4 Andro, also known as 4-DHEA, is a prohormone. It is directly converted by the body into testosterone and doesn’t aromatize into estrogen. Unlike some other prohormones, 4 Andro isn’t converted to dihydrotestosterone (DHT) or any of its derivatives.
Research has shown that the administration of 4 Andro causes a significant increase in free and total serum testosterone concentrations. DHEA, the main active ingredient of 4 Andro, has been found to increase muscle strength and IGF-1 levels in human subjects.
Behemoth Labz sells 4 Andro for laboratory research purposes only.
CAS Number is stated as 1156-92-9
Molar Mass is 290.447 g·mol−1
It has a Chemical Formula of C19H30O2
IUPAC Name is (3S,8R,9S,10R,13S,14S,17S)-10,13-dimethyl-2,3,6,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,17-diol
Also known by Synonyms as Androst-4-ene-3β,17β-diol
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What is 4-Andro?
4 Andro, also known as 4-DHEA or 4-Androstenediol, belongs to a class of chemicals known as prohormones. Prohormones are chemicals converted by the body into anabolic hormones that, in turn, stimulate protein synthesis and enhance muscle growth. [R]
4-Andro is a metabolite of DHEA, a natural hormone the body uses to make male and female sex hormones. 4 Andro itself is treated by the body as a precursor of testosterone, meaning the body uses this novel prohormone to produce the male sex hormone. [R][R]
4 Andro’s positive effects on testosterone led to this research chemical increasing skeletal muscle growth in animal studies. More importantly, despite the elevation in testosterone levels and increase in muscle growth, 4 Andro didn’t have adverse effects on sex organs. [R]
How does 4-Andro Work?
The body has the potential to convert 4 Andro to other hormones, including testosterone (male sex hormone) and estrogen (female sex hormone). The enzyme 3 β-hydroxysteroid dehydrogenase is reportedly responsible for converting 4 Andro to testosterone. [R]
4-Andro is much closer to testosterone structurally than it is to estrogen. This explains why it’s strongly androgenic and weakly estrogenic. As much as 15.76% of 4 Andro is converted to testosterone, a conversion rate that is three times that of 4-Androstenedione. [R]
Various studies have been conducted on 4 Andro as well as on one of its main active ingredients. These studies have shown that 4 Andro could stimulate muscle growth, increase IGF-1 levels, boost muscular strength, and raise serum total testosterone levels.
The information given in this guide is for educational purposes only. Speak to your healthcare professional to know more about Hi-Tech Pharmaceuticals Androdiol 4 Andro.
4-Andro and Muscle Growth
According to an animal study, 4 Andro and other selected steroid precursors stimulated normal muscle growth in castrated guinea pigs over a 10-week period. Significantly, the growth of prostate and seminal vesicles in the 4 Andro group should have little or no treatment effect. [R]
Furthermore, the total skeletal muscle growth of the 4 Andro treatment group was significantly more than the castrated empty group. Researchers conducting the study noted that this effect was because 4 Andro significantly elevated circulating testosterone levels in treated animals.
Overall, 4-Andro was particularly effective in stimulating above-normal muscle growth, the volume of individual muscle compartments, and total skeletal muscle in treated groups. Equally importantly, 4 Andro had no detrimental effect on the growth of sexual organs and tissues.
