The liquid OTR-AC for sale from Behemoth Labz is for laboratory research use only and is not for human consumption. Otherwise known as Ostarine O Acetate, this SARM has undergone esterification during chemical synthesis, which makes it bioactive for ten times longer.
Preclinical research suggests that this leads to more stable blood levels and makes clinical research on lab rats and animals far easier. It requires decreased dosing frequency due to its longer half-life compared to any other selective androgen receptor modulator.
Despite the potential to remain bioactive ten times longer than most universally suitable SARMs and other anabolic agents, OTR AC MK 2866 is one of the least researched SARMs.
The AC MK 2866 ester is often researched alongside these compounds due to the potential chemical synthesis they have together, although again, more research is required.
CAS Number is stated as 1025658-44-9
Molar Mass is 431.37 g/mol
It has a Chemical Formula of C21H16F3N3O4
IUPAC Name is 5-(1H-pyrazol-5-yl)-1-[2-[4-(trifluoromethoxy)phenoxy]ethyl]indole-2-carboxylic acid
The Ligandrol for sale from Behemoth Labz is 3rd party tested for the utmost purity.
What is OTR-AC – Selective Androgen Receptor Modulator?
Ostarine is one of the selective androgen receptor modulators. It is a chemical that has a structure known as aryl-propionamide, and it is categorized as a non-steroidal compound since it does not undergo the standard steroid transformations of aromatization and reduction by 5 reductase. In other words, it does not have an aryl-propionamide structure.[R]
Although ostarine is used for improving athletic performance, involuntary weight loss due to illness, breast cancer, and a wide variety of other conditions, there is insufficient evidence to support these uses from a scientific standpoint.
How does OTR-AC Work?
In contrast to testosterone and other non-selective synthetic anabolic steroids, selective androgen receptor modulators are a new class of non-steroidal, tissue-specific anabolic agents currently being researched for its potential to increase muscle mass and improve physical function. To selectively alter the androgen receptor’s ability to regulate gene expression, Ostarine potentially binds to the receptor and causes conformational changes. These changes may affect the receptor’s interaction with co-activator and co-repressor proteins in different tissues.
OTR-AC, a research chemical, has undergone various animal and cell-based studies, as well as clinical research, which has indicated its potential to increase muscle growth, promote bone healing, and treat endometriosis.
Despite these promising findings, the FDA has not yet approved OTR-AC for human consumption due to the lack of large-scale, randomized, and placebo-controlled trials. Therefore, BehemothLabz offers OTR-AC for laboratory and research purposes only and not for human use.
OTR-AC and Bone Healing
In a study investigating the potential benefits of ostarine on bone healing in ovariectomized rats. The study found that ostarine, especially at a dose of 4mg/kg body weight, improved callus formation, increased callus density, sped up the time it took for the osteotomy to heal, and increased alkaline phosphatase gene expression in the callus and its protein expression in the serum. This showed that ostarine helped ovariectomized rats’ early bone healing.[R]
Nevertheless, potential metabolic side effects of ostarine need to be thoroughly evaluated through preclinical research prior to considering it as a therapy for osteoporosis.
OTR-AC and Muscle Mass/Muscle growth
Cancer patients often lose muscle fibers(muscle wasting), which can lower their quality of life and make them more likely to die. In a study of women who had gone through menopause and men over 45 with stage III or stage IV NSCLC, Ostarine was shown to work by targeting androgen receptors in the body. This can help stop muscle loss and promote muscle building. At the moment, the drug is being tested in two Phase 3 clinical trials to see how well it prevents and treats muscle loss in chemotherapy patients with non-small-cell lung cancer. The administration of GTx-024 led to dose-dependent increases in total lean muscle mass (lean body mass) that were statistically significant and meaningful from a clinical perspective. [R]
More research should be done to understand the potential chemical synthesis and effect of OTR AC on lean muscle mass and body fat.
OTR-AC and Endometriosis
Ostarine is being examined for its ability to cure endometriosis in women within the realm of medical research. Prior to moving on with clinical trials, it is necessary to continue researching any potential hazards, despite the fact that earlier research has found no significant side effects of the drug in women. Intriguingly, investigations on mice indicate that GTx-024 therapy can raise uterine weight, but only to the level found in healthy animals. This indicates that the medicine may be a safe and beneficial alternative for endometriosis patients. [R]
However, additional research is required to confirm these findings and assure the compound’s safety for human consumption.
