Ostarine, a non-steroidal SARM that is orally bioavailable, was originally developed to potentially treat muscle wasting and osteoporosis. Clinical trials have indicated that it has the potential to increase lean body mass in both healthy individuals and cancer patients. [R][R]
Additionally, Ostarine may potentially benefit individuals with heart disease. A clinical trial with 120 healthy older adults found that MK-2866 may potentially lower glycerides, total cholesterol, and LDL cholesterol, which are important markers in preventing heart disease. [R]
Moreover, Ostarine has been suggested to have potentially positive effects on blood glucose levels and insulin resistance. It may also potentially reduce insulin levels in the bloodstream, with effects similar to standard anti-diabetic compounds like metformin.
Animal studies have also highlighted Ostarine’s potential positive effects on bone health, including increased bone strength, mineral and volume density, and faster bone healing. At least two pre-clinical studies have shown these effects. [R]
Arimistane (Androsta-3,5-diene-7,17-dione) (3-deoxy-7-oxo-DHEA) is a metabolite of 7-Keto DHEA that doesn’t convert to estrogen or testosterone. Instead, Arimistane works as an aromatase inhibitor, permanently binding to aromatase enzymes and serving as an estrogen blocker, much like the compound Aromasin.
In addition to reducing estrogen levels, Arimistane has been shown to potentially decrease cortisol, enhance luteinizing hormone (LH), and boost testosterone levels. It works by inhibiting the aromatase enzyme, which reduces the number of androgens that can be converted to estrogen.
Due to its potential for increasing muscle development, some researchers purchase Arimistane for its purported muscle enhancement. However, it is important to note that Arimistane is still considered an experimental compound and should not be consumed by humans.
BehemothLabz offers Arimistane capsules for research purposes only.
Andarine is classified as a selective androgen receptor modulator (SARM) and is currently being researched for its potential to treat muscle wasting and osteoporosis.
Although some SARM companies have included Andarine in bodybuilding products, the FDA considers Andarine unsafe for human consumption.
Andarine has shown promising results in animal studies, with high oral bioavailability, increased lean muscle mass, and improved bone density. [R] Phase I human trials for this SARM were reportedly successful, but no research has been published yet. However, the development of Andarine was halted due to the emergence of Ostarine, another SARM with a similar structure, also known as S-22.
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