Toremifene
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Toremifene – Product Details
Toremifene, sometimes known as toremifene citrate, is an experimental chemical classified as a selective estrogen receptor modulator (SERM). It is primarily being studied for its effects on breast cancer in postmenopausal women. Toremifene works by blocking the effects of estrogen in breast tissue, which can slow or stop the growth of breast cancer cells.
In addition to its possible treatment for breast cancer, toremifene has also been studied for its potential benefits in treating prostate cancer in men undergoing androgen deprivation therapy.
It is important to note that toremifene is only available for research use and should not be used for self-treatment. Buy toremifene citrate for research use only.
- CAS Number: 89778-27-8
- Molar Mass: 405.91 g/mol
- Chemical Formula: C26H28ClNO
- IUPAC Name: (Z)-2-[4-(1,2-Diphenylbut-1-enyl)phenoxy]-N,N-dimethylethanamine
- Synonyms: Toremifene citrate, Fareston, FC 1157a, NDC 65483-011-10, Z-Toremifene, (Z)-Toremifene
- Solubility: Depends on the method of study (in vivo or in vitro); Possibly soluble but saturation unknown [R]
What is Toremifene?
Toremifene is an abridged selective estrogen receptor modulator (SERM) used to treat metastatic breast cancer. It is known for its capability of binding to estrogen receptors in the body, which can help to prevent the growth and spread of cancer cells.
In addition to its allegedly anti-cancer properties, toremifene has also been studied for its potential to prevent treatment-related osteoporosis, a condition that can result from the long-term use of certain cancer treatments. It has been shown to increase bone mineral density in some patients, which may help to prevent bone loss and fractures.
Toremifene has a molecular weight of 598.09 g/mol and a molecular formula of C26H28ClNO. Its saturation is unknown, but it is known to be administered orally.
Overall, Toremifene is an important research chemical for human use for the treatment of metastatic breast cancer, and may also have potential benefits for preventing treatment-related osteoporosis. Its selective estrogen receptor modulator mechanism of action makes it a valuable tool in the fight against certain types of cancer.
Possible Uses of Toremifene
Prevents Treatment-Related Osteoporosis
Toremifene has been shown to increase bone mineral density in postmenopausal women undergoing treatment for breast cancer. This might help prevent treatment-related osteoporosis, which is a common side effect of breast cancer treatment. [R]
Treatment for Prostate Cancer Patients
Toremifene has also been studied for its potential benefits in treating prostate cancer patients undergoing androgen deprivation therapy. It has been shown to inhibit the growth of prostate cancer cells in vitro and in animal models. [R]
May Reduce Chest Pain
A group of researchers implied that Toremifene has been shown to be effective in reducing chest pain in patients with cyclical mastalgia, which is a common breast condition characterized by breast pain and tenderness. [R]
May have Fewer Muscle Cramps
Muscle cramps are a common side effect of aromatase inhibitors, which are a type of medication used in the treatment of breast cancer. Toremifene has been shown to have fewer muscle cramps compared to aromatase inhibitors, making it a more tolerable option for some patients. [R]
Potentially Lower Risk of Blood Clots
Toremifene has been shown to have a lower risk of blood clots compared to tamoxifen, another selective estrogen receptor modulator commonly used in the treatment of breast cancer. [R]
May Reduce Symptoms of Gynecomastia
Toremifene has been shown to reduce the severity of gynecomastia in some patients. Gynecomastia which is another adverse effect of androgen deprivation therapy in prostate cancer patients is an enlargement of breast tissue in males. [R]
How Does Toremifene Work?
Toremifene is a selective estrogen receptor modulator (SERM) that binds to estrogen receptors in the body, particularly those that are estrogen receptor-positive. When Toremifene binds to these estrogens, it can have different effects depending on the location and context within the body. In some tissues, Toremifene can act as an estrogen agonist, while in others it can act as an antagonist.
In very few human clinical trials, Toremifene is typically administered orally and is absorbed through the gastrointestinal tract. Once in the body, Toremifene can inhibit the growth and proliferation of estrogen receptor-positive breast cancer cells, making it an effective drug for this type of cancer.
However, Toremifene can also have side effects, including irregular heartbeat, which can be harmful to some individuals. Therefore, it is essential to carefully consider the risks and benefits of Toremifene in one’s research and to work closely with a healthcare provider to monitor any potential adverse reactions or interactions with other medications.
Safety and Side Effects
Toremifene is generally safe when taken as intended through oral administration as exhibited by selected test subjects.
However, some test subjects may experience signs of adverse effects resulting from its use. Common side effects include nausea, swelling, and muscle cramps. In rare cases, Toremifene use may lead to breathing problems, which can be serious and require immediate medical attention.
Frequently Asked Questions
How is Toremifene administered?
Toremifene is typically administered orally, in the form of a tablet or capsule.
Is Toremifene safe to use during pregnancy?
No, Toremifene should not be used for pregnant test subjects as it may be harmful to the developing fetus.
Can Toremifene be used by men?
Yes, Toremifene may also be used in men with breast cancer, or in men with prostate cancer who are undergoing androgen deprivation therapy.
What is the difference between Toremifene and Toremifene Citrate?
Toremifene is the active pharmaceutical ingredient (API) in Toremifene citrate. Toremifene citrate is a salt form of Toremifene, which is commonly used in pharmaceutical formulations. The addition of citrate to the Toremifene molecule makes it more water-soluble and easier to administer orally in tablet or capsule form.
Therefore, Toremifene citrate is the form of Toremifene that is most commonly used in clinical settings for the treatment of metastatic breast cancer and other conditions. While Toremifene and Toremifene citrate have the exact mechanism of action and therapeutic effects, Toremifene citrate is the more commonly used form due to its improved solubility and ease of administration.
Why Buy Toremifene from Behemoth Labz
Behemoth Labz is the best place to purchase Toremifene online.
We have been around since 2014, supplying the highest-quality research compounds money can buy. All of our products come with a 100% satisfaction guarantee, free and fast shipping, and a money-back guarantee on Toremifene.
Summary
Toremifene, which may belong to selective estrogen receptor modulators, is commonly being investigated as a potential treatment of metastatic breast cancer in research studies. One study found that Toremifene administration in ovariectomized female SCID mice increased bone mineral density and prevented treatment-related osteoporosis.
Additionally, Toremifene has demonstrated potential benefits for prostate cancer patients and may increase bone mineral density in test subjects undergoing androgen deprivation therapy. Another study showed that Toremifene inhibited the growth of breast cancer cells and demonstrated an additional benefit in combination with other compounds.
Although the saturation of Toremifene in humans is unknown, the research chemical has demonstrated potential benefits for test subjects with estrogen receptor-positive breast cancer and may reduce the risk of breast cancer recurrence. Toremifene can be administered orally and has been associated with fewer adverse effects than other medications, although patients should still be aware of potential side effects such as irregular heartbeat, chest pain, muscle cramps, nausea, and swelling.
Overall, Toremifene shows promise in the prevention and treatment of breast cancer and may have additional benefits for individuals with prostate cancer and those at risk for treatment-related osteoporosis. While more research is needed to fully understand its mechanisms and potential applications, Toremifene is a promising compound for future study and clinical use.
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