ACTH 1-34 (Peptide) – Product Details

ACTH 1-34, or Adrenocorticotropic Hormone 1-34, is a peptide sequence consisting of the first 34 amino acids of the naturally occurring ACTH hormone. This synthetic version is often utilized in research settings for its potential role in stimulating the adrenal glands to produce corticosteroids, which are vital for various physiological processes. Researchers investigate its impact on adrenal function, cortisol release, and related pathways.

• CAS Number: 12279-41-3
• Molar Mass: 4541 g/mol
• Chemical Formula: C207H308N56O58S
• IUPAC Name: H-DL-Ser-DL-Tyr-DL-Ser-DL-Met-DL-Glu-DL-His-DL-Phe-DL-Arg-DL-Trp-Gly-DL-Lys-DL-Pro-DL-Val-Gly-DL-Lys-DL-Lys-DL-Arg-DL-Arg-DL-Pro-DL-Val-DL-Lys-DL-Val-DL-Tyr-DL-Pro-DL-Asn-Gly-DL-Ala-DL-Glu-DL-Asp-DL-Glu-DL-Ser-DL-Ala-DL-Glu-DL-Ala-DL-Phe-DL-Pro-DL-Leu-DL-Glu-DL-Phe-OH
• Synonyms: ACTH 1-34, Adrenocorticotropic Hormone 1-34

What is ACTH 1-34?

As mentioned above, ACTH 1-39, scientifically known as adrenocorticotropic hormone ACTH 1-39, stands as a unique research entity distinguished by its exceptional composition and attributes. Originating from the broader adrenocorticotropic hormone (ACTH), this specific fragment constitutes a condensed iteration that preserves essential operational components.

Through assiduous investigation and empirical studies, researchers have isolated ACTH 1-39, unveiling its capacity to reveal novel pathways in scientific comprehension. ACTH 1-39 serves as a catalyst for cortisol generation, muscle cell activity, metabolic processes, and modulation of the HPA stress axis. The HPA (hypothalamic-pituitary-adrenal) stress axis, constituting a neuroendocrine framework, governs the body’s stress response.

This intricate system engages the hypothalamus, pituitary, and adrenal glands. When confronted with stress, this axis deploys hormones such as CRH and ACTH, which, in turn, stimulate the production of cortisol. Cortisol, a pivotal player, exerts influence over the immune system, metabolism, and stress modulation. Dysregulation of the HPA axis can reverberate into health conditions. Comprehending this mechanism holds the potential to effectively manage stress-induced ailments.[R]

Potential Research Applications of ACTH 1-39

ACTH 1-39, a research compound derived from adrenocorticotropic hormone, has garnered significant attention due to its potential benefits across various scientific disciplines.

Neurological Potential

A pioneering study featured in the Journal of Neuroscience delved into the ramifications of ACTH 1-39 concerning neuronal adaptability. The findings unveiled that ACTH 1-39 fostered elevated synaptic plasticity and fortified neuronal robustness. These outcomes hint at its capacity for enhancing cognitive capabilities and offering safeguards for neurological well-being. (R)

Potential Effects on the Immune System

A study detailed in the Journal of Immunology explored ACTH 1-39’s capacity to influence immune responses. The investigation unveiled that the utilization of ACTH 1-39 markedly mitigated inflammation-associated harm and orchestrated the activation of immune cells. These discoveries underscore the compound’s promise as a potential therapeutic tool in managing immunological disorders, encompassing autoimmune ailments. (R)

Metabolic Regulation

An extensive examination featured in the journal Diabetes delved into ACTH 1-39’s influence on the equilibrium of glucose and the sensitivity to insulin. The research team showcased that the application of ACTH 1-39 led to advancements in glucose tolerance, heightened insulin sensitivity, and augmented functionality of pancreatic beta cells. These outcomes propose that ACTH 1-39 could potentially offer a prospect in shaping innovative treatments for metabolic irregularities, including type 2 diabetes. (R)

Potential to Counter Inflammation

In an animal study featured in the Journal of Inflammation, scientists explored the potential of ACTH 1-39 as an anti-inflammatory agent. The outcomes indicated that ACTH 1-39 led to a substantial reduction in the generation of pro-inflammatory cytokines and mitigated tissue impairment within an experimental inflammation scenario. These revelations imply that this substance might hold significant promise in devising strategies aimed at countering inflammation. (R)

How Does ACTH 1-39 Work?

The mechanism of action of ACTH 1-39 lies in its interactions within the intricate network of the hypothalamic-pituitary-adrenal (HPA) axis, a vital component of the body’s stress response system. The HPA axis involves the hypothalamus, pituitary gland, and adrenal glands and plays a crucial role in regulating stress-induced reactions. When confronted with stress, the hypothalamus releases corticotropin-releasing hormone (CRH), which stimulates the pituitary gland to produce adrenocorticotropic hormone (ACTH). In turn, ACTH prompts the adrenal glands to release cortisol, a hormone pivotal for immune function, metabolism, and stress modulation.

Frequently Asked Questions

Is ACTH 1-39 involved in metabolic regulation?

Studies propose that ACTH 1-39 could advance glucose tolerance, heighten insulin sensitivity, and augment pancreatic beta cell functionality, offering potential in metabolic treatments.

Can ACTH 1-39 potentially counter inflammation?

Animal studies suggest that ACTH 1-39 may act as an anti-inflammatory agent by reducing pro-inflammatory cytokines and mitigating tissue damage in experimental inflammation scenarios.

Why Buy ACTH 1-39 From BehemothLabz

BehemothLabz has established itself as a reliable and reputable source for research compounds since 2014. We take pride in offering the highest-quality products that are backed by independent, third-party-issued Certificates of Analysis for identification, purity, and concentration.

Our commitment to quality extends to every aspect of our business, from same-day processing to free shipping on all orders over $100 and our satisfaction guarantee.

At BehemothLabz, we understand the importance of having access to the best compounds for research purposes. Our team is dedicated to providing exceptional customer service and ensuring that our customers have access to the compounds they need to conduct groundbreaking research.

We also offer international shipping to our customers around the world. Our team is committed to ensuring that your order arrives after research is needed to fully understand its mechanisms of action and potential applications in the treatment of various conditions.

It is critical to purchase ACTH 1-39 from reputable vendors such as Behemoth Labz to ensure purity and quality.

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Strength	5mg