4-Andro and Testosterone
In a 12-week clinical study involving men (ages 35 to 65), both untrained and resistance training trained men were administered 4 Androstenediol. Results from the study show that there was an acute rise in total- and free-testosterone levels in younger men. [R]
Another study investigated the effects of a high dose of 4 Andro (500mg thrice daily) on testosterone in nine healthy hypogonadal men. Once again, it was found that 4 Andro treatment significantly increased total and free testosterone levels. [R]
Research has demonstrated that the conversion rate of 4 Androstenediol to testosterone is about 15.76%, about triple that of 4-Androstenedione, a naturally occurring DHEA isomer. That is because 4 Andro utilizes a different enzymatic pathway to convert to testosterone. [R]
4-Andro and IGF-1
Dehydroepiandrosterone (DHEA) is the main active ingredient of 4 Andro. In a clinical study involving age-advanced men and women, six-month treatment with a 100mg daily dose of DHEA resulted in a significant elevation in insulin-like growth factor 1 (IGF-1) levels in both. [R]
The same group of researchers then explored the effects of a bigger DHEA dose (100 mg). This study involved both men and women and continued for a longer duration (6 months). Still, 4 Andro was found to stimulate an increase in serum IGF-1 levels in both genders. [R]
4-Andro and Body Weight
Various pre-clinical studies have shown that DHEA administration reduces body weight via a reduction in body fat. To explore whether these effects were observed in humans, a double-blind placebo-controlled study investigated the effects of DHEA treatment on abdominal fat in elderly humans. [R]
Results from the study show that 6-months of DHEA treatment resulted in significant decreases in abdominal visceral fat. These decreases were of similar magnitude in both genders, with women experiencing a higher decrease in visceral fat relative to initial values than men.
In addition to decreasing abdominal visceral fat, DHEA therapy also significantly reduced abdominal visceral fat. Furthermore, while women experienced a higher reduction in abdominal visceral fat, the average decrease in abdominal subcutaneous fat was the same (6%) in men and women.
4-Andro and Muscle Strength
The above study also measured the effects of long-term DHEA treatment on muscular strength. In contrast to the elevation in IGF-1 levels, which was observed in both males and females, the increase in muscle strength was observed only in men.
An increase in muscle strength was observed along knee muscles and lumbar back muscles. The former was of particular interest to researchers as knee weakness leads to morbidity and falls in the elderly. However, the mechanism by which DHEA increased muscle strength remained unknown.
4-Andro and Depression
A meta-analysis of studies was conducted to investigate whether DHEA was more effective in the treatment of depressive symptoms than placebo. It was found that DHEA may be a more effective alternative to the drugs used in the treatment of depression. [R]
In another study, the effects of DHEA administration on six middle-aged and elderly patients with major depression and low basal plasma DHEA levels were observed. Results from the study suggest that DHEA may have anti-depressant and pro-memory effects. [R]
Frequently Asked Questions
What are the differences between 1-Andro and 4-Andro?
The major difference between 1 Andro and 4 Andro is that the former isn’t converted to estrogen by the body, whereas 4 Andro does. Even though the conversion rate of 4 Androstenediol to testosterone is about 15.76%, almost triple that of 4-androstenedione.
Does 4-Andro increase testosterone?
In a 12-week clinical study involving men (ages 35 to 65), both untrained and resistance training trained men were administered 4 Androstenediol. Results from the study show that there was an acute rise in total- and free testosterone in younger men. [R]
What does 4-Andro convert to?
Health experts state that the body converts 4 Andro to other chemicals called hormones. Some of these hormones include testosterone (male sex hormone) and estrogen (female sex hormone). [R]
Where to Buy 4-Andro for Sale?
Behemoth Labz is the best place to buy 4 Andro online.
We have been around since 2014, supplying the highest-quality research compounds money can buy. All of our products come with a 100% satisfaction guarantee, free and fast shipping, and a money-back guarantee. We also carry SARMs and peptides.
4 Andro (4 Androstenediol) is a prohormone that the body converts to testosterone. Research has shown that 4 Andro doesn’t only raise total and free serum testosterone levels.
This potential testosterone booster also increased lean muscle mass and helped with muscle recovery and lean tissue growth without any exercise program. That too without detrimentally affecting sexual organs or causing any other reproductive harm.
Please make sure you go through the Terms and Conditions, and please familiarize yourself with it as it is important. Please research the scientific uses of this product before making any purchases. Make note that the packaging and labels of the product may differ from those shown on the website.
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