It is well known that exercise is a novel therapy to treat and reduce the incidence of metabolic diseases. Interestingly, PPAR agonists have been studied extensively as potential “exercise-mimetics”, which could be potential therapies for metabolic diseases.
This has lea to numerous studies with GW 0742 in this respective field. A 2019 study investigated whether PPARβ/δ agonist treatment could potentially improve the immune-metabolic changes commonly induced by exercise (such as boosting metabolism) in diet-induced obese mice. Results demonstrated an increase in AMPK activity and fatty acids oxidation gene expression. This may lead to increases in oxidative capacity. [R]
These effects were associated with a decreased in adipose tissue mass, meaning it could potentially burn fat.
GW 0742 May Effect Insulin Resistance
Insulin resistance is when cells in muscles, fat, and liver don’t respond well to insulin and as a result, struggles to take up glucose from blood. As a result, the pancreas needs to produce more insulin to aid glucose transport or glucose metabolism into cells. [R]
This increased production of insulin may lead to co-morbidities such as high blood pressure, cholesterol, and higher triglyceride levels. [R]
Research on insulin resistance in skeletal muscle in mice on a high-fed fructose corn syrup diet showed GW 0742 to ameliorate metabolic abnormalities, including insulin resistance. However, the influence of GW 0742 on systemic insulin sensitivity still warrants further investigation. [R]
GW 0742 May Potentially Improve Lipid Profile
In vivo and vitro studies have shown promising data where PPAR agonists had the potential to improve lipid metabolism in the heart. This will translate to a healthier lipid profile. [R]
A healthy lipid profile is essential for preventing and managing cardiovascular disease, especially with at-risk individuals. However, more clinical studies are required to evaluate the efficacy and safety of GW 0742.
GW 0742 May Have Anti Diabetic Properties
A 2015 study found that GW 0742 reduced hyperglycaemia in type 1 diabetes mellitus rats that had a lack of insulin. [R]
Therefore GW 0742 may potentially be of interest in the future development of anti-diabetic compounds.
GW 0742 May Aid Hypertension Treatment
A 2011 study demonstrated that PPARβ stimulation has the potential ability to reduce blood pressure in hypertensive rats.
The study suggests this could be as a result of the chronic treatment with GW0742 that may reduce vascular remodeling in mesenteric arteries. [R]
GW 0742 FAQs
What is the difference between GW 0742 and Cardarine?
GW 0742 and Cardarine are very similar in that both are PPAR agonists. However, GW 0742 consists of four fluoride and two hydrogen atoms, whereas Cardarine has one hydrogen and two fluoride atoms. This also explains the slightly higher molar mass associated with GW 0742. [R]
GW 0742 is believed to have a higher bio-availability, however more research is required to evaluate these claims.
Is GW0742 Legal?
Yes. GW 0742 is legal to buy and sell as a research chemical. Behemoth Labz sells GW 0742 for laboratory research purpose only.
Can GW0742 cause cancer?
As of the writing of this article, no studies on rats have shown any cancer growth while using GW0742. It is also important to note that these studies were performed in very high doses.
What is the half-life of GW 0742?
It is believed to be similar to Cardarine, between 12 to 24 hours.
Where to buy GW 0742?
Behemoth Labz is the best place to buy GW 0742 online.
We have been around since 2014, supplying the highest-quality research compounds money can buy. All of our products come with a 100% satisfaction guarantee, free shipping, and a money-back guarantee.
GW 0742 is a PPAR receptor agonist with the potential to aid insulin resistance, improve lipid profile, accelerate fat loss, aid hypertension and potentially have anti-diabetic properties.
However, the absence of human studies warrants further investigation into GW 0742 as a chemical compound.
Please make sure you go through the Terms and Conditions, and please familiarize yourself with it as it is important. Please research the scientific uses of this product before making any purchases. Make note that the packaging and labels of the product may differ from those shown on the website.
Buying the product means you agree with our Terms and Conditions. You can contact our awesome customer service team at [email protected] if you are not fully satisfied with the product. Customer satisfaction is our number one priority!
ATTENTION: All BehemothLabz products are strictly for LABORATORY AND RESEARCH PURPOSES ONLY. They are not to be used for any human or veterinary purposes.