What are peptides?

Peptides are short-chain amino acids that are found naturally in the human body. Amino acids are the building blocks of protein and these amino acids are specifically designed to regulate certain functions within the human body.

Peptides are used as a mode of therapy that are used to take existing sequences and rewrite to potentially regulate and rejuvenate functions. In simpler terms, they bind to and tell other cells what to do, mimicking or replacing the functions of the naturally occurring peptide. Peptides may have the ability to rewrite body chemistry to promote homeostasis, restoration and anabolism.


PT-141 is a peptide that was developed based on Melanotan 2, which is known to be a synthetically produced variant of a peptide hormone. This is naturally produced in the human body and stimulates melanogenesis, also known as the alpha-melanocyte-stimulating hormone.

PT-141 was designed to be an effective and efficient treatment for both erectile dysfunction and increased libido for males and to potentially improve female sexual arousal disorder in females. It is deigned to work directly through the nervous system to potentially increase arousal, desire, and satisfaction with sex.

PT-141 and its potential to increase libido

 Studies have shown that the PT-141 has the potential to provide libido-enhancing effects through its ability to activate melanocortin receptors MC1R and the MC4R without tanning your skin. This makes it quite different to the very popular Melanotan 2 peptide. These results might also provide a potential remedy for the treatment of female sexual dysfunction and male erectile dysfunction [R]. 

As mentioned above, PT-141 binds the melanocortin 4 receptor (MC-4R) and the MC-4R, which produces central arousal in the central nervous system.This may influence sexual behavior and libido which can create sexual arousal in both men and women.

 PT-141 and Hemorrhage

 The PT-141 is being researched as a potential alternative treatment for acute bleeding. Through binding both the MC-1R and the MC-4R, a modified version of the PT-141 may reduce ischemia. This has massive implications as it could potentially protect tissues against the inadequate blood supply in the setting of hypovolemic shock [R].

PT-141 and Infection

Studies investigating fungal infections,found MC-1R to possess significant anti-fungal and anti-inflammatory properties. In the future, PT-141 may potentially be considered an alternative treatment in fungal infections because of its ability to activate the MC-1R [R].

PT-141 Research Peptide

  • CAS Number is stated as 189691-06-3
  • Molar Mass is 182g·mol−1
  • It has a Chemical Formula as C50H68N14O10
  • IUPAC Name: (3S,6S,9R,12S,15S,23S)-15-[[(2S)-2-acetamidohexanoyl]amino]-9-benzyl-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxylic acid;acetic acid
  • Also known by Synonyms as Bremelanotide Acetate

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