Andarine vs Ostarine | Which Option is Better

In recent years, there has been more focus on SARM studies due to their lower side effects compared to anabolic steroids. As SARMs are frequently used in research studies, a debate about Andarine vs. Ostarine may arise when choosing a better one for the study. 

Both SARMs provide better results in terms of their benefits. However, there are certain differences as well. This blog provides a detailed comparison of Andarine and Ostarine for better understanding. 

Understanding Ostarine and Andarine 

Andarine (S4) is a stronger SARM that may help in muscle-building, promoting bone health, and reducing fats as per studies on animals. It has a strong affinity for androgen receptors with high bioavailability and tolerability. S4 Works by selectively targeting androgen receptors like other anabolic steroids but it has fewer side effects than steroids. Unlike steroids, it does not convert to estrogen or significantly disrupt hormonal levels. 

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In contrast, Ostarine is the most studied and researched SARM. It is also known as MK-2866 and is helpful in boasting similar effects as Andarine but with fewer side effects. Also, it works the same way Andarine does by selectively targeting androgen receptors to promote muscle growth and increase recovery in research subjects. Similarly, it is relatively safe to use as compared to S4 and is currently studied for the treatment of osteoporosis and bone-wasting diseases in subjects. 

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Some key differences in benefits, structure, half-life, and side effects set both of these SARMs apart from each other. These are discussed here in detail.

Andarine Vs Ostarine – Benefits 

Let’s discuss the benefits of both SARMs.

1. Building Muscle Mass 

Both SARMs have been shown to preserve muscle mass and build lean muscle mass in research subjects.  However, there is no big difference as Ostarine has been reported to increase 2-3 pounds while the same dose of Andarine increases 3-4 pounds in research subjects. 

Similarly, during a cutting cycle, Andarine has been proven to preserve more lean muscle as compared to Ostarine in subjects. However, research has shown that exercise and a proper diet are mandatory for muscle building. 

2. Fat Loss 

In vascularity and fat loss, Andarine is noted to have a superior edge as compared to MK-2866. The real battle begins here. Although both SARMs help with losing extra fats, Ostarine is less effective in fat reduction as shown by various clinical investigations. 

3. Gaining Strength

According to clinical studies, these two SARMs are less effective in strength gains. Nevertheless, Ostarine and Andarine have a muscle-increasing quality that gives power and strength to subjects. However, their effects on increasing strength are similar. 

Half-life Differences 

Ostarine is easier to dose than Andarine because of the high half-life in subjects. Studies show that Ostarine has 24 hours of half-life and requires one daily dose. 

Conversely, Andarine has a half-life of 4 hours and requires multiple daily doses in research subjects.

Andarine Vs. Ostarine – Results

Andarine and Ostarine show the same results when investigated in clinical studies. However, S4 delivers quicker and faster results as compared to Ostarine.  For example, when a similar dose is administered to the research subject for muscle building, Andarine will add bulk to muscles quicker than MK-2866. 

Similarly, some results from a study show that in a normal Ostarine cycle, a subject may lose 3% of body fats. While in one cycle of Andarine, a subject may shed about 4% of body weight. This shows that Andarine has been proven stronger than MK-2866. 

Structure of Andarine and Ostarine

Both SARMs are also different in their molecular and crystal structure. Clinical studies show that one molecule of Ostarine crystalizes into the P21 space group with Z = 2 in the monoclinic system. While one molecule of Andarine crystalizes into the P42212 space group with Z = 8 in the tetragonal system. 

In addition, Ostarine has hydrogen bonds as O-H⋯N and N-H⋯O while Andarine has O-H⋯O, N-H⋯O types of hydrogen bonds. 

Andarine Versus Ostarine – Side Effects 

As far as the side effects of these SARMs are concerned, Ostarine is generally considered safer because it has fewer adverse effects than S4 in research subjects. Some potential risks associated with both of the SARMs are given below. 

• Impaired Vision: Ostarine has no adverse effects on vision. On the other hand, Andarine has been found to cause vision impairment in subjects. Studies show that S4 causes a yellow tint in the peripheral area of the eyes which hinders vision. This may occur in the case of high use of Andarine. 
• Suppression: While both of these SARMs cause mild suppression, Andarine may cause more suppression than Ostarine. 

Summarizing Andarine in contrast to Ostarine 

Features	Andarine	Ostarine
Benefits	Faster	Slower
Side Effects	More	Less
Half-life	4 hours	24 hours
Recovery	Less intensive	More intensive
Research Study	Not studied much	Highly studied

Which One is better, SARM?

The best choice between Andarine and Ostarine depends on the research study, objective, and preference. If you need a mild SARM to investigate its benefits such as muscle building then select MK-2866 because S4 is more powerful and intensive than MK-2866. But if you need strong SARM for your study, then go for Andarine. 

Conclusion 

Andarine and Ostarine both have positive impacts on mass building and fat loss in research subjects. Both have shown the same benefits in research investigations but Andarine has been superior out of both SARMs. However, Ostarine shows mild side effects in subjects compared to S4. Choosing the better SARM for research investigation depends on the research objectives and type of study. 

FAQs 

What is the best place to buy Andarine and Ostarine Online?

If you want to study Andarine and Ostarine for research purposes, the best place where you can buy them online is Behemoth Labz. It not only ensures pure and active products but also provides trusted and reliable Customer services. Consider Behemoth Labz for S4 and Ostarine and get optimal results from your studies.

What is the main difference between Andarine and Ostarine?

The main difference between Andarine and Ostarine lies in their side effects. MK-2866 has minor side effects while the latter shows some adverse side effects as per research subjects. 

Does Ostarine increase bone density?

Yes, according to research studies on animals, Ostarine may increase bone density, especially when used for preventative measures. 

Will Ostarine Increase Endurance?

Yes, clinical studies show that Ostarine may increase endurance in subjects. 

Are there any similarities between Andarine and Ostarine?

Yes, there are some similarities between Andarine and Ostarine. For example, both SARMs have the same mechanism of action and benefits with different intensities in research subjects.  

Can you stack Andarine with Ostarine?

Yes, you can stack Andarine with Ostarine. According to a research study, Andarine (50mg) can be stacked with Ostarine (25mg) and Cardarine (20 mg) when used for 9-12 weeks in subjects. 

References 

1. Turza, Alexandru, et al. “Crystal and molecular structure of ostarine and andarine.” Journal of Molecular Structure 1199 (2020): 126973.
2. Miklos, Amalia, et al. “LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY METHODS FOR THE DETERMINATION OF ANDARINE AND OSTARINE IN RAT SERUM AFTER PROTEIN PRECIPITATION.” Farmacia 67.5 (2019): 772-779.
3. Singh, Shivani. “MK-2866 (Ostarine) SARM Review: Benefits, Side Effects, & More.”