed to ensuring that your order arrives after research is needed to fully understand its mechanisms of action and potential applications in the treatment of various conditions.

It is critical to purchase ACE 031 from reputable vendors such as Behemoth Labz to ensure purity and quality.

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