SS-31 (Elamipretide)

What is SS31 Elamipretide?

SS-31, also known as Elamipretide (ELAM) or Bendavia, is a novel class of tetrapeptide being investigated for its potential mitochondrial influence. SS-31 is an antioxidant that selectively binds to cells to target the mitochondria potentially resulting in improved physiological function. [R]

How SS31 Elamipretide works?

Elamipretide works by binding to cardiolipin in mitochondrial membranes. This causes an alteration in lipid packing and surface electrostatics. These modifications result in mitoprotective benefits in diseases including heart failure and dementia by stabilizing the membrane, lowering oxidative stress, and increasing ATP synthesis.[R].

Properties:

• Chemical Formula:  C32H49N9O5
• Synonym: Elamipretide / Bendavia / SS-31 peptide /Arg-Dmt-Lys-Phe-NH2
• IUPAC-Name: (2S)-6-amino-2-[[(2S)-2-[[(2R)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]-N-[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]hexanamide;trihydrochloride
• Molar Mass: 639.8 g/mol
• CAS Number: 736992-21-5
• PubChem CID: 11764719
• Shelf Life: 24 months

Potential Benefits SS31 Elamipretide

SS-31 has been subject to numerous fields of study. Below are some of the relevant findings:

SS31 Elamipretide Peptide and Treatment for Aging

Researchers investigated the mechanism behind SS-31’s potential to restore age-related functional impairments in the heart. The results from the study found that aging heart cells tend to have more oxidative damage, however following 8 weeks of treatment with Elamipretide, the damage was almost completely reversed. This suggests that SS-31 has the potential to reduce oxidative stress in aging cells and help to restore heart function [R].

SS31 Elamipretide Peptide on Oxidative Stress and Diabetes

In recent years, a lot of attention has been given to the potential impact of mitochondrial impairment in the pathogenesis of type 2 diabetes. As a result, treating mitochondrial dysfunction could be a way to ameliorate some of the long-term effects of diabetes such as oxidative damage to small vessels. In a study where humans were administered SS-31, a marked reduction in the production of reactive oxygen species was observed. This seems to suggest that SS-31 may have the potential to reduce the oxidative damage that usually accompanies mitochondrial dysfunction. This may slow down or possibly even stop the progression of microvascular disease in type 2 diabetes. [R]

SS31 Elamipretide Peptide on the Potential to Restore Muscle Strength

A key indicator of aging is mitochondrial dysfunction. This plays a massive role in the incidence of genetic diseases, heart failure, tissue damage from blood flow loss (reperfusion injury), kidney damage, and the decline of muscle mass and strength with age [R].

SS-31 as a mitochondria-targeting peptide, has the potential to make aging muscles more responsive to Adenosine diphosphate (ADP). ADP is converted to adenosine triphosphate (ATP) by the enzyme ATP synthase. This means SS-31 has the ability to boost ATP production. This has the potential ability to improve muscle repair, inflammatory response, and overall function. [R].

SS31 and Neurocognitive Disorders

Elamipretide is being studied for its potential to mitigate the negative effects of inflammation and oxidative stress on cognition.

SS31 was investigated in rodent models for the treatment of hippocampal-related memory and learning deficits caused by oxidative stress, and neuroinflammation lipopolysaccharide (LPS)-induced mitochondrial dysfunction. SS31 showed the potential to lower oxidative stress, inhibit mitochondrial damage, and control brain-derived neurotrophic factor (BDNF) signaling. This may contribute to restoring disrupted synaptic signaling protein and the augmentation of synaptic structural complexity. These findings suggest that Elamipretide may have therapeutic applications for the prevention and treatment of perioperative neurocognitive disorders (PND) by emphasizing mitochondrial health.

Why Choose BehemothLabz to Buy SS31 Elamipretide

Looking for a reliable, trustworthy, and top-quality source to buy SS-31 (Elamipretide) online? Behemothlabz has a stellar reputation for providing the best 3rd party tested peptides online.

We have been around since 2014, supplying the highest-quality research compounds money can buy. Our products come with a 100% satisfaction guarantee, free and fast shipping, and a money-back guarantee on SS31 Elamipretide Peptides.

Disclaimer:

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Frequently Asked Questions

Does SS31 Elamipretide affect mitochondrial function?

SS31 Elamipretide has the potential to significantly alter mitochondrial function. SS31 works by improving the efficiency of mitochondrial function and as a result, reducing oxidative stress, and increasing ATP production.

What is another name for the SS31 Elamipretide Peptide?

SS31is also know by Elamipretide, Elamipretida, including 736992-21-5, bendavia, SS-31 peptide Arg-Dmt-Lys-Phe-NH2, SS31 peptide, MTP-131, D-Arg-Dmt-Lys-Phe-NH2, UNII-87GWG91S09, and Ocuvia. [R]

Is SS31 Elamipretide Peptide Safe?

According to research, SS31 Elamipretide Peptide might have advantages beyond those already mentioned. However, there is no hard proof that using SS31 Elamipretide has any short-term advantages, and it is unclear what the compound’s possible long-term impacts would be.

Strength	5mg