Exemestane

Exemestane – Product Details

Exemestane is an oral tablet that belongs to a class of drugs called aromatase inhibitors. In different research subjects, its has been shown to irreversibly binding to the aromatase enzyme, and block the conversion of androgens to estrogens. 

Exemestane has been found to support osseous tissue mineralization and decrease the risk of osteoporosis in different research subjects.  

Exemestane is a research chemical that needs more in-depth research studies. 

• CAS Number: 107868-30-4
• Molar Mass: 296.41 g/mol
• Chemical Formula: C20H24O2
• IUPAC Name: 6-Methylenandrosta-1,4-diene-3,17-dione
• Also known by Synonyms: Aromasin, 6-Methyleneandrosta-1,4-diene-3,17-dione, Exemestanum, Exemestane 25mg

How Does Exemestane Work?

Exemestane is an aromatase inhibitor that works by binding to the substrate-binding part of the aromatase enzyme. It forms covalent bonds which leads to irreversible inactivation of the enzyme. This inhibition is being seen to occur in research subjects, primarily in their adrenal glands, and adipose tissue. By blocking aromatase, exemestane reduces the conversion of androgens such as testosterone to estrogens. 

Animal test subjects have demonstrated that exemestane is highly selective for aromatase and does not significantly affect other enzymes involved in steroidogenesis.

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