Super Lean Stack (MK-2866 + SR-9009 + GW-0742)

Super Lean Stack combines Ostarine (MK-2866), SR9009, and GW0742 to enhance muscle development, endurance, and metabolic function. Ostarine, a selective androgen receptor modulator (SARM), allegedly helps maintain lean muscle mass and may improve bone density. SR9009 might boost endurance by enhancing mitochondrial activity, potentially benefiting physical performance and metabolic regulation. GW0742 acts as a PPARδ agonist, potentially aiding muscle recovery and improving insulin sensitivity. It’s crucial to note that these compounds are intended for research purposes only and have not been approved for human consumption.

Super Lean Stack Product Details

MK-2866

• CAS Number: 841205-47-8
• Molar Mass: 389.334 g·mol−1
• Chemical Formula: C19H14F3N3O3
• IUPAC Name: ((2S)-3-(4-cyanophenoxy)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide)
• Also known by Synonyms as: Enobosarm; GTx-024; MK-2866; Ostarine; S-22

SR9009

• CAS Number is stated as 1379686-30-2
• Molar Mass is 437.94026 g·mol−1
• It has a Chemical Formula of C20H24ClN3O4
• IUPAC Name is ethyl-3-(((4-chlorobenzyl)((5-nitrothiophene-2-yl)methyl)amino)methyl)pyrrolidine-1-carboxylate
• Also known by Synonyms as Stenabolic

GW0742

• CAS Number is stated as 317318-84-6
• Molar Mass is 471.48 g·mol−1
• It has a Chemical Formula of C21H17F4NO3S2
• IUPAC Name is [4-[[[2-[3-fluoro-4-(trifluoromethyl)phenyl]-4-methyl-5-thiazolyl]methyl]thio]-2-methyl phenoxy]-acetic acid
• Also known by Synonyms as GW610742; Acetic acid, 2-[4-[[[2-[3-fluoro-4-(trifluoromethyl)phenyl]-4-methyl-5-thiazolyl]methyl]thio]-2-methylphenoxy]; Acetic acid, [4-[[[2-[3-fluoro-4-(trifluoromethyl)phenyl]-4-methyl-5-thiazolyl]methyl]thio]-2-methylphenoxy]; 2-[4-[[[2-[3-Fluoro-4-(trifluoromethyl)phenyl]-4-methyl-5-thiazolyl]methyl]thio]-2-methylphenoxy]acetic acid; GWδ 0742

What is Super Lean Stack? 

These are the top-notch research compounds in Super Lean Stack Capsules. Per capsule, a combination of:

• MK-2866 20mg
• SR9009 20mg
• GW0742 20mg

Super Lean Stack is offered as 60 mg per capsule for 60 capsules, totaling 3.6g

What is MK-2866? 

Formerly being studied by Merck & Company for the treatment of conditions like muscle wasting and osteoporosis is the investigational selective androgen receptor modulator (SARM) ostarine, also known as enobosarm or MK-2866. [R]

Selective androgen receptor modulators (SARMs) have a tissue-specific activation of androgenic signaling when they bind to androgen receptors. [R]

In a few tests on test subjects, it was discovered that Ostarine had potential anabolic effects on bone and muscle, both independently and together. [R]

Since no SARM has achieved clinical approval, little is known about the advantages and disadvantages that participants may experience. [R]

Behemoth Labz sells MK-2866 for laboratory research use only.

We also carry Ostarine – Liquid and OTR-AC (Ostarine O-Acetate) (Liquid)  if you’re looking for those instead. 

What is SR9009? 

Professor Thomas Burris of the Scripps Research Institute created the research compound SR9009, also known as Stenabolic, as an agonist of Rev-ErbA (i.e., it promotes the constitutive repression of genes controlled by Rev-ErbA). [R] REV-ERB is recognized as a circadian clock and cell metabolism integrator. [R]

SR9009 was added to the World Anti-Doping Agency’s list of prohibited substances. [R] This research compound is not approved by the FDA for medical use. [R] 

Behemoth Labz sells SR9009 for laboratory research use only.

