Epithalon

Epithalon (Peptide) – Product Information

• This peptide is offered as 100mg

Among the many research peptides that could promote quality health, epitalon peptide is known to address aging by improving the longevity of human cells.

Like epithalamin, a polypeptide extract of the human pineal gland, epithalon extends the lifespan of mice and fruit flies while also restoring the circadian rhythms of melatonin and cortisol production in elderly rhesus monkeys.

At the same time, peptide epitalon makes the eye retina of Campbell rats with retinitis pigmentosa work better.

Researchers are still doing clinical trials to find out how epithalon can help the body deal with getting older and what other health benefits it might have.

• CAS Number is stated as 307297-40-1
• Molar Mass is 390,35 g·mol−1
• It has a Chemical Formula of C14H22N4O9
• IUPAC Name:(4S)-4-[[(2S)-2-aminopropanoyl]amino]-5-[[(2S)-3-carboxy-1-(carboxymethylamino)-1-oxopropan-2-yl]amino]-5-oxopentanoic acid
• Also known by Synonyms as Epithalone

The Epithalon for sale from BehemothLabz is intended for laboratory research use only, and is not for human consumption.

Peptides in lyophilized powder form above 50mg may need a higher volume of bacteriostatic water to fully dissolve. Using too little water can result in some powder remaining undissolved.

What is Epithalon?

Epithalon (Ala Glu Asp Gly) (also known as epitalon, epithalone, and epithalamin) is a synthetic counterpart of the pineal gland peptides epithalamin, a polypeptide.

How does Epithalon Work?

Epitalon is a man-made peptide that is similar to epithalamin, which is a natural peptide that is found in the pineal gland of mammals and has anti-aging properties. Research has shown that epithalamin can lower the number of animals that die, lower the number of free radicals, and change the way catalase works to stop tissue damage. [R]

Epithalamin has been shown to add 52% more years to the lives of fruit flies, 52% more years to the lives of normal rats, and 27% more years to the lives of mice that are more likely to get certain types of cancer and heart disease. [R]

Epitalon, also known as the “Fountain of Youth” since it is supposed to address aging, is a tetra-peptide comprised of four amino acids. These are the amino acids alanine, glutamic acid, glycine, and aspartic acid.

During telomerase activity, the peptide controls cell cycle progression. Telomerase is an enzyme that elongates chromosomes by combining protein and RNA subunits.

Telomeres shorten as humans age, resulting in chromosome shortening and decreased cell division and growth. Epitalon can reverse the aging process by lengthening telomeres via telomerase.

 

Epithalon Research

Numerous animal and cell-based studies on Epithalon have been conducted. Clinical research has also been conducted on this research chemical. All of these studies indicate that Epithalon slowed spontaneous tumors, helps reproductive and immune systems, decreases tumor growth improves youthful appearance, etc.

However, in the absence of randomized, large-scale, placebo-controlled trials, the FDA is yet to approve Epithalon for human consumption. Therefore, Behemoth Labz sells Epithalon for laboratory and research purposes, not for human use.

 

Epithalon and on-reproductive age women (age-related diseases)

The in vitro experiments study aims to examine the potential of Epitalon, a peptide with anti-aging properties, to delay oocyte aging in vitro. Oocyte aging is a critical issue that affects embryo development and the success of assisted reproductive technology (ART) in humans. Using fresh oocytes and spermatozoa in ART and developing reliable methods to control oocyte aging are crucial to improving its success.

The study’s findings reveal that Epitalon can protect ovulatory oocytes from post-ovulatory aging by decreasing oxidative stress. This discovery suggests that Epitalon treatment may increase the chances of successful fertilization using intracytoplasmic sperm parenteral solution (ICSI).

However, the study acknowledges that additional research is necessary to evaluate whether Epitalon can enhance oocyte quality and improve conception rates for women of non-reproductive age. [R]

Anti-Aging Effects and Telomerase activity

According to research, the epitalon peptide can extend the lifespan of insects and animals by delaying the aging process. At a minimum, epitalon’s ability to eliminate free radicals in the body is responsible for its profound effects.

Particular research indicates that epitalon treatment activates an enzyme called telomerase that safeguards the telomere (end of human chromosomes critical to guaranteeing DNA well-being). [R]

When the epitalon activates the telomerase, the immediate result is a decrease in how many errors a DNA strand has, thus proving that the epitalon protects the DNA. [R]

 

Epithalon and Skin Health

EEpitalon could also have a positive effect on particular genes, such as the one that controls MMP2. Rat studies identify epitalon-activating fibroblasts, the cells that produce and maintain extracellular matrix components such as collagen and elastin. Collagen and elastin collaborate to promote skin health by imparting elasticity and a youthful appearance.

30–45 % more fibroblasts were activated in mice that had been exposed to epitalon.

