Buy Ipamorelin for Sale – Product Details
Ipamorelin is a synthetic peptide that can stimulate growth hormone release from the pituitary gland. Preclinical studies have shown that it can induce weight gain, increase bone mineral density, and evoke a significant increase in insulin secretion from the pancreas.
Ipamorelin has also demonstrated the ability to counteract the reduction in muscle strength and bone formation in glucocorticoid-injected rats. All these effects were observed in animal studies. Ipamorelin is yet to undergo any randomized, placebo-controlled trials.
- CAS Number is stated as 170851-70-4
- Molar Mass is 711,868g·mol−1
- It has a Chemical Formula as C38H49N9O5
- IUPAC Name: (2S)-6-Amino-2-[[(2R)-2-[[(2R)-2-[[(2S)-2-[(2-amino-2-methylpropanoyl)amino]-3-(4H-imidazol-4-yl)propanoyl]amino]-3-naphthalen-2-ylpropanoyl]amino]-3-phenylpropanoyl]amino]hexanamide
- Also known by Synonyms as UNII-Y9M3S784Z6
Behemoth Labz sells Ipamorelin for laboratory and research use only.
What is Ipamorelin?
Ipamorelin is a synthetic pentapeptide (made up of a chain of five amino acids). It stimulates growth hormone (GH) secretion and is thus known as a GH. Research has shown that its selectivity for GH is similar to that of GH-releasing hormone (GHRH), a natural hormone. [R]
Ipamorelin is also referred to as a ghrelin mimetic because it mimics the action of ghrelin in the body. Ghrelin is a gut hormone that regulates hunger and stimulates GH release. Besides Ipamorelin, other ghrelin mimetics include MK-677 (Ibutamoren) and Hexarelin. [R]
Similar to other ghrelin mimetics, Ipamorelin induces GH release without affecting thyroid-stimulating hormone, follicle-stimulating hormone (FSH), or luteinizing hormone (LH). Its potency and efficacy to release GH are similar to that of GH-releasing peptide 6 (GHRP-6). [R]
However, Ipamorelin is different from other GH secretagogues on one count. It releases GH without significantly affecting plasma ACTH (adrenocorticotropic hormone) or cortisol. Researchers believe this makes it an interesting candidate for future clinical development. [R]
How does Ipamorelin Work?
Ipamorelin induces the release of GH by mimicking the actions of ghrelin. It binds to the ghrelin receptor (GH secretagogue receptor or GHSR) in the hypothalamus to selectively stimulate the release of growth hormone from the anterior pituitary gland. [R][R]
Adequate GH release is crucial for our health. That is because growth hormone influences height, builds bones and muscles, and regulates metabolism. GH deficiency in adults leads to reduced muscle mass, increased fat, and impaired quality of life. [R]
A summary of the existing research on this selective growth hormone secretagogue follows. The information presented in this section is for educational purposes only. Behemoth Labz doesn’t sell Ipamorelin for veterinary or human consumption.
1) Ipamorelin and Bone Health
According to a preclinical study, Ipamorelin and GHRP-6 increased bone mineral content (BMC) in adult female rats. The animals treated with both research chemicals experienced increased total tibial and vertebral BMC. Their body weights also increased. [R]
Another study reports that Ipamorelin dose-dependently increased the longitudinal bone growth rate (LGR) in adult female rats. The highest dose group experienced a 24% increase in LGR. [R]
2) Ipamorelin and Weight Gain
An animal study investigated the effects of Ipamorelin and GH on the body fat of GH-deficient mice. Results from the study show that Ipamorelin increased body fat. Interestingly, the mechanisms by which it did that were GH-independent and may include increased food intake. [R]
Researchers then administered Ipamorelin to normal rats to investigate whether the above effect was limited to GH-deficient rats. After only two weeks of treatment, Ipamorelin-treated mice showed an overall increase in body weight compared to baseline values. [R]
3) Ipamorelin and Negative Corticosteroid Effects
Glucocorticoids (also known as corticosteroids) are naturally occurring steroids. They have anti-inflammatory properties and are clinically used to treat inflammation-related conditions. However, patients treated with GCs may experience muscle weakness or water retention. [R]
In an in vivo adult rate model, Ipamorelin treatment counteracted the decrease in muscle strength brought about by prior injections of glucocorticoids. [R]
4) Ipamorelin and Diabetes
In a preclinical study involving diabetic mice, Ipamorelin evoked significant increases in insulin secretion from the pancreas of the animals. The same effect was observed when Ipamorelin peptide was administered to normal mice. [R]
Ipamorelin’s above effect was most likely a result of this synthetic peptide indirectly stimulating the calcium channel on the pancreatic islet cells, where insulin is produced and kept. [R]
5) Ipamorelin and Post-Operative Ileus
Post-operative ileus is a condition in which the bowel stops functioning after surgery. Symptoms include nausea, constipation, vomiting, and stomach cramps. While it’s mostly not deadly, post-operative ileus may become fatal if prolonged and untreated. [R]
Ipamorelin has undergone phase 2 trials as a potential treatment for post-operative ileus. Those trials showed that Ipamorelin reduced the time to the first meal by half a day. Unfortunately, the trials were abandoned after indicating due to lack of efficacy. [R]
Frequently Asked Questions
Does Ipamorelin help with muscle growth?
At the time of writing, no study has demonstrated Ipamorelin’s ability to stimulate muscle growth. Thus, it can be safely said that more research is needed.
What is the half-life of Ipamorelin?
Ipamorelin has a relatively short half-life of 2 hours. [R]
Where to Buy Ipamorelin for Sale?
Behemoth Labz is the best place to buy Ipamorelin online.
We have been around since 2014, supplying the highest-quality research chemicals money can buy. All of our products come with a 100% satisfaction guarantee, free and fast shipping, and a money-back guarantee on Ipamorelin.
Ipamorelin is a synthetic peptide that stimulates growth hormone release in the body. Preclinical studies show that it can improve bone formation and strength, increase insulin release, and counteract the adverse effects of corticosteroids. However, no clinical trials have explored its safety or efficacy yet.
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