We also carry SR9009 Stenabolic Capsules, SR9009 Stenabolic Liquid, SR9009 Transdermal, and SR9009 Parenteral Solution if you’re looking for those instead. 

What is GW0742?

Nuclear receptors of the PPAR-beta (peroxisome proliferator-activated receptor beta) subclass are involved in the modulation of inflammation and lipid metabolism. It is expressed in various tissues, including adipose tissue, liver, heart, and skeletal muscle. It is generally known that PPAR-beta affects glucose metabolism and energy homeostasis. [R] In this case, GW0742 is a known PPARbeta agonist. [R] 

Given that it has been found to improve mitochondrial biogenesis and endurance capacity in animal models, PPAR-beta has also been explored as a viable target for increasing athletic performance. [R]

Behemoth Labz sells GW0742 for laboratory research use only.

We also carry GW0742 Capsules and GW0742 Liquids if you want those instead.

Potential Applications of Super Lean Stack (Ostarine (MK-2866) + SR9009 + GW0742)

Potential Increase in Muscle Mass

Ostarine, also known as MK-2866, is under investigation for its ability to counteract muscle wasting in various groups, including test subjects with cancer, participants with muscular dystrophy, and elderly test subjects. 

Research has highlighted the muscle-enhancing potential of Ostarine. In a trial with 120 healthy older adult test subjects, those who took Ostarine daily for 12 weeks showed a potential increase in lean muscle mass and improved physical fitness. The side effects observed were comparable to those in the placebo group, suggesting a solid safety profile. [R]

A study with 159 cancer test subjects indicated that Ostarine could help increase lean muscle mass, especially in those experiencing muscle loss. Participants in this study gained about 2-3 pounds of muscle over roughly four months of treatment. [R]

Ongoing, larger-scale clinical trials aim to explore further Ostarine’s effectiveness in preventing muscle loss in test subjects with cancer.

Potential Bone Health

Ostarine, a Selective Androgen Receptor Modulator (SARM), shows promise for improving bone health, particularly in older adult test subjects. By mimicking testosterone, Ostarine targets androgen receptors in muscles and bones, promoting a potential increase in muscle mass and bone strength. Enhanced muscle mass supports better bone stability and reduces fracture risks, which is crucial for aging test subjects. [R][R]

Animal studies indicate that SARMs like Ostarine may boost muscle and bone strength, suggesting potential benefits for bone density and overall bone health. This dual action may help prevent osteoporosis and improve mobility and quality of life for older test subjects. [R]

Potential Heart Health Benefits

Ostarine, also known as Osta 2866, could offer heart health benefits, especially for those with heart disease who frequently experience muscle wasting and weight loss. By boosting lean muscle mass, Ostarine may enhance physical function and lessen the burden on the heart. [R]

In a study involving 120 healthy elderly test subjects, using Ostarine for 12 weeks was associated with decreased levels of triglycerides, total cholesterol, and HDL cholesterol. These lipid profile improvements indicate that Ostarine might reduce the risk of cardiovascular incidents. [R]

Potential Insulin Resistance Help

Ostarine, which contains the active compound Enobosarm, appears to improve insulin sensitivity and decrease blood glucose levels. These benefits might aid people with diabetes or metabolic syndrome by promoting more efficient glucose use and lowering blood sugar levels, thus reducing the risk of complications like cardiovascular problems and nerve damage. [R]

Potential Weight Loss Benefits

SR9009, a compound studied primarily in animal models, shows promise for weight loss through various mechanisms. Research indicates significant findings in mice model experiments, where SR9009 administration led to potentially reduced fat mass without affecting food intake. In one study, mice models treated with SR9009 for seven days experienced potential weight loss primarily due to decreased fat accumulation. [R]

Furthermore, in obese mice models, prolonged treatment with SR9009 over 30 days resulted in even more significant weight loss compared to untreated controls, demonstrating potential efficacy in managing obesity. Another study highlighted SR9009’s ability to prevent weight gain in genetically obese mice models within a short timeframe, around 12 days, without impacting glucose or insulin levels. [R]

These findings suggest that SR9009 may aid weight loss by targeting fat mass reduction and potentially improving metabolic markers such as triglycerides, cholesterol, and insulin sensitivity. 