 

Epithalon and Melatonin Production

Pineal gland-produced melatonin is a hormone that may function to improve sleep quality and slow aging.

Specific research among mice demonstrates that epitalon peptide and other research chemicals influence the synthesis and release of melatonin by stimulating the expression of two known proteins. [R]

 

Epitalon and Anti-Tumor Effects

Cancer is an additional possibility involving synthetic pineal peptide epitalon. It has been discovered that rats receiving a daily dose of epitalon exhibit decreased tumor growth.[R]

Researchers provide evidence that epitalon activates a specific gene for the circadian rhythm-regulating protein PER1, which is absent in patients with certain cancers. This indicates that, given more time, epithalon could be a treatment for cancer.

In an in-vitro study, the effects of two peptides, Epithalon peptide, and Vilon, were tested on mice with the HER-2/neu gene that are more likely to get breast cancer. Researchers discovered that treatment with Epitalon significantly decreased the number and maximum size of tumors, as well as the number of lung metastases. In addition, treatment with Epitalon decreased HER-2/neu mRNA expression in mammary tumors. In contrast, treatment with Vilon was associated with adverse effects, such as an increased incidence of mammary cancer development and a shorter mean latent period for tumors. Epitalon inhibits the development of spontaneous mammary tumors in HER-2/neu mice, suggesting that the antitumor effect of the peptide is at least partially due to the downregulation of HER-2/neu gene expression in mammary adenocarcinoma. [R]

Further research is suggested in order to fully understand the effect in human somatic cells and prove it can really reduce spontaneous tumor incidence.

Epithalon and DNA Activation

As one of the leading anti-aging research chemicals, epithalon interacts directly with the DNA, as suggested by this study. [R] Below are the epitalon peptide’s known DNA interactions:

1. pCREB t – Regulation of the circadian rhythm
2. Tram 1 – Promotes the synthesis of proteins
3. Telomerase – The activity of telomerase increases the longevity of cells.
4. CD5 – Responsible for immune cell differentiation

It should come as no surprise that epithalon supports the immune system. The polypeptide hormone increases interferon-gamma expression in aging lymphocytes, according to mouse clinical trials. The immune system contains the signaling molecule interferon-gamma. Activating macrophages, natural killer cells, and T cells protect against viral infections.

 

Frequently Asked Questions (FAQs)

Who discovered epithalon?

Vladimir Khavinson, a professor, is credited with discovering the epithalon. He is the main gerontologist for the Health Committee of the Government of Saint Petersburg as well as the director of the Saint Petersburg Institute. He is a Russian scientist and vice president of the Gerontological Society of the Russian Academy of Science. He devoted the last 35 years of his life to conducting epitalon-related research in animal clinical trials, most frequently among mice.

 

Is epitalon a peptide?

Yes, epithalon is among the peptides being researched for human consumption safety. Like other peptides such as BCP 157 and Ipamorelin, Epitalon mimics a naturally occurring enzyme in the body.

 

What are Peptides?

Peptides are fragments of proteins with a smaller size. Numerous health and beauty products contain peptides due to their anti-aging, anti-inflammatory, and muscle-building properties. It is believed that Epithalon, one of the many peptides used in research today, slows the anti-aging process in body cells.

 

What is the Pineal Gland?

The pineal gland, also known as the pineal body, is a microscopic gland located in the brain. The melatonin-producing gland is an endocrine gland. By secreting melatonin, the pineal gland aids in the regulation of the circadian cycle of sleep and wakefulness.

 

Is epitalon safe for human consumption?

No. Epithalon is still the subject of extensive study, which necessitates an in-depth analysis to determine how it affects the entire body of its subjects.

Is Epithalon legal?

Epitalon is not currently approved by the United States Food and Drug Administration (FDA) for medical use, and it is not available by prescription in the United States. However, as a research chemical, it may be legally available for purchase in the United States for scientific and experimental purposes.

Where to Buy Epithalon for Sale?

BehemothLabz is the best place to buy Epithalon online.

We have been around since 2014, supplying the highest-quality research compounds money can buy. All of our products come with a 100% satisfaction guarantee, free shipping, and a money-back guarantee. 

 

Epithalon Summary

Epithalon is a man-made peptide that mimics the effects of epithalamin, a natural peptide found in the pineal gland of mammals that has anti-aging properties. Epithalon works by controlling the cell cycle progression during telomerase activity, which can elongate chromosomes and reverse the aging process by lengthening telomeres. Although it has been shown to have anti-aging effects, Epithalon has not yet been approved for human consumption by the FDA and is only sold for research purposes. The peptide has shown potential in delaying oocyte aging, improving skin health, promoting melatonin production, and having anti-tumor effects. Further studies are needed to evaluate its effectiveness in treating age-related diseases and improving conception rates.

 

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Variation	100mg

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