Similar to Cardarine, SR 9011 is a research chemical known as a Rev-ErbA agonist, which means it works by binding to Rev-ErbA receptors in the body. Rev-erb α, known as nuclear receptor 1D1 (NR1D1), regulates circadian rhythm, modulates glucose and lipid metabolism, and inflammatory response. [R]
This compound is being studied for its potential to have a drastic effect on the body’s rate of metabolism, muscular and cardiovascular endurance, and the way the body uses energy stores.
Keep contents tightly sealed and stored in a cool dry place. Items are shipped in a plain envelope or bubble mailer within 24-48 hours (or the next business day).
The SR 9011 from Behemoth Labz is designed for laboratory research use only and is not intended for human consumption.
As mentioned above, SR 9011 is a Rev-ErbA agonist. This means it has the ability to bind to specific receptors that regulate important functions in the human body. It is currently used in research studies to achieve fat loss, build muscle, and enhance endurance in laboratory mice. [R]
However, no clinical trials have been reported to date and as such this compound is not approved for human consumption.
SR 9011 is often associated with selective androgen receptor modulators (SARMs). However, unlike a SARM, SR 9011 works by upregulating the functioning of Rev-Erba proteins. This means SR 9011 has the potential to increase the constitutive repression of genes regulated by Rev-ErbA and Rev-ErbAB (Beta).
A repressor, like SR9011, works by inhibiting gene expression. This may produce results of hormone and metabolic modulation.
SR9011 may stack well in research with:
No clinical trials on the effects of SR 9011 have been done to date. However, numerous animal studies have shown some potential benefits including:
A recent study on diet-induced obese mice treated with SR9009 and SR 9011 (i.e., two times a day for 30 days) have been reported to display decreased fat mass and markedly improved dyslipidemia and hyperglycemia. The activation of REV-ERB leads to the enhancement of circadian rhythm observed in mice. This affects behavior, sleep cycle, and some functions related to increment in energy production. [R]
A 2018 animal study found that SR9011 induced apoptosis (cell death) in a range of cancer cell lines that include melanoma, leukemia, brain, breast and colon cancers, and in cells driven by different oncogenes. [R]
The immune cells of the brain are called microglia. Hyperactivation of these cells contributes to the pathology of metabolic and neuroinflammatory diseases.
A cell-based study was conducted to determine the potential effect of SR9011 on the immune response and cell metabolism of these microglia cells. Results from this study showed that the research chemical has the potential to aid the treatment of neuro-inflammatory diseases. [R]
Myocardial infarction, also known as a heart attack, occurs when the heart doesn’t receive enough oxygen. A study investigating the effects of SR9009 and SR9011 on the progression of myocardial infarction and heart failure in mice found some interesting results.
Both were reported to potentially improve hyperglycemia, dyslipidemia, and skeletal muscle oxidative capacity. [R]
Yes. However, SR9011 is only legal to buy or sell for laboratory research use only. As stated by the FDA, it is illegal to buy as a supplement.
SR9011 has a relatively short half-life of 4 hours.
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15ml / 17mg per ml / 250mg, 30ml/ 33mg per ml / 1000mg