What is Peptide Nasal Spray?
Peptides are a class of compounds that consist of small chains of amino acid molecules. They usually exist in parenteral, aqueous, transdermal, and intranasal delivery systems. When they are formulated into molecular forms inside an enclosed container, they are known as peptide nasal sprays.
As the name suggests, peptide nasal spray is administered via the intranasal route in research subjects. This dispensation through the nasal cavity enhances bioavailability relative to alternative peptide delivery modalities and thus produces more rapid pharmacodynamic responses.
Mechanism of Action of Peptide Nasal Spray
Peptide nasal spray is dispensed through the nasal cavity in research subjects. After dispersion, it may achieve systemic circulation via direct absorption and thus bypass first-pass gastrointestinal metabolism. This gastrointestinal bypass via mucosal uptake makes the peptide nasal spray achieve faster and more efficient systemic activity in research subjects. The bloodstream directly transports peptides from the nasal spray to target-specific physiological sites.
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