OTR-AC and Sarcopenia
Resistance training and dietary counseling are examples of non-pharmacological approaches that can be used to reduce sarcopenia in patients undergoing chemotherapy. Other supplements such as vitamin D require replacement in the event that it has been depleted, the use of omega-3 fatty acids, testosterone, selective androgen receptor modulators (SARMS), and ghrelin are all examples of pharmacologic therapies. [R]
SARMs, which stand for selective androgen receptor modulators, have the potential to increase lean body mass (LBM), and consequently muscle mass, without the adverse side effects that are typically associated with conventional anabolic agents. Data suggest that using enobosarm could increase lean body mass without the harmful side effects of androgens and progestational agents. There were 100 people in the evaluable efficacy population. Compared to the start of the study, both enobosarm groups had significant increases in total lean body mass by day 113 or the end of the study. The placebo group’s total lean body mass didn’t change much. [R]
The use of selective androgen receptor modulators (SARMs) or any other supplementation for the treatment of Sarcopenia needs more human studies to understand how it will stop weight loss in cancer patients.
OTR-AC and Breast cancer
Overexpression of androgen receptor is the defining characteristic of the distinct molecular subtype of triple-negative breast cancer (TNBC) known as Luminal Androgen Receptor Breast Cancer (AR). In patients with AR-positive (AR+) TNBC, AR-targeted therapy has demonstrated some level of activity. Enobosarm, also known as GTx-024, is a nonsteroidal selective androgen receptor modulator (SARM) that has shown activity in both preclinical studies and clinical studies involving AR+ breast cancer.
Enobosarm and pembrolizumab in combination were well tolerated, with a modest clinical benefit rate of 25% at 16 weeks in heavily pretreated AR+ TNBC patients who did not have preselected programmed death ligand [R]
OTR-AC Side Effects
Ostarine presents a potential health risk when consumed orally. It is possible that it will damage the liver in addition to causing other serious side effects such as a heart attack. [R]
Frequently Asked Questions (FAQs)
What is the half-life of OTR-AC?
Because esterification of anabolic agents results in a minimum increase of 10-fold in half-life, this indicates that the active ingredient has the potential to remain bioactive ten times longer than before.
Is OTR-AC legal?
Ostarine is an investigational compound, and the US FDA has not approved it for any use. Despite this, it is occasionally present in dietary supplements, particularly bodybuilding-oriented products. Both the World Anti-Doping Agency (WADA) and the National Collegiate Athletic Association have made it illegal to use ostarine and other SARMs in athletic competitions (NCAA). The Ostarine product we sell is intended for research use only or laboratory research use
Is Ostarine the same as Ostarine O Acetate?
Ostarine is not the same as OTR-AC (Ostarine O Acetate). A selective androgen receptor modulator (SARM) called Ostarine, often referred to as MK-2866, is used to increase bone density and muscle mass. OTR-AC is an altered form of ostarine that has an acetate ester added to it so that the body can absorb it more quickly. OTR-AC, a SARM, is thought to have effects that are comparable to those of Ostarine but may be more strong.
Where to Buy OTR-AC for Sale?
Behemoth Labz is the best sarms supplier to buy sarms such as OTR AC Liquid.
We have been around since 2014, supplying the highest-quality research compounds money can buy. All of our products come with a 100% satisfaction guarantee, free shipping, package fast, professional and discreet packing, great customer service, and a money-back guarantee. We are a great company that carries OTR-AC liquid and produces universally suitable sarms. More sarms available on our website
OTR-AC, also known as Ostarine O Acetate, is a research chemical categorized as a non-steroidal compound that belongs to the selective androgen receptor modulators class. OTR-AC, has indicated its potential positive effect to increase muscle tissue or build muscle mass, promote bone healing, and treat endometriosis. OTR-AC has undergone various animal and cell-based studies, as well as clinical research.
However, the FDA has not approved OTR-AC for human consumption due to the lack of large-scale, randomized, and placebo-controlled trials. Therefore, it is sold by BehemothLabz for laboratory and research purposes only and not for human use. OTR-AC has potential side effects that need to be evaluated thoroughly before considering it as a therapy.
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