GHRP-2 is a synthetic growth hormone secretagogue. Research has shown that it produces a dose-dependent increase in growth hormone secretion in children and adults. It has also been reported to increase appetite, body weight, and feelings of hunger.
In separate clinical studies, GHRP-2 ameliorated anorexia symptoms, increased insulin-like growth factor 1 (IGF-1) levels, and demonstrated cardioprotective effects. A preclinical study has reported that it could attenuate the actions of proteins involved in muscle breakdown.
Behemoth Labz sells GHRP-2 for laboratory and research purposes only.
What is GHRP-2?
Growth hormone-releasing peptide 2 is a synthetic secretagogue for growth hormone. It binds to the ghrelin receptor to stimulate the body’s GH secretion. According to research, GHRP-2 consistently and dose-dependently increases GH levels. [R]
GHRP-2 is by far the most thoroughly studied GHRP. It has been the subject of multiple clinical trials and numerous preclinical studies. This synthetic peptide has also undergone phase II clinical trials as a potential treatment for childhood short stature.
Clinical research has demonstrated that this peptide’s effects extend beyond GH secretion. Additionally, GHRP-2 has been shown to affect appetite, body weight, and feelings of hunger. However, it may not have the same effect on appetite stimulation asGHRP-6. [R]
Scientists theorize that this growth hormone secretagogue may influence pain perception. This is due to its ability to bind to the body’s opioid receptors. GHRP-2 has not yet been approved for medical use anywhere in the world, despite all of its promising effects. [R]
How does GHRP-2 Work?
GHRP-2 stimulates the pituitary gland and hypothalamus to produce growth hormone (GH). This mechanism of action causes the release of growth hormone through three mechanisms: non-GH-releasing hormone (GHRH) receptors, non-GHRH intracellular mechanisms, and endocrine mechanisms.[R]
Numerous animal and cell-based studies on Epithalon have been conducted. Clinical research has also been conducted on this research chemical. All of these studies indicate that GHRP-2 improves growth hormone deficiency, appetite, anorexia, muscle growth performance, pain perception overcome natural growth plateaus, etc
However, in the absence of randomized, large-scale, placebo-controlled trials, the FDA is yet to approve GHRP-2 for human consumption. Therefore, Behemoth Labz sells GHRP-2 for laboratory and research purposes, not for human use.
1) GHRP-2 and Growth Hormone Deficiency
A deficiency in growth hormones is a life-altering condition. GHD is characterized by a decrease in muscle mass, an increase in fat mass, and an increased risk of mortality. [R]
A small clinical trial has validated the use of GHRP-2 for diagnosing GHD in adults. The study found that the reproducibility of the GHRP-2 test for detecting GHD was satisfactory. Importantly, it was only moderately affected by age and obesity. [R]
In another clinical trial, administration of GHRP-2 resulted in a 4.5-fold increase in adults (median age: 22) with this condition. Children treated with this peptide had a dose-dependent increase in overnight GH secretion, according to a third study. [R] [R]
2) GHRP-2 and Appetite
Multiple clinical studies have demonstrated that GHRP-2 stimulates hunger.
According to a 2005 study, GHRP-2 treatment increased the food intake of healthy men. In comparison to their counterparts in saline, the GHRP-2 group consumed up to 45 percent more food. According to body weight-based calculations, each member of this peptide’s treatment group ate more. [R]
Another study revealed that the effects of GHRP-2 on appetite stimulation may not be limited to healthy individuals. It was discovered that this synthetic peptide increased hunger, decreased early satiety, and improved food intake in anorexic patients.[R]
3) GHRP-2 and Anorexia
Anorexia is an eating disorder characterized by an intense fear of weight gain. People with this condition do not consume enough food, resulting in an abnormally low body mass index.
health of an anorexic patient. This artificial peptide increased the patient’s body mass, muscle mass, and muscular strength. Following the administration of GHRP-2, both their physical and mental activities improved. [R]
4) GHRP-2 and Muscle Growth
Two preclinical studies have demonstrated the muscle-building benefits of GHRP-2.
