TB-500 is offered in 2 variants: 5mg and 10mg.

What are peptides?

Peptides are short-chain amino acids that are found naturally in the human body. Amino acids are the building blocks of protein and these amino acids are specifically designed to regulate certain functions within the human body.

Peptides are used as a mode of therapy that are used to take existing sequences and rewrite to potentially regulate and rejuvenate functions. In simpler terms, they bind to and tell other cells what to do, mimicking or replacing the functions of the naturally occurring peptide. Peptides may have the ability to rewrite body chemistry to promote homeostasis, restoration and anabolism.


 TB-500 is a synthetic replica of Thymosin Beta 4, a protein peptide that occurs naturally in the bodies of both animals and humans. Thymosin Beta 4 plays a pivotal role in increasing angiogenesis (formation of new blood vessels) in dermal tissues. [R]

TB-500, like Thymosin Beta 4, consists of 43 amino acids and as a synthetic peptide was originally developed for veterinary purposes.It is claimed to offer various therapeutic benefits to a racehorse. In horse racing, TB 500 is shown to have a significant effect on the reduction of inflammation and the inhibition of adhesions from injury. [R]

TB 500 and its Potential Effects on Heart Health

In a clinical phase 2 trial, TB4 was found to reduce the volume of scars after a heart attack. The trial was conducted on patients with acute myocardial infarction (MI), the leading cause of cardiac death worldwide. It was confirmed that TB4 could potentially protect and repair the heart. [R]

In an animal study, TB4 treatment improved left ventricular function and reduced cardiac remodeling after myocardial infarction [R].

Additionally, a study has highlighted multiple functions TB4 plays in the protection, repair, and regeneration of the mammalian heart. It has been shown to promote cell survival, modulate the ischemic heart’s inflammatory environment, and reactivate the dormant epicardium. [R]

Can TB-500 Potentially Influence Muscle Growth

Treatment of mice with TB4 didn’t ameliorate the metabolic disruptions associated with diet-induced obesity. Nor did it enhance muscle regeneration. However, TB4 increased osteoblast proliferation and neurite outgrowth, consistent with its WADA classification as a prohibited growth factor.

Furthermore, a cell-based study found that muscle injury enhances the location production of Thymosin Beta 4, thereby promoting the migration of myoblasts to facilitate skeletal muscle regeneration. [R]

TB-500 Research Peptide

  • CAS Number is stated as 885340-08-9
  • Molar Mass is 890g·mol−1
  • It has a Chemical Formula as C38H67N9015
  • IUPAC Name: N-acetyl-L-leucyl-L-lysyl-L-lysyl-L-threonyl-L-alpha-glutamyl-L-threonyl-L-glutamic acid
  • Also known by Synonyms as Thymosin Beta 4

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5mg, 10mg


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