Potential Endurance Benefits

SR9009, based on studies primarily conducted in mice models, shows promising potential for enhancing endurance. Research indicates that after 30 days of treatment, mice models treated with SR9009 demonstrated potentially improved endurance capabilities, running longer and covering greater distances than control groups. [R]

Moreover, SR9009 appears to enhance endurance by potentially increasing the number of total and active mitochondria within muscle cells. This effect is attributed to SR9009’s ability to suppress autophagy genes, which enhances mitochondrial function and energy production. Mitochondria are crucial for producing ATP, the energy currency of cells, thereby supporting prolonged physical performance and endurance. [R]

These findings suggest that SR9009 might significantly improve endurance through enhanced mitochondrial activity and efficiency. 

Potential Help in Wakefulness

SR9009, functioning as an activator of REV-ERB, has shown potential in altering sleep and wake patterns based on studies conducted in mice models. Its effects are short-term, typically lasting approximately 12 hours. [R]

Research indicates injecting SR9009 during the day potentially increases daytime activity levels in mice models. This is accompanied by reduced deep sleep stages, including REM (rapid eye movement) and slow-wave sleep. These changes suggest that SR9009 may promote wakefulness and reduce periods of deep rest during active periods. [R]

Interestingly, injecting SR9009 at night, when mice models are naturally more active, did not produce the same effects on sleep patterns. This indicates that SR9009’s impact on sleep/wake cycles may be influenced by the timing of administration relative to the animal’s circadian rhythm.  [R]

These findings highlight SR9009’s potential role in modulating wakefulness and sleep architecture, though further research is needed to understand its mechanisms, including implications for disorders involving sleep disturbances. [R]

Potential Muscle Regeneration Benefits

GW0742 has demonstrated significant potential in promoting muscle regeneration and enhancing endurance in mouse models. It accelerates skeletal muscle regeneration following injury and potentiates endurance by increasing running parameters in trained mice models. Additionally, it enhances endurance capacity by reducing skeletal muscle inflammation in obese female mice models and induces endurance-like oxidative muscle remodeling. [R][R]

Furthermore, GW0742 potentially increases the formation of new blood vessels and heart muscle mass. These effects are mediated by the activation of PPARβ/δ, which promotes new blood vessel formation and muscle fiber production. These findings suggest that GW0742 could have therapeutic applications in enhancing muscle recovery and endurance. [R][R]

Potential Brain Cognition Effects

GW0742 exhibits significant potential in enhancing brain cognition and safeguarding against cognitive dysfunction across various animal models. Research indicates that GW0742 may mitigate cognitive impairment induced by radiation, decrease brain toxicity from beta amyloids, and play an essential role in the maturation of brain cells. In Alzheimer’s disease models, potential benefits have been shown by ameliorating deficits via increased fatty acid oxidation in astrocytes and reducing abnormal brain proteins and proinflammatory markers. In Parkinson’s disease models, GW0742 parenteral solutions offer neuroprotective effects and avert cognitive decline. [R][R]

Additionally, GW0742 potentially prevents spatial memory deficits in diabetic mice models and reduces cognitive impairment linked to insulin resistance and high sugar intake in rat models. It has also demonstrated neuroprotective properties in global cerebral ischemia-reperfusion injury cases and decreased cell death during low-KCl media exposure. These findings suggest that GW0742 has broad potential for enhancing cognitive function and protecting against brain dysfunction. It is a promising therapeutic option for neurodegenerative diseases and cognitive impairments associated with metabolic disorders. [R]

Potential Decrease in Blood Sugar Levels

GW0742 shows excellent potential in lowering blood sugar levels and addressing diabetes-related issues, as shown by various studies in animal models. In diabetic mice models, it has been proven to enhance blood sugar balance, positioning it as a promising candidate for future anti-diabetic drugs. In diabetic rat models, daily GW0742 parenteral solutions prevented numerous diabetes complications, while oral administration in diabetic mice models improved memory problems associated with type 2 diabetes. [R]

Additionally, GW0742 induces beneficial vascular changes in diabetic rats, improves blood sugar metabolism, and positively influences gene regulatory responses in obese mice models. Treatment with GW0742 allegedly enhances insulin signaling in rat models and protects against kidney issues and nerve damage in diabetic mice models. These results indicate that GW0742 might be a potential treatment for lowering blood sugar levels and managing diabetes.[R]

How Does Super Lean Stack Work? 

