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Cardarine, or GW-501516, is a PPAR agonist. Clinical research involving Caucasian men (age 18-50 years) has shown that Cardarine has the potential to ameliorate multiple metabolic abnormalities, including oxidative stress, dyslipidemia, obesity, and insulin resistance.
Animal research has demonstrated that Cardarine may enhance running endurance, fatty acid oxidation, and HDL cholesterol levels. GW-501516 has also been found to have the potential ability to lower LDL cholesterol, fasting triglycerides, and fasting insulin levels in intact mice.
Behemoth Labz sells Cardarine for laboratory research use only.
If you’re not interested in Cardarine liquid, we also have injectable Cardarine here.
Keep contents sealed and stored in a cool dry place. Items are shipped in a plain envelope or bubble mailer within 24-48 hours (or next business day)
Cardarine, otherwise known as GW-501516 is a PPAR Delta Receptor agonist, which means it acts on the PPAR Delta receptors.
It was first researched as a potential way to treat cardiovascular and metabolic diseases by GlaxoSmithKline and Ligand Pharmaceuticals before being abandoned during animal studies.
The Cardarine for sale from Behemoth Labz is 3rd party tested for the utmost purity and quality.
Cardarine GW-501516 is a peroxisome proliferator-activated receptor (PPAR) agonist, similar to GW-0742 and Stenabolic.
PPARs are a group of nuclear receptor proteins that regulate cellular differentiation, development, and metabolism. Cardarine is an agonist of PPAR δ, one of three PPAR isotopes. [R][R]
Cardarine was initially developed in the early 1990s as a potential treatment for hyperlipidemia (elevated fats in the blood). Throughout the early 2000s, multiple studies were conducted to examine its potential effectiveness in treating obesity, diabetes, and cardiovascular disease. [R]
Due to its potential role as a performance enhancer, Cardarine was added to its annually released list of banned substances by the World Anti-Doping Agency (WADA) in 2009. At the time of writing, Cardarine GW501516 isn’t approved for human use anywhere in the world. [R]
Cardarine works by binding PPAR δ receptor with high affinity and potency. Its working mechanism distinguishes GW501516 from selective androgen receptor modulators (SARMs), which target/bind androgen receptors (ARs) in the skeletal muscle tissue. [R]
Cardarine has been shown to posses the potential to activate AMP-activated protein kinase, glucose uptake, and fatty acid oxidation in skeletal muscle. It has also demonstrated the potential ability to stimulate fatty acid oxidation and reverse metabolic abnormalities in obese and pre-diabetic individuals.
Cardarine underwent various pre-clinical studies and human trials in the two decades following its development. These studies have shown that Cardarine is potentially capable of ameliorating metabolic disorders, enhancing running endurance, and lowering oxidative stress in the brain.
GW501516 has also been shown to potentially repress inflammation, stimulate fatty acid oxidation, and improve heart health in mice. Aside from that, Cardarine has demonstrated the potential to be beneficial to liver and kidney health in mouse and cell-based studies.
In a study involving Caucasian men (ages 18 – 40), Cardarine treatment ameliorated metabolic abnormalities associated with metabolic syndrome. These include oxidative stress, dyslipidemia (high-fat levels in the blood), obesity, and insulin resistance. [R]
Participants resided in a clinical research facility and were given a standardized diet. Notably, no adverse effects were reported. Additional research on GW501516 is thus warranted since it appears that this research chemical can potentially ameliorate metabolic syndrome features.
A pre-clinical study explored the potential effects of Cardarine on running endurance. Results from the study show that GW501516 treatment showed potential enhanced running endurance. It also potentially increased the proportion of specific muscle fibers in both trained and untrained mice. [R]
Compared to the vehicle control group, only a 1-week GW501516 treatment improved the mice’s running distance by 671.8m (48.6%). Mice who were administered Cardarine for 3 weeks enhanced running distance by 750.3 m (68.6%) compared to untrained control mice.
Oxidative stress occurs when there’s an imbalance between antioxidants and free radicals in your body. Research has linked oxidative stress to severe neurological diseases, such as Parkinson’s disease, Alzheimer’s disease, multiple sclerosis, and memory loss. [R]
One of the early animal studies on GW501516 investigated its potential effects and found that treated mice had better blood circulation in the brain and reduced oxidative stress. This study shows that Cardarine may protect brain cells against oxidative stress. [R]
Cardarine appears to possess both pro- and anti-inflammatory effects.