According to the first study, this synthetic growth hormone levels secretagogue inhibited the activity of two proteins involved in muscle breakdown. [R]
In a separate study, feeding GHRP-2 to yaks increased their skeletal muscle area and myofiber diameter. Additionally, it was discovered that this synthetic peptide upregulated protein synthesis pathways in order to increase muscle protein deposition. [R]
5) GHRP-2 and Pain Perception
Most opioid pain medications alter pain perception by binding to pain receptors. Selective opioid receptor agonists are used clinically for pain management, anesthesia, and addiction treatment.
Initial evidence suggests that GHRP-2 may also exert comparable effects on opioid receptors. ICV injections (which bypass the blood-brain barrier) reduced the perception of pain in mice by binding to the opioid receptors responsible for pain relief, sedation, and addiction.[R]
6) GHRP-2 and Heart Health
It has been demonstrated that GHRP-2 exerts antioxidant effects on the heart.
A study on rats revealed that GHRP-2 exerts antioxidant effects on the heart. It was reported that this synthetic peptide inhibited oxidative stress in the heart’s vascular system. GHRP-2 was also found to inhibit the production of peroxides induced by LDL.[R]
In a blood-perfused rabbit heart model, another preclinical study found that pretreatment with GHRP-2 protected against diastolic dysfunction of heart muscle during stunning. [R]
7) GHRP-2 and Growth Retardation
In a study, the effects of giving yaks to overcome natural growth plateaus using GHRP-2 and cysteamine. Many yaks don’t grow as fast as they should because of cold weather, lack of food, malnutrition, different diseases, harsh plateau conditions, and old ways of grazing. The results showed that both treatments of GHRP-2 and cysteamine led to bigger muscles and more weight gain every day. GHRP-2 worked by making protein synthesis pathways more active, while CS did its job by making the ubiquitin-proteasome pathway less active. [R]
It has been reported that a 270-minute subcutaneous infusion of GHRP-2 is safe. Likewise, no adverse effects were reported following subcutaneous administration for 30 days. Also deemed safe was a 12-month oral administration of GHRP-2 in children. [R]
Frequently Asked Questions (FAQs)
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We have been around since 2014, supplying the highest-quality research compounds money can buy. All of our products come with a 100% satisfaction guarantee, free shipping, and a money-back guarantee.
What is the half-life of GHRP-2?
GHRP-2 has a biological half-life of about 30 minutes. [R]
Does GHRP-2 improve sleep quality?
A clinical study involving healthy young men demonstrated that GHRP-2 has no effects on sleep. This is in contrast to other growth hormone-releasing peptides, such as GHRP-6, which has been shown to improve the quality of stage 2 sleep in healthy men. [R] [R]
Does GHRP-2 affect lean body mass?
A case study of a person with anorexia that lasted a year showed that GHRP-2 treatment made the person’s muscles grow and get stronger. However, more muscle structure research is needed to fully understand the potential anabolic effects of this novel growth hormone release secretagogue to promote lean body mass.
Where to Buy GHRP-2 for Sale?
Behemoth Labz is the best place to buy GHRP-2 online.
We have been around since 2014, supplying the highest-quality research chemicals money can buy. All of our products come with a 100% satisfaction guarantee, free and fast shipping, and a money-back guarantee on GHRP-2.
Growth hormone-releasing peptide 2 (GHRP-2) is a synthetic novel growth hormone secretagogue receptor that stimulates the pituitary gland and hypothalamus to produce growth hormone. Its effects include increased GH levels, appetite stimulation, muscle growth, and pain relief. Clinical studies have validated its use for diagnosing growth hormone deficiency and improving the health of anorexic patients. GHRP-2 has also demonstrated antioxidant effects on the heart, protected against diastolic dysfunction during stunning, and improved growth retardation in yaks. However, it has not yet been approved for human consumption as it is recommended for more research to be done.
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