Super Lean Stacks leverages Ostarine, SR9009, and GW0742’s combined benefits to support muscle development, boost endurance, and enhance overall metabolic function. Ostarine, a selective androgen receptor modulator (SARM), potentially aids in building lean muscle mass and improving physical performance. SR9009, a REV-ERB agonist, presumably increases endurance by boosting mitochondrial activity and energy production, potentially assisting with weight loss and sleep regulation. GW0742, a PPARδ agonist, allegedly promotes muscle regeneration, improves insulin sensitivity, lowers blood sugar levels, and offers neuroprotective effects. This powerful combination of compounds is designed to optimize physical performance, aid muscle recovery, and improve metabolic health.

Safety and Side Effects

The safety and potential side effects of Super Lean Stack, which include Ostarine, SR9009, and GW0742, vary depending on each ingredient. Ostarine is generally considered safe when used as recommended but may cause mild effects such as headaches, nausea, and slight testosterone suppression. SR9009 is valued for its positive impact on endurance and metabolism, though its long-term safety remains uncertain, potentially causing issues like sleep disruptions and liver concerns. GW0742, noted for its role in muscle repair and metabolic enhancements, may occasionally result in gastrointestinal problems and could worsen pre-existing liver conditions. Test subjects must approach the Super Lean Stacks cautiously, follow recommended dosages, and seek advice from healthcare professionals to manage risks and monitor for adverse reactions effectively.

Frequently Asked Questions

What is Super Lean Stack?

Super Lean Stack combines research compounds encapsulated for specific benefits. Each capsule contains:

• MK-2866 (Ostarine) 20mg
• SR9009 20mg
• GW0742 20mg

This Stack is formulated to provide 60 capsules, each containing 60 mg of the combined ingredients, totaling 3.6 grams.

What are the potential benefits of studying Ostarine (MK-2866)?

Ostarine, also known as MK-2866, is a selective androgen receptor modulator (SARM) initially studied by Merck & Company for conditions like muscle wasting and osteoporosis. It shows promise in:

• Potentially increasing lean muscle mass and physical performance
• Potentially improving bone health by mimicking testosterone effects on androgen receptors in muscles and bones
• Offering potential benefits for heart health and insulin sensitivity

Although primarily for research purposes, ongoing studies explore its potential therapeutic applications.

What are the potential benefits of studying SR9009?

SR9009, or Stenabolic, is a REV-ERB agonist that influences circadian rhythms and cellular metabolism. Key benefits include:

• Potentially enhancing endurance and physical performance by boosting mitochondrial activity
• Potential assistance in weight management through metabolic enhancement
• Potential regulation of sleep patterns

While primarily used in research, SR9009 shows promise in various preclinical studies.

What are the potential benefits of studying GW0742?

GW0742 is a PPARδ agonist known for its effects on inflammation modulation and lipid metabolism. Benefits include:

• Potentially promoting muscle regeneration and enhancing endurance capacity
• Potential improvements in insulin sensitivity and blood sugar levels
• Potential neuroprotective effects in models of neurodegenerative diseases

Summary

Super Lean Stack utilizes the combined potential of MK-2866 (Ostarine), SR9009, and GW0742 to provide a comprehensive strategy for potential muscle growth, enhanced endurance, and metabolic support. MK-2866 demonstrates the potential to counteract muscle loss and enhance bone health. SR9009 complements this by potentially improving endurance through increased mitochondrial activity and potential benefits for managing weight. Meanwhile, GW0742 contributes to potential muscle regeneration, insulin sensitivity improvement, and neuroprotective effects. Together, these compounds represent a promising avenue for research into optimizing physical performance and metabolic health. As with any research compound, cautious use and consultation with healthcare professionals are recommended to mitigate potential risks and maximize benefits.

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Form	Capsules
Variant	60mg/60ct/3.6g

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