In one animal study, Cardarine treatment reduced the presence of TNF-alpha, an inflammatory substance. But in another study, levels of an inflammatory substance (IL-6) increased following GW501516 treatment. High IL-6 has the potential to cause brain cell damage. [R][R]
In a clinical study involving 13 men with high belly fat and a poor cholesterol profile, 2.5 mg Cardarine administration a day for 6 weeks potentially decreased fatty acids, triglycerides, and VLDL proteins. Another study of 12 inactive volunteers found those who took Cardarine had potentially burned more fats. [R][R]
A pre-clinical study has shown that Cardarine may potentially significantly increases fatty acid oxidation and reduces triglyceride amounts. The study further demonstrated that AMPK increases GW501516-dependent expression of a subset of genes involved in fatty acid metabolism. [R]
Cardarine had potentially increased the formation of vascular endothelial growth factor (VEGF) in human heart cells. VEGF is the master regulator of angiogenesis (formation of blood vessels) during growth and development. However, too much VEGF could be problematic for people with cancer. [R]
Low doses of Cardarine significantly reduced atherosclerosis in mice. They did that by repressing monocyte transmigration and inhibiting inflammatory responses evoked by cytokines. These results suggest Cardarine as a therapeutic candidate for atherosclerosis. [R]
In at least three animal and cell-based studies, Cardarine has demonstrated multiple effects that may be beneficial to liver health. Cardarine administration repressed the formation of IL-6 in cells exposed to this compound, thereby potentially preventing/lowering insulin resistance. [R]
A 2015 study linked short-term administration of GW501516 to reduced liver damage in high-fructose-fed mice. In another study, mice exposed to Cardarine treatment were found to be less likely to develop nonalcoholic fatty liver disease. [R][R]
In a mice model of deteriorated kidney function, GW501516 attenuated multiple types of inflammation to boost kidney health. Researchers conducting the study posited that Cardarine may potentially serve as a therapeutic candidate to attenuate specific types of lesions in protein-overload kidney diseases. [R]
Cardarine isn’t a selective androgen receptor modulator. SARMs are small molecule drugs that target androgen receptors in skeletal muscle cells.
In contrast, Cardarine is a PPAR agonist that has shown the ability to improve glucose tolerance and stimulate muscle gene expression, especially those genes involved in preferential lipid utilization.
Cardarine is thought to have a half-life of 12-24 hours.
In a study involving obese monkeys, the group receiving monkeys had higher HDL (‘good’) cholesterol and lower LDL (‘bad’) cholesterol levels at the end of the treatment. [R]
Behemoth Labz is the best place to buy Cardarine GW501516 online.
We have been around since 2014, supplying the highest-quality research compounds money can buy. All of our products come with a 100% satisfaction guarantee, free and fast shipping, and a money-back guarantee. We carry liquid and injectable Cardarine.
Cardarine has demonstrated the potential ability to stimulate fatty acid oxidation in mice fed a high-fat diet. It has also shown potential to improve muscular endurance, increased muscle mass, and caused body fat loss in studies. Behemoth Labz doesn’t sell GW 501516 Cardarine for laboratory research purposes and not for human consumption.
Please make sure you go through the Terms and Conditions, and please familiarize yourself with it as it is important. Please research the scientific uses of this product before making any purchases. Make note that the packaging and labels of the product may differ from those shown on the website.
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ATTENTION: All BehemothLabz products are strictly for LABORATORY AND RESEARCH PURPOSES ONLY. They are not to be used for any human and veterinary purposes.
Keanu Mann –
If you’re looking to lose body far, I will recommend this.
Antoni Jacobson –
You will never go wrong with this Cardarine GW 501516 Liquid. I can recommend this.
Muscle gains, and energy levels throughout the day. I highly recommend it!
I’ve been losing a lot of fat, and I’m performing a lot better, couldn’t ask for better.
Harold Rivera –
Eat healthy with this, and you’ll get the results that you are looking for.
Garret Sawayn –
I’m a repeat buyer of this product. I’m glad that you always have in stock. 🙂 It’s really superb.
Mark Hughes –
Halle Connelly –
You always give me advance notice of when my products will be arriving. Excellent products.
L. Wilkins –
Very good quality, this has really been helping me get rid of my stubborn fat.
E Diaz –
I can honestly say that my belly fat is definitely decreasing.
Mariano Abernathy –
So far I feel like it’s doing the job. I feel stronger at the gym. My arms and chest are looking defined, too.
This has really helped me cut down my fat percentage, I am very impressed with the results I have seen.
Olen Daniels –
Since I started using Cardarine liquid two months ago, my body has seen significant changes. Throughout workouts, I was able to lose weight and felt more energized.