Level Up Combo (LGD-4033 + MK-677 + 4-Andro + YK-11) – Product Details

LGD-4033

Ligandrol, also known as LGD-4033, belongs to a class of non-steroidal compounds known as selective androgen receptor modulators (SARMs). SARMs are unique small-molecule compounds that exhibit a specific affinity for androgen receptors. By selectively targeting these receptors, SARMs possess the potential ability to stimulate anabolic activity within cells, promoting muscle growth, without the unwanted side effects associated with traditional anabolic compounds.

Initially, Ligandrol was developed with the aim of addressing muscle-wasting conditions. In its first clinical trial, this remarkable compound demonstrated its potential by increasing muscle mass without causing a concurrent increase in fat mass. Moreover, it was found to regulate levels of total testosterone, triglycerides, and high-density lipoprotein cholesterol in participants, suggesting its potential therapeutic applications. [R]

Further studies in a phase 2 clinical trial explored the effects of Ligandrol on patients recovering from a hip fracture. Encouragingly, it was observed that Ligandrol administration led to a dose-dependent increase in walking distance, indicating its potential role in improving mobility and facilitating recovery. Additionally, compared to a placebo, LGD-4033 exhibited significant dose-dependent increases in lean body mass, further highlighting its ability to enhance muscle development. [R]

In an experimental rat model where ovariectomy was performed, Ligandrol treatment displayed notable benefits. The animals treated with Ligandrol exhibited improved muscle tissue, increased muscle weight, and higher intramuscular fat content. These findings suggest that Ligandrol may have positive effects on muscle health and composition, making it an intriguing area for further exploration.

The research conducted on Ligandrol underscores its potential as a valuable compound in addressing muscle wasting conditions and promoting muscle growth. However, it is important to note that Ligandrol is still under investigation, and its use should be limited to scientific research purposes.

MK-677

MK 677, also known as Ibutamoren, is an orally active compound classified as a growth hormone secretagogue. Its unique mechanism of action stimulates the release of growth hormone (GH) from the pituitary cells. Studies have consistently demonstrated the ability of MK 677 to elicit greater GH responses compared to standard GH secretagogues, making it an intriguing area of research in the field.

In addition to its effects on GH release, Ibutamoren has been shown to increase levels of insulin-like growth factor 1 (IGF-1). Animal studies have revealed that repeated administrations of MK 677 result in sustained elevation of IGF-1 levels. This effect has also been observed in various clinical trials, further supporting the notion that MK 677 can effectively enhance IGF-1 levels. [R]

Furthermore, MK 677 has been found to elevate concentrations of insulin-like growth factor binding protein 3 (IGFBP-3) in healthy older adults and individuals with GH deficiency. Alongside these findings, clinical studies have highlighted the positive impact of this growth hormone secretagogue on body composition and metabolism in older adults. These observations suggest that MK 677 holds promise as a potential therapeutic option for improving overall body composition and metabolic function. [R]

The research conducted on MK 677 underscores its ability to stimulate GH release, increase IGF-1 levels, and enhance body composition and metabolism. However, it is important to note that MK 677 is currently under investigation and should only be used for research purposes under appropriate guidance. [R]

 4-Andro

4 Andro, also referred to as 4-DHEA or 4-Androstenediol, is a member of the prohormone class of compounds. Prohormones are unique chemicals that undergo conversion to form anabolic hormones. These anabolic hormones play a vital role in stimulating protein synthesis and promoting muscle growth. [R]

One noteworthy aspect of 4 Andro is its status as a metabolite of DHEA, a natural hormone utilized by the body to synthesize both male and female sex hormones. In particular, 4 Andro is treated as a precursor of testosterone, indicating that this novel prohormone is utilized to support the production of the male sex hormone. [R] [R]

The positive impact of 4 Andro on testosterone levels has been demonstrated in various animal studies, showcasing its ability to enhance skeletal muscle growth. Importantly, despite the elevation in testosterone levels and the promotion of muscle growth, 4 Andro has not shown any adverse effects on sexual organs. [R]

The research surrounding 4 Andro sheds light on its potential as a prohormone that can positively influence testosterone levels and facilitate muscle growth. These findings contribute to a better understanding of its role in the body’s hormonal processes and its potential applications in the field of muscle development. However, it is important to note that 4 Andro is a research chemical and should only be used for scientific purposes under appropriate guidance.

YK-11

YK 11, classified as a selective androgen receptor modulator (SARM), possesses the unique characteristic of also functioning as a myostatin inhibitor. Scientific investigations have revealed that the chemical structure of YK 11 closely resembles that of dihydrotestosterone (DHT). DHT, known for its increased potency compared to testosterone, interacts with androgen receptors in various areas such as the prostate, sex organs, hair, and liver.

In contrast to many SARMs that act as full agonists of the androgen receptor (AR), YK 11 demonstrates the potential to only partially activate this receptor. This sets it apart from popular SARMs. Additionally, YK 11 exhibits the ability to inhibit myostatin.

It is important to note that most SARMs do not appear to have any significant impact on myostatin production. This distinction emphasizes the unique nature of YK 11 as a compound that potentially offers a dual mechanism of action, influencing the androgen receptor and inhibiting myostatin production. [R]

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