Delta Sleep-Inducing Peptide (DSIP) is a naturally produced compound. Scientific investigations have indicated its potential to extend overall sleep duration and enhance the quality of sleep, particularly in subjects experiencing insomnia. Moreover, DSIP has demonstrated the capacity to shorten the time it takes to fall asleep and decrease instances of waking up during the night.
Furthermore, DSIP has displayed the capability to enhance daytime functionality in individuals diagnosed with narcolepsy, a persistent neurological condition characterized by excessive daytime sleepiness. These findings have led to the hypothesis that DSIP might play a role in regulating the patterns of sleep and wakefulness.
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DSIP, or Delta Sleep-Inducing Peptide, is a naturally occurring peptide that was discovered in the 1970s. It has been studied for its potential role in regulating sleep patterns and promoting deeper, more restful sleep. While its exact mechanisms are not fully understood, DSIP is known for its ability to influence the sleep-wake cycle, particularly in animal studies. It may help induce and enhance the delta sleep phase, which is associated with the deepest and most restorative sleep. DSIP is also of interest in the field of peptide research, and its physiological effects are a subject of ongoing scientific investigation.
Please note that the information provided here is solely for educational purposes and is not intended as medical advice. Behemothlabz offers DSIP for laboratory, educational, and scientific research purposes exclusively.
In a controlled study, DSIP injections (30 nmol/kg body weight) led to a 22.5% increase in sleep time compared to baseline, along with a 26.8% improvement in sleep efficiency. Sleep latency and awakening after sleep onset were reduced by 53% and , respectively. [R]
Another investigation involving chronic insomniac patients reported improved sleep efficiency, shorter sleep latency, and reduced subjective tiredness within the DSIP group. [R]
Three phase-1 studies exploring DSIP’s impact on healthy volunteers revealed enhanced sleep, sustained effects on sleep function for up to 20 hours post-injection, and a well-tolerated profile with no adverse effects. [R]
A preclinical study demonstrated that DSIP increased deep slow wave sleep (S2) while decreasing light slow wave sleep (S1). REM and NREM sleep cycles remained unaffected. [R]
A clinical investigation compared DSIP levels in the cerebrospinal fluid (CSF) of healthy volunteers and patients with schizophrenia, as DSIP neuropeptide can influence central nervous system functioning. The study found significantly lower CSF DSIP levels in schizophrenia patients. [R]
Similarly, the study examining CSF DSIP levels compared healthy volunteers with patients suffering from major depressive disorder (MDD). Patients with MDD had significantly lower CSF DSIP levels, and these levels were inversely correlated with sleep disturbance scores in depressed patients. [R]
Another study investigated plasma DSIP levels in suicidal MDD patients and reported significantly elevated DSIP levels in this group. A significant correlation was established between cortisol (the “stress hormone”) and DSIP levels in healthy controls. [R]
Narcolepsy is characterized by daytime drowsiness and sudden sleep episodes. Research on a male narcoleptic individual showed that repeated DSIP injections, either in the evening or morning, enhanced daytime activity, reduced the frequency of sleep attacks, and improved daytime performance. [R]
In a clinical study, 6 out of 7 patients with chronic pain syndromes responded positively to DSIP therapy. These patients experienced relief from various discomforts, including migraine headaches, vasomotor headaches, foot pain of psychogenic origin, and tinnitus. [R]
Patients reported reduced pain perception and improved mood, with these improvements persisting for up to 91 days. Pain perception was assessed using a visual analog scale.
DSIP has been studied for its potential to influence sleep patterns, particularly in animal studies. It is associated with promoting deeper and more restful sleep, but its exact mechanisms are still being explored.
DSIP has been studied in relation to sleep regulation, its effects on various sleep phases, and its potential role in conditions like insomnia, schizophrenia, major depressive disorder, and narcolepsy. Further research may explore additional applications.
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Strength | 50mcg per spray/5mg/10ml |
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