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SARMs, or selective androgen receptor modulators, are compounds that may have the potential to help build muscle mass and reduce body fat. They are being researched for the potential to produce similar effects to anabolic steroids but have reduced androgenic properties, which means their side effects will be less intense.
SARMs were originally developed to treat and manage musculoskeletal diseases such as muscle wasting and osteoporosis. Once it became known that they consist of the potential to build lean muscle mass and shred body fat, SARMs became the favorite subject of researchers and scientists.
Ostarine, also known as MK 2866, is a selective androgen receptor modulator or SARM that works by targeting androgen receptors on a selective basis. Ostarine was initially developed as a potential treatment aid for conditions relating to muscle wasting.
Ostarine is known to attach itself to the proteins called androgen receptors. Once it has bound itself, it further denotes these receptors to induce muscular growth. The process for accentuating muscle growth is by altering the genes, which further enhances protein synthesis, complementing muscle growth. [R]
However, more research is required to verify the safety and efficacy of Ostarine and as such the compound is not sold for human consumption and is for research purposes only.
A double-blind placebo-controlled trial set out to investigate the effects of Ostarine on lean body mass and physical function in healthy elderly men and postmenopausal women. It was found that Ostarine produced a dose-dependent improvement in total lean body mass and physical function. [R]
In another trial, Ostarine was studied for its effects on muscle wasting and physical function in patients with cancer. One group was administered a placebo and two groups were given Ostarine. Both MK-2866 groups experienced significant increases in total lean body mass compared to baseline levels. [R]
This shows the massive potential research implications of anabolic effects MK-2866 can possess.
Ostarine has long been researched for its potential ability to improve and increase bone density. In a rat model of osteoporosis, MK-2866 was administered for 5 weeks to ovariectomized rats. Another ovariectomized group of rats received a placebo dose. Final analysis showed improvements in structural properties such as bone mineral density and bone volume density in the Ostarine group. [R]
A recent study investigated the effects of Ostarine administration on fat mass in healthy elderly men and postmenopausal women were noted. A statistically significant decrease in total fat mass was observed at the 3-mg Ostarine dosage [R]
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10ml / 64mg per ml / 640mg
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