Mitragynine Content Grade A+ of over 2%.
White Royal Borneo Kratom Capsules are offered as 120 capsules, totaling 120g.
Kratom leaves come in various colors, which depend on the age of the plant and the strain. The drying and processing methods may also impact the color, but the age of the leaves during harvesting is the most significant factor.
White vein kratom comes from the youngest plant, green vein kratom from a slightly more mature plant, and red vein kratom from a fully mature plant. As the plant matures, different levels of stimulant alkaloids develop in its leaves. These alkaloids determine the effects of the kratom and also give the veins their unique characteristics.
White Royal Borneo is a traditional herb collected from the larger island of Borneo. It is named after the white vein that runs down the middle of the inside of the leaf. White Borneo Kratom is currently being researched for its potential benefits and is mostly recognized for its similarities to coffee.
Further research on White Borneo Kratom could support its use in improving concentration, endurance, relaxation, performance, and various other qualities.
White Borneo Kratom is a type of kratom that comes from the leaves of the Mitragyna Speciosa tree, an evergreen tree in the coffee (Rubiaceae) family that is native to Southeast Asia. It is primarily grown on the island of Borneo, hence its name. [R]
Kratom leaves can vary in color depending on the plant’s maturity and strain. Generally, there are three main colors of kratom: red, green, and white. Red kratom is made from mature leaves and is known for its pain-relieving and relaxing effects. Green kratom is made from slightly less mature leaves than red kratom and is believed to have a balanced energizing and relaxing effect. This makes it a popular choice for researchers exploring pain management and productivity without excessive stimulation or sedation. White kratom is made from the youngest leaves and is known for its energizing effects. Researchers use it to study improvements in focus, motivation, and productivity. [R]
Kratom is a plant that contains around 45 alkaloids, including mitragynine, 7-hydroxymitragynine, paynantheine, speciociliatine, and speciogynine. [R]
The levels of these alkaloids may vary based on the specific kratom strain and how it is grown and processed. Mitragynine is the most abundant alkaloid in kratom and is responsible for many of its effects. It interacts with various brain receptors, including mu-opioid, delta-opioid, and adenosine receptors, and has both stimulating and analgesic properties. 7-hydroxymitragynine, which is considered to be more potent than mitragynine, has similar effects on the brain’s opioid receptors and also acts on serotonin receptors.
Paynantheine has potential anti-inflammatory and muscle-relaxing effects. Speciociliatine is structurally similar to mitragynine but has less potent effects, while speciogynine has mild pain-relieving and calming effects. Additionally, white kratom may contain corynantheidine, mitraphylline, and raubasine, but their exact composition depends on the strain and processing method of the plant. [R]
The effects of White Borneo Kratom can be dose-dependent, as lower doses tend to produce stimulating effects while higher doses may result in sedation. The primary alkaloids found in kratom, mitragynine, and 7-hydroxymitragynine, are well-known and studied for their partial agonist activity at the μ-opioid receptor and competitive antagonist activity at the δ-opioid receptor. These alkaloids share some similarities with traditional opioids but also have some differences. [R]
Opioid receptors are specialized receptors found in the brain and body that opioids bind to in order to produce their effects. These receptors come in different forms, including mu, delta, and kappa receptors, and are responsible for producing pain relief, sedation, and feelings of pleasure or euphoria when activated. Opioids work by mimicking endorphins and other naturally occurring substances in the body that help reduce pain. They increase the brain’s production of these chemicals, which in turn lessens the feeling of pain. However, opioids also affect other bodily systems, such as the digestive and respiratory systems, and often result in euphoria or relaxation in addition to pain relief, which can lead to misuse.
In addition to their interaction with opioid receptors, mitragynine, and 7-hydroxymitragynine also affect other receptors in the brain, including serotonin and dopamine receptors. Mitragynine can inhibit COX-2 and block calcium channel while stimulating α2-adrenergic receptors, which can lead to sedation. [R]
When metabolized in the human body, kratom undergoes phase I and phase II mechanisms, with the resulting metabolites excreted in the urine. Research has shown that kratom extracts can inhibit several enzymes involved in drug metabolism, potentially increasing the risk of drug interactions. [R]
Several studies have explored the potential uses of White Borneo Kratom powder. Here are some of the notable findings:
Several studies have investigated the potential of White Borneo Kratom in managing pain. One randomized, placebo-controlled, double-blind study showed that pain tolerance significantly increased one hour after ingesting kratom, but not after consuming placebo drinks. No discomfort or withdrawal symptoms were observed during kratom discontinuation. While these findings suggest that kratom has potential as a pain reliever, further research is required to determine its safety profile. [R]
In another study, the University of Florida examined lyophilized kratom tea (LKT) and found that it produced significant pain-relieving effects in animal models. These effects were shown to originate from interactions with mu-opioid receptors found in cells throughout the central nervous system. [R]
A study conducted to investigate the impact of mitragynine and a methanolic extract of kratom leaves on the neuromuscular junction and compound nerve action potential found that both the kratom extract and mitragynine had a muscle-relaxing effect by decreasing muscle twitch.
The study also found that the muscle relaxation caused by kratom extract was greater than that of mitragynine. Moreover, high concentrations of both kratom extract and mitragynine blocked nerve conduction, amplitude, and duration of compound nerve action potential. The study suggested that kratom extract may not act as a competitive antagonist of acetylcholine, and its dominant effect may be at the neuromuscular junction. Further research is needed to explore the safety and efficacy of kratom extract as a muscle relaxant. [R]
A study was conducted to investigate the potential anti-inflammatory and antinociceptive properties of the methanol extract of Mitragyna speciosa, specifically in rodents. The extract was subjected to various tests, including the writhing test, hot plate test, and formalin test in mice and rats, as well as the carrageenan-induced paw edema and cotton pellet-induced granuloma tests in rats.
The findings indicated that the extract displayed significant dose-dependent activity in all nociceptive models tested, and effectively reduced the development of carrageenan-induced rat paw edema. The results support the traditional use of the extract as an agent with potent antinociceptive and anti-inflammatory properties. [R]
According to a survey conducted on 2,798 test subjects, 67% reported using Kratom primarily for anxiety. [R]
Additionally, a case study details the experience of a 63-year-old who had been using Kratom for 7 years to manage chronic major depression and anxiety disorder. However, with the onset of the COVID-19 pandemic and heightened work-related stress, the usual Kratom dosage failed to alleviate the patient’s symptoms. Consequently, the patient sought treatment, and after being detoxified from Kratom, their anxiety and depression management shifted towards medication and psychotherapy. [R]
A study investigated the potential antidepressant effect of mitragynine, the major active alkaloid found in Mitragyna speciosa leaves, using predictive models of antidepressant activity in mice, namely the forced swim test (FST) and tail suspension test (TST). The study also assessed the impact of mitragynine on the hypothalamic-pituitary-adrenal (HPA) axis, a key neuroendocrine system involved in stress response, by measuring the corticosterone levels in mice exposed to FST and TST.
The findings suggest that mitragynine may have an antidepressant effect on animal behavioral models of depression by interacting with the HPA axis. However, more research is needed to understand the precise mechanism of action of mitragynine and its potential use in treating depression. [R]
In addition to a lack of consistent evidence of direct benefits, the potential long-term effects of using White Borneo Kratom daily are also unknown. Behemothlabz sells White Borneo Kratom for research purposes only.
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120 capsules / 120g
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